Streptomyces sp. ICC1: DRB96_23330
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Entry
DRB96_23330 CDS
T10586
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
stii Streptomyces sp. ICC1
Pathway
stii00290
Valine, leucine and isoleucine biosynthesis
stii00660
C5-Branched dibasic acid metabolism
stii01100
Metabolic pathways
stii01110
Biosynthesis of secondary metabolites
stii01210
2-Oxocarboxylic acid metabolism
stii01230
Biosynthesis of amino acids
Module
stii_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
stii01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DRB96_23330 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DRB96_23330 (leuC)
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NCBI-ProteinID:
AWZ14703
UniProt:
A0A2Z4V0L4
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Position
4924814..4926247
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AA seq
477 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFEGLRQAGRKVRRLDLTIAT
EDHNTPTIDIDKPIADPVSRTQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVTGALAEGVTA
KDLILAIIAKIGTGGGQGYILEYRGEAVEQLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLEGRDHAPVGEDWDAAVAYWKTLRTDEDAVFDAEVVVDGTTLAPFVTWGTNPGQGSPL
SANVPDPASYEDASERHAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAVAG
IIEGRKVANGVRMLVVPGSVRVALQAVAEGLDKVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLAGSSAATAPAGV
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgcggagggc
gagcccgatctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgaagggctgcgccaggccggccgcaaggtccgccgtctcgacctcaccatcgcgacc
gaggaccacaacacccccacgatcgacatcgacaagccgatcgccgatccggtctcccgg
acccagctggagacgctgcgcaagaactgcgccgagttcggcgtgcgcctgcactcgctg
ggcgacgtcgagcagggtgtcgtccacgtcgtggggccgcagctgggcctgacccagccg
ggcaccaccgtggtctgcggtgactcgcacacctccacgcacggcgccttcggcgcgctg
gccttcggcatcggcaccagccaggtcgagcacgtgctggcgacccagacgctgccgctg
gcccgccccaagacgatggcgatcaccgtcaccggcgcgctggccgagggcgtcaccgcc
aaggacctgatcctggccatcatcgccaagatcggcaccggcggcggccagggctacatc
ctggagtaccgcggcgaggccgtcgagcagctgtcgatggaagcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgaccagaccaccttc
gactacctcgagggccgcgaccacgccccggtgggcgaggactgggacgcggcggtcgcg
tactggaagaccctgcgcaccgacgaggacgcggtcttcgacgccgaggtcgtcgtcgac
ggcaccacgctggccccgttcgtcacctggggcaccaacccgggccagggctcgccgctg
tcggccaacgtccccgaccctgcttcgtacgaagacgcttcggagcgccacgccgccgaa
aaggccctggagtacatggggttgacggccggacagccgctgcgcgacatcaaggtcgac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgtcgccggc
atcatcgagggccgcaaagtcgccaacggcgtacggatgctggtcgtcccgggctccgtc
cgggtcgccctgcaggccgtggcggagggcctggacaaggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgttcgatgtgcctgggcatgaaccccgaccaactggcgccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggg
cgcacccacctggtctccccgcaggtggcagccgccaccgccgtactgggccacctggcc
tcgcccgccgacctggccggctcgtcggccgcgaccgcccccgcaggagtctga
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