Sphaerodactylus townsendi (Townsend's least gecko): 125442187
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Entry
125442187 CDS
T08213
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
stow
Sphaerodactylus townsendi (Townsend's least gecko)
Brite
KEGG Orthology (KO) [BR:
stow00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
stow01002
]
125442187 (BACE1)
Enzymes [BR:
stow01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
125442187 (BACE1)
Peptidases and inhibitors [BR:
stow01002
]
Aspartic peptidases
Family A1: pepsin family
125442187 (BACE1)
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_N
TAXi_C
Motif
Other DBs
NCBI-GeneID:
125442187
NCBI-ProteinID:
XP_048369340
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Position
LG12:complement(25462645..25484425)
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AA seq
506 aa
AA seq
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MARTPPLLLLLLLLLVLCAASGGRPDGLRLPLRGGGGGRGAAAQEGRARRAAGAEGPVEQ
GRPRSSFVGMIDNLRGKSGQGYYVEMTVGSPPQKLNILVDTGSSNFAVGAAPHPFLKRYY
RHQLSSTFRDLRKGVYVPYTQGKWEGELGTDLVTIPHGPNVTVRANIAAITESDKFFING
SNWEGILGLAYAEIARPDDTLEPFFDSLVKQTRVPNVFSLQLCGAGFPPNNSEALATVGG
SMIIGGIDTSLYTGSLWYTPVRKEWYYEVVIVKMEINGQDLRLDCKEYNYDKSIVDSGTT
NLRLPKKVFEAAVKSIKTASATEKFPDGFWLGEQLVCWQMGTTPWHIFPVISLYLKGETT
NQSFRISILPQQYLRPVEDVATSQDECYKFAISRMRSWLMEGFYCHLGSRASRARRNVGF
AVSSCHVHDEFRTATVDGPFLHPNIEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCL
MVSQWRCLRCLRRSHDDFADDISLLK
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
atggcccgcacgccgccgctgctgctgctgctgctgctgctgctggtgctgtgcgcggcg
tccggcgggcggcccgacgggctgcggctgcccctgcgcgggggcggcgggggtcgcggg
gctgcggcgcaggagggccgggcgcggcgggcggcgggggcggagggccctgtggagcag
ggccgcccgcggagcagcttcgtgggcatgatcgacaacttgcggggcaagtccggccaa
ggctactacgtggagatgacggtgggcagcccgccccagaagttgaatattctggtggac
acggggagcagtaactttgccgtgggtgcagccccacaccccttcttgaagcggtactat
cggcaccagctctccagtaccttccgggacctgcggaagggggtctatgtgccatacact
caagggaagtgggaaggagaactcggcactgacctggtcaccattccacatggcccgaat
gtcacggtccgggcgaacatcgctgccatcacagagtcagacaagtttttcatcaacggc
tccaactgggaagggatcctgggcttggcgtatgcggagattgcccggccagatgacacg
ctggagcccttctttgactcgctggtgaagcagacgcgggtgcccaatgtcttctccctg
caactgtgtggggctggtttcccacccaataactccgaggccctggccactgtggggggc
agcatgatcattggggggatcgatacctctctctatacgggcagcctctggtacacaccg
gtgcggaaggaatggtactatgaagtggtcatcgtgaagatggagatcaatgggcaggac
ctccgcctggactgcaaggagtataactacgacaagagcatcgtggacagcggaaccacc
aaccttcggctgcccaagaaggtctttgaggcagccgtgaaatccatcaagactgcctct
gcgacagagaagtttcctgacggcttctggctgggggagcagctggtctgctggcaaatg
ggcactaccccgtggcatatcttcccagttatctccctgtacctgaagggcgagaccacc
aaccagtccttccggatcagcattctgccccagcaatacctgcggccggtggaggacgtg
gccacctctcaggacgaatgctacaagtttgccatctcaagaatgcgaagttggctcatg
gagggcttctactgccatcttggatcgcgtgcctctcgggcgaggcgaaatgtcggcttt
gccgtcagctcctgccatgttcatgatgagttccggacagccaccgtggatgggcccttc
ctgcaccccaacatcgaggactgcggctacaacattccccagacggacgagtccacgctg
atgaccatcgcctacgtcatggccgcgatctgcgccctcttcatgctgccgctctgcctc
atggtctcacagtggcgctgcctgcgctgcttgcgccgcagccacgacgactttgcggac
gacatctccttgctcaagtga
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