KEGG   Streptomyces tirandamycinicus: DDW44_22040
Entry
DDW44_22040       CDS       T06843                                 
Name
(GenBank) D-alanine--D-alanine ligase A
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
stir  Streptomyces tirandamycinicus
Pathway
stir00470  D-Amino acid metabolism
stir00550  Peptidoglycan biosynthesis
stir01100  Metabolic pathways
stir01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:stir00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    DDW44_22040
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    DDW44_22040
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    DDW44_22040
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:stir01011]
    DDW44_22040
Enzymes [BR:stir01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     DDW44_22040
Peptidoglycan biosynthesis and degradation proteins [BR:stir01011]
 Precursor biosynthesis
  Amino acid ligase
   DDW44_22040
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp ATP-grasp_4
Other DBs
NCBI-ProteinID: AWI31163
UniProt: A0A2S1SXK4
LinkDB
Position
4971922..4973094
AA seq 390 aa
MSENQSQSTGLAPTGGEALRKPRVAVVFGGRSSEHAISVVTAGAVLRAIDRTKYEVLPIG
ITADGRWALTADEPDRMAIADRRLPSVGDLAESAEGGVVLSVDPANREVVYSEPGSVPKA
LGEVDVVFPVLHGPYGEDGTLQGLLELAGVPYVGSGVLASAVGQDKEYMKRVFASFGLPV
GPYTVLRPREWEQDPSAARRKIVDFAGEHGWPLFVKPARAGSSIGITKVDDLAGLDEAVE
EARRHDPKVIVEALLRGREIECGVLEFEDGPRASVPAEIPPVSAHDFYDFEAKYIDSATG
LVPAPLTGEQTAEVQRLAVEAFEAASCEGLVRADFFLTESGEFVINEINTMPGFTPISMY
PRMWQESGVDYAELVDRLVQAALRRSTGLR
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgagcgagaaccagtcccagagcaccggccttgcccccaccggcggtgaggcgctccgc
aagccgcgcgtcgcggtcgtcttcggcggccgaagctccgagcacgcgatctccgtcgtg
acggccggcgcggtactgcgtgccatcgaccgcaccaagtacgaggtccttcccatcggc
atcacggcggacggccgctgggcgctcaccgccgacgagcccgaccggatggccatcgcc
gaccggcggctgccgtccgtcggcgacctcgccgagtcggccgagggcggcgtggtcctc
tccgtcgaccccgccaaccgcgaggtcgtctacagcgagccgggctccgtccccaaggcc
ctcggcgaggtcgacgtcgtcttccccgtgctgcacggtccgtacggcgaggacggcacg
ctccagggcctgctcgagctcgccggagtcccctacgtgggatccggcgtgctcgcctcg
gccgtcggccaggacaaggagtacatgaagcgcgtcttcgcctccttcggactgccggtc
ggcccctacacggtgctccggccccgggagtgggagcaggatccttccgccgcccgcagg
aagatcgtcgacttcgccggtgagcacggctggccgctgttcgtgaagcccgcccgcgcc
ggttcctcgatcggcatcaccaaggtcgacgacctcgccgggctggacgaggccgtggag
gaggcccggcgccacgaccccaaggtcatcgtggaggcgctgctgcgcggccgcgagatc
gagtgcggtgtgctggagttcgaggacggcccccgtgccagcgtgccggccgagatcccg
cccgtttccgcgcacgacttctacgacttcgaggccaagtacatcgactcggccaccggg
ctggtgcccgcgccgctcaccggcgagcagaccgccgaggtgcagcggctcgccgtcgag
gcgttcgaggccgcgtcctgcgaggggctggtccgcgcggacttcttcctcaccgagtcg
ggcgagttcgtgatcaacgagatcaacaccatgccgggcttcacgcccatctccatgtac
ccgcgcatgtggcaggagtccggggtcgactacgcggaactcgtcgaccgtctggtccag
gcggcgctccgccgctccaccggcctgcgctga

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