Salmonella enterica subsp. enterica serovar Typhimurium LT2: STM0124
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Entry
STM0124 CDS
T00065
Symbol
murF
Name
(RefSeq) D-alanine:D-alanine-adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stm
Salmonella enterica subsp. enterica serovar Typhimurium LT2
Pathway
stm00300
Lysine biosynthesis
stm00550
Peptidoglycan biosynthesis
stm01100
Metabolic pathways
stm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
STM0124 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
STM0124 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
STM0124 (murF)
Enzymes [BR:
stm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
STM0124 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-GeneID:
1251642
NCBI-ProteinID:
NP_459129
UniProt:
Q8ZRU6
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All DBs
Position
144963..146321
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AA seq
452 aa
AA seq
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MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKAN
GAGALLVSRPLDIDLPQVIVKDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRLVWRFS
PNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATL
TAIKAGLAALKAVPGRLFPIQLSENQLVLDDAYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEACHLQVGEAAKAAGIDRVLSTGKLSQAISHASGVGEHFADKAALIARLHAL
LQEQPMMTILVKGSRSAAMEDVVHALQEKGSC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgctcagcaaaattgccgatgtccttggcgccgaacaccgcggggcg
gatctcacgctcgatacggtcattaccgacacacggaaagtgacgccgggatgcctgttc
gtggcgctgaaaggggaacgctttgatgcgcatgattttgctgataaagcaaaagcgaac
ggcgctggcgccctgctggtcagtcgtcctctggatatcgatctcccgcaggtgattgta
aaagacacgcgtcaggcatttggccaactggccgcctgggtacgtatgcaggtaccggcg
cgggtggtggcgttaaccggttcgtccggcaaaacctcggtcaaagagatgaccgccgcg
attcttagccagtgcggaaatactctgtataccgcaggcaattttaacaacgacatcggc
gtgccgataacgctgctgcgcttaaaccatgattatgactatgcggtaatcgagttaggc
gctaatcaccagggagaaatcgcctggaccgttagcctgacgcgcccggaagcggcgctg
gtcaataacctggcggcggcgcatctggaaggcttcggctcgttggccggcgtggcgaaa
gcgaaaggcgaaatctataccggtttgcctgagaacggtatcgcgattatgaatgccgat
aataatgactggctgaactggcaaagcattattggcgatcgtctggtgtggcgcttttcg
ccgaatgcggcaaacagcgactttaccgctgcgaatatccacgtgacgtcacacggtacc
gaatttaccctgcaaacgccgatgggcagcattgatgtgctgctgccgttgccggggcgg
cacaatattgccaacgcgctggcggccgctgctttatcaatggcggtgggggctacgctg
acggcgattaaagcagggctggcggcgttaaaagccgtacccgggcgtctgttcccgatt
cagctaagtgaaaaccaactggtactggatgacgcttataacgccaacgttggttcgatg
accgccgcagtgcaggtcctttctgaaatgcccggctaccgcgtgctggtggtaggcgat
atggccgagctgggcgcagaaagcgaagcgtgccacctccaggttggtgaggccgcaaaa
gcggcgggtattgatcgcgtgttaagcaccggaaaactcagtcaggctatcagccacgcc
agcggcgtcggcgaacattttgccgataaagccgcgctcattgcgcgtttacacgctctg
cttcaggagcaaccaatgatgactattttagtgaaaggatcacgcagcgccgcgatggaa
gatgtggttcatgcgttacaggagaaaggttcatgttag
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