Streptomyces sp. JL2001: ACE1OA_25585
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Entry
ACE1OA_25585 CDS
T11502
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stjl Streptomyces sp. JL2001
Pathway
stjl00300
Lysine biosynthesis
stjl00550
Peptidoglycan biosynthesis
stjl01100
Metabolic pathways
stjl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stjl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ACE1OA_25585 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ACE1OA_25585 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ACE1OA_25585 (murF)
Enzymes [BR:
stjl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ACE1OA_25585 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
XVL72122
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Position
5739868..5741292
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AA seq
474 aa
AA seq
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MIALSLAEIAEIVGGQSYDIPDPAALVTGPVVIDSREVKTGSLFAAFAGEHVDGHDYAVR
AVEAGATAVLAARPVGVPAIVVADVQSALGALARAVVERLGTDVVALTGSAGKTSTKDLI
AQVLQHHAPTVWTPGSLNNEIGLPLTALRAGDDTRHLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVESLPPADRGGVAVLNADDPLVRAMASRTRARV
TLFGESDEAAVRAENVRLTASGQPSFKLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMPVEEIATALSEAGTLSRWRMEVTERSDGVTIVNDAYNANPESMRAALRALAAMGRATR
AQGGRTWAVLGRMAELGDASLVEHDAVGRLAVRLNVSKLVAVGDREASWLQLGAYNEGSW
GEESVHVSDARAAIDLLRSELRPGDVVLVKASRSVGLEQVALALLDSESEVSGR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgaaatcgtcggcgggcagtcgtacgacata
ccggatccggccgcactggtcaccggtcccgtcgtcatcgactcccgcgaggtgaagacc
ggcagcctcttcgccgccttcgccggtgagcacgtcgacggccacgactacgcggtgcgc
gccgtcgaggcgggcgcgacggccgtcctggccgcgcgccccgtcggcgtgcccgccatc
gtcgtggccgacgtccagagcgccctcggagccctcgcccgcgcggtcgtcgaacgcctc
ggcaccgacgtcgtcgcgctcaccggctccgccggcaagacctccacgaaggacctgatc
gcccaggtcctccagcaccacgcccccaccgtgtggacccccggctcgctcaacaacgag
atcgggctgccgttgaccgcgctgcgcgcgggcgacgacacccggcacctcgtcctcgag
atgggcgcccggggcatcggccacatccgctacctcaccggactgaccccgccgcgcatc
ggactcgtcctgaacgtggggaccgcccacatcggcgagttcgggggccgcgagcagatc
gcgcaggccaagggcgagctcgtcgagtccctgccgcccgccgaccggggcggcgtggcg
gtcctcaacgccgacgaccccctcgtccgcgccatggcgtcgcgcacccgcgcgcgcgtg
acgctgttcggagagtcggacgaagcggccgtacgtgccgagaacgtccggctcacagcg
agcggacagccctctttcaagctccacacacccaccgggtgcagtgacgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcgcacgagctg
ggcatgcccgtcgaggagatcgccaccgcgctctccgaggcagggaccctgtcgcgctgg
cgcatggaggtcaccgagcgttcggacggcgtgacgatcgtcaacgacgcctacaacgcc
aaccccgagtccatgcgggccgccctgcgcgcgctcgcggccatggggcgggcgactcgg
gcccaggggggccggacgtgggcggtgctcggcaggatggccgagctcggtgacgcgtcg
ctcgtcgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtg
gcggtcggggacagggaagcgtcctggttgcaactgggcgcttataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcgatcgacctgttgcgcagtgag
ctgcgcccgggagacgtcgtgctggtgaaggcgtccaggtcggtaggcctcgaacaggtc
gccctggcactgctcgactccgagagcgaggtttccggccgatga
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