KEGG   Sphaerodactylus townsendi (Townsend's least gecko): 125438330
Entry
125438330         CDS       T08213                                 
Symbol
PIK3CA
Name
(RefSeq) LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
stow  Sphaerodactylus townsendi (Townsend's least gecko)
Pathway
stow00562  Inositol phosphate metabolism
stow01100  Metabolic pathways
stow04012  ErbB signaling pathway
stow04068  FoxO signaling pathway
stow04070  Phosphatidylinositol signaling system
stow04081  Hormone signaling
stow04140  Autophagy - animal
stow04150  mTOR signaling pathway
stow04210  Apoptosis
stow04218  Cellular senescence
stow04370  VEGF signaling pathway
stow04510  Focal adhesion
stow04620  Toll-like receptor signaling pathway
stow04625  C-type lectin receptor signaling pathway
stow04810  Regulation of actin cytoskeleton
stow04910  Insulin signaling pathway
stow04914  Progesterone-mediated oocyte maturation
stow05100  Bacterial invasion of epithelial cells
stow05132  Salmonella infection
stow05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:stow00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    125438330 (PIK3CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    125438330 (PIK3CA)
   04370 VEGF signaling pathway
    125438330 (PIK3CA)
   04068 FoxO signaling pathway
    125438330 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    125438330 (PIK3CA)
   04150 mTOR signaling pathway
    125438330 (PIK3CA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    125438330 (PIK3CA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    125438330 (PIK3CA)
  09143 Cell growth and death
   04210 Apoptosis
    125438330 (PIK3CA)
   04218 Cellular senescence
    125438330 (PIK3CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125438330 (PIK3CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125438330 (PIK3CA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    125438330 (PIK3CA)
   04625 C-type lectin receptor signaling pathway
    125438330 (PIK3CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    125438330 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    125438330 (PIK3CA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    125438330 (PIK3CA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125438330 (PIK3CA)
   05100 Bacterial invasion of epithelial cells
    125438330 (PIK3CA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:stow04131]
    125438330 (PIK3CA)
Enzymes [BR:stow01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     125438330 (PIK3CA)
Membrane trafficking [BR:stow04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    125438330 (PIK3CA)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B DUF2321 Ferritin ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 125438330
NCBI-ProteinID: XP_048362669
LinkDB
Position
LG08:complement(99003171..99048899)
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESTPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
NFTMPSYSRRISTATPYMNGEASAKSLWVINSNLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEEHANWTISRELGYNYNPAAQSSRIARDNELGDSDKEQLRSLCTRDPL
SEITEQEKDFLWRHRHYCVNMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPPIRPEQAME
LLDCNYPDRMVRAFAVRCLEKFLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHAITIFVKLLSRGWVPECKLQSVCDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccagaccatcctctggtgaactgtggggcatccacttgatgccccctagaatt
ctagtagaatgtcttctacctaatggtatgatagtgactttagaatgcctccgtgaggcc
accttgttaaatattaaacatgaactctttaaagaagctagaaaataccctctctaccag
ctccttcaagatgagtcgtcttacattttcgtaagtgttacccaagaagcggaaagagaa
gaatttttcgatgaaactcggagattatgtgacctgcggctctttcagccttttctgaaa
gtcatagagccagtcggcaacagagaagaaaaaattctgaatcgtgaaattggttttgct
attggcatgcctatctgtgaatttgacttggttaaagatccggaagttcaggacttcaga
aggaacattctgaatgtgtgtaaagaagcagtagatcttcgagacgctaacgcaccccat
agtagagcactatacgtctgtccccccaacatagaatcaacgcctgaattgcccaagcat
atatacaataaactagataaaggtcaaataatagtagttatctgggtaatagtctctccc
aataatgacaagcagaaatacaccttgaaaatcaaccatgactatgtgccagagcaagta
atcgcagaagcaatcaggaaaaagacccggagtatgttactgtcgtcggagcagctaaag
ctttgcgttttggaatatcagggaaagtacattttaaaagtgtgtggttgtgatgaatac
ctgctagaaaaacaccccttgagtcagtataagtacatccgaagttgtatcatgcttggt
cgaatgcccaacctcatgctgatggcaaaggaaagcctttacacccagctgcccttggat
aactttacgatgccatcttactcccggcgtatctccacagcgacgccgtacatgaatggt
gaagcttcagccaaatctctctgggttattaacagcaatctcagaataagaattctctgt
gctacctatgtaaatgtaaatattcgagacattgacaagatctatgtccgaactggtatc
taccatggaggagaacctttgtgtgataatgtgaatactcagagagtaccttgctctaat
cccaggtggaatgaatggctgcagtatgagatgcatattcttgatcttccacgtgctgct
cggctttgcctttctatctgctcagttaaaggtagaaagggtgcaaaggaggagcactgc
ccattggcgtgggggaacattaacatgtttgattacacagacactcttgtttctggcaaa
atggctctcaatctgtggcctgtacctcatggtctggaagacctcctaaatcccattgga
gttactggatcaaatccaaataaagaaactccatgcctagagctagaatttgattggttt
agcagccctgtaaagtttcctgacatgtcagtaattgaagaacatgccaactggactatc
tctcgagaactcggctataactataatcctgctgcgcagagcagtagaatagctagagac
aacgagctgggcgacagcgacaaagagcaactccgttcactttgtactcgggatcccctg
tctgaaataactgaacaagagaaggacttcctatggaggcacaggcattattgtgtaaat
atgccagaaattctacctaagctgcttttgtctgtaaagtggaactctagagatgaagta
gcccagatgtactgcttgatcaaagactggcctcccatcaggcctgagcaggcgatggag
cttttggactgtaattatcccgatcggatggtgcgtgcttttgcagtgcggtgtctggaa
aagttcttgacagatgacaagctgtctcagtatttgattcagctggtgcaggttctgaaa
tatgaacagtacttggataatctgttggtaaggtttttactgaagaaggcgttgaccaat
cagagaatagggcatttcttcttttggcatctaaagtctgaaatgcacaataaaaatgtg
agccagaggtttggtctgctcttggaatcctactgccgagcatgtggcatgtacttaaaa
cacctgagcaggcaggtagaagccatggagaaactgattaacctcactgatatcctgaaa
caagagaaaaaggatgaaacgcaaaaggtacaaatgaagttccttgtggagcaaatgagg
cggccagactttatggatgccttgcagggctttatatctcctctgaatcctgctcatcag
cttggaacccttcggcttgaggagtgcaggatcatgtcgtctgcaaaaaggccgttgtgg
ctcaattgggaaaacccagatattatgtctgagctgctgtttcagaacaacgagatcatc
ttcaaaaatggggatgatctacgtcaagatatgctcacgcttcaaataattcgaattatg
gaaaatatctggcagaatcaaggccttgatcttaggatgcttccttatggttgtttatca
atcggagactgtgtgggactcattgaagttgtgagaaattcacacacaatcatgcagatt
cagtgcaaaggtggccttaaaggcgccctgcagttcaacagtcacgcgttacatcagtgg
ctcaaagataagaacaaaggggaaatgtacgatgcagctattgatttgtttacacgctct
tgtgctggctattgtgtggcaacttttatactgggaattggtgatcgtcacaatagcaat
atcatggtgaaagatgacgggcagctgtttcacattgattttggacatttcttggatcac
aagaagaagaagtttggatacaagcgtgagcgggtaccctttgtcttaacacaagatttc
ttgatagtgattagcaaaggagcccaagaatgtaccaaaaccagggaatttgaaaggttt
caagaaatgtgttacaaggcttacttagcaatccggcagcacgccataactatcttcgtc
aagctactctcccgcggctgggttccggaatgcaaattacagtccgtttgtgatattgcg
tatatccggaagacactggcactggacaaaactgagcaggaagcacttgagtatttcatg
aagcagatgaacgatgctcatcatggcggctggacgacaaaaatggactggatcttccac
acaatcaagcagcacgctttgaactga

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