Streptomyces sp. ID38640: G7Z12_24780
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Entry
G7Z12_24780 CDS
T11207
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
stid Streptomyces sp. ID38640
Pathway
stid00790
Folate biosynthesis
stid01100
Metabolic pathways
stid01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stid00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
G7Z12_24780
Enzymes [BR:
stid01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
G7Z12_24780
6.3.2.17 tetrahydrofolate synthase
G7Z12_24780
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QIK08758
UniProt:
A0A6G7T034
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Position
5777017..5778531
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AA seq
504 aa
AA seq
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MSERPQNDDPDPTDAFDEMVEAETDRDPDLAVIEAGSRTLRAQAGPPQGDGIPARPADPE
VDRALRAVEEELAGRWGETKLDPSVQRIAALLDILGSPQRAYPSIHITGTNGKTSTARMI
EALLAAFDLRTGRYTSPHVQSITERISLDAAPISAERFIETYRDIAPYVEMIDGQQEYRL
SFFEVLTAMAYAAFADSPVDVAVVEVGMGGTWDATNVIDGDVAVITPISLDHTDRLGETP
EQIAGEKSGIIKKDATVVLAQQPVDAASVMLKRAVEVDATVAREGMEFGVLSREVAVGGQ
MLTLRGLGGEYPEIFLPLYGAHQAHNAAVALAAVEAFFGVGSEHARTLDIDTLRSAFAAV
TSPGRMEVVRRSPTVVLDAAHNPAGARAAAEAVTEAFGFSRLVGVVGASGDKDVRGFLEA
FEPIFAEIVVTRNSSHRAMDPDELAAIAVEVFGAERVQVEPRLDDALEAAITLAEEEGEF
SGAGVLVTGSVITVGEARLLMGRS
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgagcgcccccagaacgacgaccccgacccgaccgacgccttcgacgaaatggtc
gaggcggagaccgaccgtgacccggatcttgcggtgatcgaggccggcagccgcaccttg
cgcgcccaggccggcccgccgcagggggacgggatccccgcccggccggccgatcccgag
gtcgaccgtgcgctgcgcgccgtcgaggaggagctggcgggccgctggggtgagaccaag
ctcgacccgtcggtgcagcgcatcgcggcgctgctggacattctcggctcgccgcagcgg
gcctacccgtccatccacatcaccggcaccaacggcaagaccagcaccgcccgcatgatc
gaggccctgctggccgccttcgacctgcgcaccggccgctacacgagcccgcatgtccag
tccatcaccgagcggatcagcctggacgccgcgccgatctccgccgagcgcttcatcgag
acataccgcgacatcgccccgtatgtggagatgatcgacggccagcaggagtaccgcctg
tcgttcttcgaggtgctgacggcgatggcgtacgccgccttcgcggacagccccgtggac
gtcgcggtcgtcgaggtcggcatgggcggcacctgggacgcgacgaacgtcatcgacggc
gatgtcgccgtgatcaccccgatctcgctggaccacaccgaccggctgggggagacgccc
gagcagatcgccggtgagaagtccgggatcatcaagaaggacgccacggtcgtgctggcc
cagcagccggtggacgcggcgtcggtgatgctcaagcgcgcggtcgaggtggacgccacg
gtcgcccgtgagggcatggagttcggggtgctctcccgtgaggtggccgtcggcgggcag
atgctgacgctgcgcgggctgggcggcgagtacccggagatcttccttccgctgtacggc
gcccatcaggcgcacaacgccgcggtggccctcgccgcggtcgaggcgttcttcggcgtc
ggctcggagcacgcccgcacgctggacatcgacaccctccgctccgcgttcgccgcggtc
acctcgcccggccggatggaggtcgtgcgccgcagcccgacggtcgtgctggacgcggcc
cacaacccggcgggtgcgcgggcggcggccgaggccgtcaccgaggcattcgggttcagc
cggctggtcggcgtggtcggcgccagcggggacaaggacgtacggggcttcctggaggcc
ttcgagccgatcttcgccgagatcgtggtgacgcgtaattccagccatcgtgcgatggat
ccggatgagctggcggccatcgccgtcgaggtcttcggcgccgagcgagtccaggtggag
ccgcggctcgacgacgccctggaggcggcgatcaccctcgccgaggaagagggcgagttc
tccggcgccggtgtgctggtgaccggctcggtgatcacggtcggcgaggcccggctgctc
atggggaggagctga
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