Salmonella enterica subsp. enterica serovar Typhimurium LT2: STM2818
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Entry
STM2818 CDS
T00065
Symbol
gshA
Name
(RefSeq) gamma-glutamate-cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
stm
Salmonella enterica subsp. enterica serovar Typhimurium LT2
Pathway
stm00270
Cysteine and methionine metabolism
stm00480
Glutathione metabolism
stm01100
Metabolic pathways
stm01240
Biosynthesis of cofactors
Module
stm_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
stm00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
STM2818 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
STM2818 (gshA)
Enzymes [BR:
stm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
STM2818 (gshA)
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Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-GeneID:
1254341
NCBI-ProteinID:
NP_461744
UniProt:
O68838
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Position
complement(2966939..2968495)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGEAAKEKISAGY
FRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYARIGVEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLA
DAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTL
DSIHGGEEYQKVCDELVACFDNPELTFSARILRSMIDEGIGGTGKAFGEAYRNLLREEPL
EILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggctctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgcgggttagagcgcgaaacgctgcgtgtcaatgctgatggcacgctggcg
acaacaggtcatcctgaagcgttaggttcagcgctgacccataaatggattaccacagat
tttgcggaagccctactggagtttattacgccagtcgatggcgatatccagcatatgctc
acctttatgcgcgatctccatcggtatacggccaggaaactgggcgatgagcggatgtgg
ccattaagtatgccctgctatattgcggaagggcaggacatagagctggcgcagtacggc
acatccaataccgggcgttttaagacgctctatcgcgaagggctgaaaaatcgttatggc
gctttgatgcaaaccatctccggcgtacattacaatttttcattaccgatggcgttctgg
caggcgaaatgcggcgttacggaaggcgaagcggcaaaagaaaaaatttctgccggctat
tttcgtctgattcgcaactattaccgttttggctgggtcatcccctatctgtttggcgcg
tctccggccatttgttcctctttcctgcaaggaaagccaaccacattaccgtttgaaaaa
acggactgcggcatgtactacctgccgtatgcgacgtcgctgcgtttgagtgatttgggc
tataccaataagtcgcaaagcaatctcggaattacgtttaacgatttgcatgaatacgtt
gcaggtctgaagcgcgcgattaaaaccccttccgaggagtacgcacggattggtgtggaa
aaagacggtaagcggctacagattaacagcaacgttctgcaaattgaaaatgagctgtac
gcgcccattcgtcccaagcgcgtgacgcgcagcggcgaatcgccttctgacgcgcttctg
cgtggtggtattgagtatattgaagttcgttctctcgatattaatccgttctcaccgatc
ggcgtagacgagcaacaggtgcgcttcctcgatctgtttatggtctggtgcgtattggcc
gatgcgccggaaatgagtagcgatgagctgttatgtacgcgtactaactggaatcgcgtt
attctggaagggcgtaagccgggcctgacgttaggcattggctgtgaaactgcgcagttc
ccgctgcccaaagtcgggaaagatcttttccgcgatctgaaacgcgtggcgcaaacgctg
gacagtatccacgggggagaggagtatcaaaaggtgtgtgacgagttggtcgcctgcttt
gataatcctgaactgacattctccgcccggatcctacggtctatgattgatgaaggcatt
ggcggcaccgggaaagcgttcggtgaggcttaccgtaatctgttacgcgaagagccgctg
gagattttacaggaagaagagtttattgctgaacgtgacgcttcagtacgtcgtcagcag
gagattgaggcggcggataccgagccgtttgccgcgtggcttgcaaaacacgcctga
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