Streptomyces tirandamycinicus: DDW44_22000
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Entry
DDW44_22000 CDS
T06843
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
stir
Streptomyces tirandamycinicus
Pathway
stir00290
Valine, leucine and isoleucine biosynthesis
stir00660
C5-Branched dibasic acid metabolism
stir01100
Metabolic pathways
stir01110
Biosynthesis of secondary metabolites
stir01210
2-Oxocarboxylic acid metabolism
stir01230
Biosynthesis of amino acids
Module
stir_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
DDW44_22000 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DDW44_22000 (leuC)
Enzymes [BR:
stir01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
DDW44_22000 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
DDW44_22000 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AWI31155
UniProt:
A0A2S1SXN8
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All DBs
Position
4965609..4967042
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AA seq
477 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLYIDLHLLHEVTSPQAFDGLRQSGRRVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMARPRTMAITVEGELPDGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLRGRDHAPEGEDWDAAVAYWKTLRTDDDAVFDAEVFIDAAELSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLTAGQPLRDIRVDTVFVGSCTNGRIEDLRAAAD
ILTGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLTDASATPAPAGV
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgggcaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagccagacctcctctacatcgatctccacctcctgcacgaggtgacgagcccgcaggcg
ttcgacggtcttcgtcagagcggccgccgggtgcggcggctcgacctcaccatcgcgacc
gaggaccacaacaccccgaccctggacatcgacaagcccatcgccgacccggtctcccga
gcccagctggagaccctgcgcaagaactgcgcggagttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtggtgcacgtggtgggaccgcagctgggactgacccagccg
ggcaccacggtggtctgcggcgactcccacacctccacccacggcgccttcggcgcgctg
gcgttcggcatcggaacctcgcaggtcgagcacgtcctggccacccagacgctgcccatg
gcccgccccaggaccatggcgatcaccgtggagggggagctgcccgacggagtcaccgcc
aaggacctgatcctggccatcatcgccaggatcggcaccggcggcggccagggctacgtc
ctggagtaccggggctccgccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggtgcccgggcgggcatgatcgcccccgaccagaccacgttc
gactacctgcggggacgcgaccacgcgcccgagggcgaggactgggacgccgcggtcgcg
tactggaagaccctgcgcaccgacgacgacgcggtcttcgacgccgaggtgttcatcgac
gccgccgagctctcccccttcgtcacctggggcaccaaccccggccagggcgccccgctc
tccgccagcgtccccgacccggcatcgtacgaggacgcatcggagcgcctcgcggccgaa
aaggccctggagtacatggggttgaccgccggccagccgctgcgcgacatccgggtcgac
accgtcttcgtaggctcctgcaccaacggccgtatcgaggacctgcgcgccgccgcggac
atcctcaccggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctcggtg
cgcgtcgcgctgcaggccgtcgaggagggcctggacaaggtcttcaaggaagccggcgcc
gaatggcggcacgcgggttgctcgatgtgcctgggcatgaaccccgaccagctcgccccc
ggggagcgctcggcctccacctccaaccgcaacttcgaggggcgccagggcaagggcggc
cgcacccacctggtctcaccgcaggtcgccgccgccaccgcggtcctcggccacctcgcc
tcacccgccgacctgaccgacgcgtccgccacgcccgcacccgccggagtctga
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