Salmonella enterica subsp. enterica serovar Typhimurium LT2: STM2565
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Entry
STM2565 CDS
T00065
Symbol
purG
Name
(RefSeq) phosphoribosylformylglycinamidine synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
stm
Salmonella enterica subsp. enterica serovar Typhimurium LT2
Pathway
stm00230
Purine metabolism
stm01100
Metabolic pathways
stm01110
Biosynthesis of secondary metabolites
Module
stm_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
stm00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
STM2565 (purG)
Enzymes [BR:
stm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
STM2565 (purG)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-GeneID:
1254087
NCBI-ProteinID:
NP_461500
UniProt:
P74881
Structure
PDB
PDBj
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Position
complement(2708255..2712142)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQ
YGPALSSHTPAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEASTLT
AEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGL
ALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKM
IKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTIGDRTV
TGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMS
MKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAEMAFA
GHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLGQALA
GDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPGLNVK
LSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRI
GLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPH
PERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtctgcattccgtatcaataaactgctg
gcgcgctttcaggctgccaacctccaggtccacaatatatacgctgagtatgtccatttt
gctgacctgaacgccccgttaaatgatagcgagcaggcgcagcttacccgtctgctgcaa
tacggcccggcgcttagcagccatacgccggcgggtaaactcctgttggtcacaccgcgt
cctggtaccatctccccctggtcttcaaaagcaacggatatcgcccacaactgcggcctg
caacaggttgatcgtctggagcgcggcgtagcgtactatatcgaggcttcgacgttgacg
gcggaacagtggcgacaagtggccgcagagctgcacgaccgtatgatggagacggtgttc
tcttctttaaccgatgcggaaaaactgtttatccaccatcagcctgcgccggtttccagt
gtcgatctgctgggagaaggccgtcaggcgttaattgacgccaacctgcgtcttggtctg
gcgctggcggaagatgaaatcgactatttgcaggaggcgtttaccaaactggggcgcaac
ccgaacgatatcgaactgtacatgttcgcccaggcgaactccgagcactgccgccacaag
atttttaacgccgactggattatcgacggtaaaccgcagccgaagtcgctgtttaaaatg
attaaaaacaccttcgaaaccacgccggactatgtgctctctgcctataaagacaatgcc
gcggtgatggaaggatctgcggtggggcgctacttcgccgaccacaataccggccgttac
gattttcatcaggagcccgcgcacattctgatgaaggtcgaaacgcataaccacccaacc
gccatctctccgtggccgggggcggcgaccggttccggcggcgaaattcgtgatgaaggc
gccaccgggcgtggcgcgaaaccaaaagccgggctggtgggcttctccgtttccaacctg
cgtattccgggctttgaacagccgtgggaagaggattttggcaagccggaacgtattgtc
accgcgctggatatcatgaccgaaggtccgctgggcggcgcggcgtttaacaacgaattt
ggtcgcccggcgctgaccggttacttccgtacttatgaagagaaagtgaacagccacaac
ggcgaagagctgcgcggctaccataagccgatcatgctggcgggcgggatcggtaatatt
cgcgccgatcacgtgcagaaaggcgagatcgtcgtgggcgcgaagctgatcgtccttggc
ggcccggcgatgaatatcggcctcggcggcggcgcggcatcgtcaatggcttccggccag
tctgatgcggatctcgattttgcctctgttcagcgcgacaacccggaaatggaacgccgc
tgccaggaagtgatcgaccgctgctggcagttgggcgacgctaacccaatcttgtttatc
catgatgtgggcgcgggcggtctctccaacgccatgccggagctggtgagcgacggcggg
cgcggcgggaaattcgaactgcgcgacattcttagcgacgagccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggagcgctatgtgctggcggtcgcggctgaccagttg
ccgctgttcgatgaactgtgtaagcgcgaacgcgcgccgtatgcggtcattggcgacgct
accgaagaacagcatctctcgttgcatgataaccatttcgacaatcagccgatcgacctg
ccgctggatgtcctgctgggcaaaacgccgaaaatgacccgcgatgtgcaaacattgaag
gcgaaaggcgatgcgctgaaccgcgcggatatcacgattgccgacgcggtaaagcgtgtt
ctgcatctgccgaccgtggcggaaaaaaccttccttgtcactattggcgaccgtaccgtc
accggtatggtggcgcgtgaccagatggttggcccgtggcaggtcccggtggctgactgc
gcggtcactaccgccagcctcgacagctactacggcgaagcgatgtcgattggcgagcgc
gcgccggtggcgctgctggactttgccgcctccgcccgtctggccgtcggtgaagcgttg
actaacattgccgcgacgcagattggcgatatcaagcgcattaagctttccgctaactgg
atggcggcagccggtcatcctggcgaagatgccggtttatatgacgcggttaaagcggtg
ggagaggaactctgtccgcagcttggcctgactattccggtgggcaaagattcgatgtcg
atgaaaacccgctggcaggaaggcaacgaacagcgcgaaatgacctcgccgctgtcgctg
gtgatttccgcgtttgcccgcgtggaagacgtgcgtcacacccttacgccgcagctttca
acggaagataacgccttgctgctgatcgatctcggcaagggccacaacgcgctgggcgca
acggcgttggcgcaggtctatcgtcagcttggcgacaaacccgcggacgtgcgtgacgtc
gcgcaactgaaaggcttctatgacgccatgcaggcgctggtcgctgcgcgtaaattactg
gcctggcacgaccgttccgacggcggtctgctggtgacgctggccgagatggcctttgcc
ggccactgcggcgtgcaggtcgatattgccgcgctgggcgatgaccatctggccgcactg
ttcaacgaggagctgggcggcgtgattcaggtacgcgctgaagacagagacgcggtcgaa
gcgctattggcgcagtacggccttgctgactgcgtccactaccttggtcaggccctggct
ggcgatcgctttgtgattaccgctaatgaccagacggtattcagcgaaagccgcactaca
ctgcgtgtctggtgggcggaaaccacctggcagatgcagcgtctgcgcgacaatccgcaa
tgtgccgaccaggaacacgaggcgaaagcgaatgataccgatccgggcctcaacgtgaag
ctgtcgtttgatattaatgaagatatcgccgcgccgtacattgcgacaggcgcacgaccg
aaagtcgctgtactgcgcgagcagggggtgaactctcacgtggagatggcggcggcgttc
catcgtgcgggctttgacgcgattgacgtccatatgagcgacctgctgggcggtcgtatc
ggtctgggtaacttccatgcgctggtggcttgcggcggcttttcctacggcgacgtgctg
ggggcgggcgaaggctgggcgaaatccattctgtttaaccatcgggtgcgcgacgaattc
gaaaccttcttccatcgtccgcagacgctggcgctgggcgtgtgcaacggttgccagatg
atgtcgaatctgcgcgagctgatcccgggcagcgaactgtggccgcgttttgtacgtaac
cattctgaccgcttcgaagcccgcttcagcctggtagaagtgacgcaaagcccatcgctg
ctgctgcaaggaatggtaggctcacagatgccgattgcggtttcccatggggaagggcgc
gttgaggtgcgtgacgatgcgcatcttgccgcgcttgagagcaaaggcctggtcgctctg
cgctacgttgataactttggtaaggtgaccgaaacctatccggctaacccgaacggttcg
ccgaacggcatcacggcggtgacgaccgaaaacggtcgggtgacgattatgatgccgcat
ccggaacgcgtattccgcaccgtcgccaactcctggcacccggaaaactggggcgaggat
agcccgtggatgcgtatcttccgtaatgcgcgtaagcagcttggttaa
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