Streptomyces sp. ICC1: DRB96_23840
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Entry
DRB96_23840 CDS
T10586
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stii Streptomyces sp. ICC1
Pathway
stii00300
Lysine biosynthesis
stii00550
Peptidoglycan biosynthesis
stii01100
Metabolic pathways
stii01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stii00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DRB96_23840
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DRB96_23840
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DRB96_23840
Enzymes [BR:
stii01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DRB96_23840
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
AWZ14789
UniProt:
A0A2Z4V203
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All DBs
Position
complement(5033889..5035313)
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AA seq
474 aa
AA seq
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MIALSLAEIADITGGRPHDIPDPSVRITGPVVIDSRQVEPGSLFAAFAGEQVDGHDYAER
AVAAGAAAVLAARPVGVPAIVVPDVEKALGALARAVVERLGTDVVALTGSAGKTSTKDLI
AQVLQTHAPTVWTPGSLNNEIGLPLTALKAAEDTRHLVLEMGARGIGHIDYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPAAADGGIAVLNADDPLVRPMSARTKART
VLFGEAEDADVRATEVRMTPAGQPSFTLHTPTGCGEVTLRLYGEHHVSNALAAAAVAHVL
GMSVEEIATALSGAGTLSRWRMEVTERADGVTIVNDAYNANPESMRAALRALAAMGGSAR
ANGGRTWAVLGPMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVLVSDAQAAVDLLRSELRPGDVVLVKASRSIGLERVALALLEREGEVAGR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctttccctcgccgagatcgccgacatcaccggcgggcggccccacgacata
ccggatccgtccgtccgcatcaccgggccggtcgtcatcgactcccgccaggtggagccc
ggcagcctgttcgccgcgttcgccggcgagcaggtcgacggccacgactacgccgagcgc
gcggtcgccgccggcgccgcggccgtgctcgcggcccgccccgtcggcgtcccggcgatc
gtcgtccccgacgtcgagaaggcgctcggcgccctcgcccgggccgtcgtcgaacgcctg
ggcaccgacgtggtggccctgaccggctccgccgggaagacgtccaccaaggacctcatc
gcccaggtgctccagacccacgcgcccacggtgtggacgcccggctccctcaacaacgag
atcggcctgccgctcaccgcgctcaaggccgccgaggacacccggcacctggtgctggag
atgggtgcccgcgggatcggccacatcgactacctcaccggcctgacgcccccgcgcatc
ggcctcgtcctgaacgtcggcaccgcccacatcggcgagttcggcggccgggaacagatc
gcccaggccaagggcgagctggtggaagccctgccggcggcggccgacggcgggatcgcc
gtgctgaacgccgacgaccccctggtccgcccgatgtccgcgcgcaccaaggcccgcacg
gtcctgttcggggaggccgaggacgccgacgtacgggccaccgaggtgcggatgacaccg
gcgggacagccctccttcacactccacacacccaccgggtgcggcgaagtgaccttgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgtactg
ggcatgtccgtcgaagagatcgccaccgcgctctccggggcgggcaccctgtcccggtgg
cggatggaggtcaccgagcgggcggacggcgtgacgatcgtcaacgacgcctacaacgcg
aatcccgagtccatgcgggccgccctgcgcgcgcttgccgcgatgggcggcagcgccagg
gccaacgggggacgtacgtgggcggtgctcggccccatggccgagttgggtgacgcgtcg
ctggccgagcacgacgcggtgggacggcttgccgtccggctcaacgtgagcaagctcgta
gcagtcgggggcagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgctcgtgtccgacgcgcaggcggcggtcgacctgttgcgcagtgaa
ctgcgcccgggagacgtcgtgctggtgaaggcttccaggtccattggtctggagcgggtc
gcgctggcgttgctggagcgcgagggcgaggtcgccggccgatga
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