KEGG   Streptomyces sp. ICC1: DRB96_02360
Entry
DRB96_02360       CDS       T10586                                 
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
stii  Streptomyces sp. ICC1
Pathway
stii00230  Purine metabolism
stii00670  One carbon pool by folate
stii01100  Metabolic pathways
stii01110  Biosynthesis of secondary metabolites
Module
stii_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:stii00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    DRB96_02360 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    DRB96_02360 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:stii04147]
    DRB96_02360 (purH)
Enzymes [BR:stii01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     DRB96_02360 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     DRB96_02360 (purH)
Exosome [BR:stii04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   DRB96_02360 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: AWZ17684
UniProt: A0A2Z4V8V1
LinkDB
Position
complement(493259..494848)
AA seq 529 aa
MTVESDDLTASKRPIRRALISVYDKTGLEELARGLHEAGVALVSTGSTASKIAAAGVPVT
KVEELTGFPECLDGRVKTLHPRVHAGILADLRLEDHRNQLAELGVEPFDLVVVNLYPFLE
TVQSGATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPARYGAVLAAAGAGGFDLTARK
RLAAEAFQHTAAYDVAVASWFTNAYAPEAPEDTAVLPEFLAGAWERKSTLRYGENPHQAA
ALYTDGQPGGLANAEQLHGKEMSYNNYVDTDAARRAAYDHEEPCVAIIKHANPCGIAVGK
DVAEAHRKAHACDTASAFGGVIAVNRPVSVELAEQVAEIFTEVIVAPGFEPGAVEVLAKK
KNIRVLKVEGHPHQPGDLKPISGGVLLQQSDAFQAEGDDPANWTLATGEALSADELADLA
FAWKACRAVKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGAERAQGSYAASDAFFP
FADGLEILTAAGIKAVVQPGGSMRDELVIEAAKAAGVTMYLTGTRHFFH
NT seq 1590 nt   +upstreamnt  +downstreamnt
gtgaccgtagagagcgacgacctcaccgcgtcgaagcgcccgatccggcgcgcgctcatc
agcgtctacgacaagacgggactggaagagctggcccgcggtctgcacgaggcgggtgtc
gcgctcgtctcgaccggctccaccgcctcgaagatcgccgccgccggggtgcccgtcacc
aaggtcgaggagctgaccggcttccccgagtgcctggacggccgggtcaagaccctgcac
ccgcgcgtgcacgccggcatcctcgccgacctgcgcctggaggaccaccgcaaccagctc
gccgagctgggcgtcgagcccttcgacctcgtggtcgtcaacctctaccccttcctcgag
accgtccagtcgggcgcgaccccggacgagtgcgtggagcagatcgacatcggcggcccc
tcgatggtccgcgccgccgccaagaaccacccctcggtggcggtcgtcaccagcccggcg
cgctacggcgccgtcctcgcggccgccggcgccggcggtttcgacctgaccgcccgcaag
cgactcgccgccgaggccttccagcacaccgccgcgtacgacgtcgccgtggcctcctgg
ttcacgaacgcgtacgccccggaagcccccgaggacacggccgtgctgcccgagttcctg
gccggcgcctgggagcgcaagtcgaccctgcgctacggcgagaacccgcaccaggccgcc
gcgctgtacacggacggacagccgggcgggctcgccaacgccgagcagctgcacggcaag
gagatgtcctacaacaactacgtggacaccgacgcggcccgccgcgccgcctacgaccac
gaagagccctgcgtcgcgatcatcaagcacgccaacccgtgcggcatcgcggtcggcaag
gacgtcgccgaggcccaccgcaaggcgcacgcctgcgacacggcctccgccttcggcggc
gtcatcgccgtcaaccgcccggtgagcgtcgagctcgccgagcaggtcgccgagatcttc
accgaggtcatcgtcgcccccggcttcgagccgggcgccgtcgaggtcctggccaagaag
aagaacatccgcgtcctgaaggtggagggccacccgcaccagccgggcgacctcaagccc
atctccggcggcgtgctgctccagcagtccgatgccttccaggccgagggcgacgacccg
gcgaactggaccctggccaccggcgaggccctgtccgccgacgagctcgccgacctagcc
ttcgcgtggaaggcctgccgcgccgtcaagtccaacgcgatcctgctcgccaaggacggc
gcctcggtcggcgtcggcatgggccaggtcaaccgcgtcgactccgcgaagctggccgtc
gagcgggcgggcgccgagcgcgcgcagggctcgtacgccgcgtccgacgccttcttcccc
ttcgcggacgggctggagatcctgacggccgccggcatcaaggccgtggtccagccgggc
ggttcgatgcgcgacgagctggtcatcgaggccgcgaaggcggcgggcgtgacgatgtac
ctcaccgggacccggcacttcttccactga

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