Streptomyces sp. ICC1: DRB96_36235
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Entry
DRB96_36235 CDS
T10586
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
stii Streptomyces sp. ICC1
Pathway
stii00270
Cysteine and methionine metabolism
stii00480
Glutathione metabolism
stii01100
Metabolic pathways
stii01240
Biosynthesis of cofactors
Brite
Enzymes [BR:
stii01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
DRB96_36235 (egtA)
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NCBI-ProteinID:
AWZ16745
UniProt:
A0A2Z4V8C6
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Position
7751011..7752303
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AA seq
430 aa
AA seq
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MPQVPPRLTESGAEDLIHGICFKTGPPRLLGAELEWLVFDAEHPALPVSHERLADAHGAA
RALPLGSRVTVEPGGQLELSSAPATSLTGCVDGLQADLAAVRRALRDRGLVLRGLGQDPR
RPQRRMLASPRYDAMETYFDRTGPAGRAMMRSSASVQVCVDSGHEEPGPLGHGRRWRLAH
LLGAVLVAAFANSPAHEGPYAGWRCARQGIWSDIDTRRSLAPALDAEPRGAWTRQALDTE
VMCVRTPGEGVPWAVPRGLTFRDWVRSGGGPRPPTAEDLDYHLTTLFPPVRPRGHLELRM
IDAQPGDDGWVIPVAVVHALFDDPEAAETAYRVAKGLADTYGAQPAPRNPLWRTAARDGL
SDPELRAAARACFRAATEALPRLGAGTVVRDAVAEFTDRHVARGRCPADERSGQHAHDPW
SLPAGEEARS
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
atgccccaggtaccaccccgcctgaccgagtccggcgccgaggacctgatccacggcatc
tgtttcaagaccggcccgccccgcctgctaggggcggagctcgaatggctggtgttcgac
gccgagcaccccgccctgcccgtgtcccacgagcggctggccgacgcgcacggggcggcc
cgcgcgctgcccctgggatcccgcgtcaccgtcgagcccgggggccagctggagctgagc
tcggcgcccgccacctcgctcaccgggtgcgtggacggcctccaggccgacctggccgcc
gtacgccgcgccctgcgcgaccggggcctcgtgctgcgcggcctgggccaggacccgcgc
cggccgcagcgccggatgctggccagcccgcgctacgacgcgatggagacctacttcgac
cgcaccggtcccgccggccgcgccatgatgcgctcctccgcttccgtgcaggtgtgcgtg
gactccgggcacgaggagccgggcccgctcggccacggccgccggtggcgcctggcccac
ctgctcggcgccgtactggtcgccgccttcgccaactcgcccgcgcacgaagggccgtac
gccggctggcggtgtgcccgccagggcatctggagcgacatcgacacccgccgctccctc
gccccggcgctggacgcggagccgcgcggcgcgtggacccggcaggcgctggacaccgag
gtgatgtgcgtacggacgcccggggagggcgtgccctgggcggtgccgcgcgggttgacc
ttccgcgactgggtgcgctccgggggcggcccgcggccgcccaccgcggaggatctggac
taccacctgaccacgctcttcccgccggtccggcctcgcgggcatctggagctgcggatg
atcgacgcccagcccggcgacgacggctgggtcatcccggtggccgtggtccacgcgctg
ttcgacgacccggaggccgcggagaccgcgtaccgggtggcgaagggactggccgacacc
tacggggcgcagcccgcgccccgcaatccgctgtggcgaaccgccgcgcgggacggcctg
tccgatcccgagcttcgggccgccgcccgggcctgcttccgggccgcgaccgaggcgctg
ccccggctgggcgccggaaccgtcgtccgggacgcggtggcggagttcaccgaccgccac
gtggcgcgcgggcgatgtcccgccgacgaacggagcggtcagcacgcgcacgatccgtgg
tcgctgccggccggtgaggaggcgcgctcatga
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