Streptomyces tirandamycinicus: DDW44_03700
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Entry
DDW44_03700 CDS
T06843
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stir
Streptomyces tirandamycinicus
Pathway
stir00300
Lysine biosynthesis
stir00550
Peptidoglycan biosynthesis
stir01100
Metabolic pathways
stir01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stir00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DDW44_03700
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DDW44_03700
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DDW44_03700
Enzymes [BR:
stir01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DDW44_03700
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AWI27993
UniProt:
A0A2S1SNL6
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All DBs
Position
complement(848331..849767)
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AA seq
478 aa
AA seq
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MISLSLAEIAEAVGGQLHDIPDPSVRVTGPVVRDSREVVPGSLFVAFAGARVDGHDYAAD
VVAAGAAAVLASRPVGVPAVVVDDVQRALGALARAVVRRLGATLVALTGSAGKTSTKDLI
AQVLRRKAPTVWTPGSLNNEIGLPLTALSATDETRFLVLEMGARGIGHIRYLTQLTPPRV
GVVLNVGSAHIGEFGGREQIAEAKGELVETLPSAEAGGVAVLNADDPLVRAMSARTRARV
VLFGESDEADVRAENVRLLPGGQPAFLLRTPSGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMSVDEIATALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGTAAE
AAGGRTWAVLGPMAELGGEALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRRELRPGDVVLVKASRSAGLERIAEALLADTPPAEGQVAGR
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
gtgatcagcctctccctcgccgagatcgccgaagccgtcggcgggcagctccacgacata
ccggatccgtccgtacgcgtcaccgggcccgtcgtccgcgactcccgcgaggtcgtgccc
ggcagcctcttcgtcgccttcgccggcgcccgcgtcgacggccacgactacgccgcggac
gtggtcgccgcgggtgcggccgccgtactggcctcgcggcccgtcggtgttcccgccgtc
gtcgtggacgacgtccagagggccctcggcgcgctggcccgcgccgtggtgcggcgcctc
ggcgccaccctggtggccctcaccggctccgcggggaagacgagcaccaaggacctcatc
gcccaggtgctgcgccgcaaggcgccgaccgtgtggacccccggctcgctcaacaacgag
atcggtctgccgctgaccgcgctcagcgccaccgacgagacccggttcctggtcctcgag
atgggcgcccgcggcatcggccacatccgctacctcacccagctcaccccgccccgcgtc
ggcgtggtgctgaacgtcggcagcgcccacatcggcgagttcggcggccgcgagcagatc
gccgaggccaagggcgagctcgtggagacgctgccctccgccgaagcgggcggggtggcc
gtcctcaacgccgacgatcccctcgtccgcgccatgtcggcccgtacccgggcacgtgtc
gtgctgttcggtgagtcggacgaagcggacgtacgcgccgagaacgtccgactcctgccc
ggtggacagcccgcattcctgcttcgcacaccctccgggtgcagcgacgtgaccttgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgtcgacgagatcgccaccgcgctctcggaggccggcaccctctcccgctgg
cgtatggaggtcaccgagcgtccggacggcgtcacgatcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgcgccgcactccgtgcgctcgccgccatgggcacggccgccgag
gccgccggggggcgcacgtgggcggtgctcggtccgatggccgagctcggcggtgaggcg
ctggccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcgggggcagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcaggcggcggtcgacctgttgcgcagagag
ctgcgcccgggagacgtcgtgctggtgaaggcttccaggtcggccgggctcgagcggatc
gccgaggcgctgctcgccgacacccctccggccgaggggcaggtcgccggccgatga
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