Streptomyces sp. PBH53: QR97_02520 Help Entry QR97_02520        CDS       T10303                                  Name (GenBank) peptide synthetase Organism stpb  Streptomyces sp. PBH53 SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Condensation AMP-binding PP-binding AMP-binding_C Motif Other DBs NCBI-ProteinID:  AKN68829 UniProt:  A0A0H4C2C3 LinkDB All DBs Position 585723..605621 Genome browser AA seq 6632 aa AA seqDB search MTSSTPSNPSNPAQPAGSGRPSRRDRAEALPEELREALRRRLAGRAGGAAPAARQGIPRA DRSRPLPLSFAQARLWFLDRLRPGDPRYNSAVAVRLTGALDHAALREALTAVVARHEALR TTFEEADGRPAQRVHPAGPVPLPVRDTGDLDADLRAEYARPFDLEHGPLLRALLLRESGT AHVLLLTAHHIVTDGWSMGVVLDELCTAYDALAHGSRPDLPPPATQYPDFAVWQRRQLSG TRLDEQLAHWKEKLAGAVAPELPLDRPRRGEEATAGAVHTFTVPAALTARLRDLAREQHS TLHTALVAAVQALLARWSGQDDITVGSLTPGRSRTDLERTVGFFVNTVALRTPVDASGSF RELLARAAGTVGDALAHGDTPFERIVEAVGAPREAGRNPLFDVMVLLHPDPPAATAPRGL ATTPVTVPRQAATFDLSIEFVPDGAALTGLLEYRTDLFDPATAERLAGQLLRLLEGAVDA PDRPLGSLPLLSGDEIRRVVHDWSAGPRLPEDDTVHPEIFERRAARTPDALALVAGGERL DYATLNARANRLAHHLIALGAGPERLVALRLPRTADMIVAILAVWKSGAGYLPLDPALPA ERVRYLLDDARPALVLDEAALRAVPATAPDTDPTDADRRAPLHPEHTAYVIHTSGSTGRP KGVAVSHRAAAHLLAAHRAGFVAEAGGGPLRVALTASFSFDTSLEGVLLMADGHPLHLVD ETTRMDPAALVEYVVAHRVDFLDVTPSYLRQLLPAGLLTDPRHRPRVLMLGGEAVGPALW RELAAHPEVTAHNFYGPTECTVDALSCRIDGGDRPLVGRPLPGVRAYVLDDRLQPVPPGV GGELYLAGAQLARGYTGRPGLTAARFLADPYGPPGTRMYRTGDLARWTSDGRLDYLGRAD DQVKVRGHRIEPGEIEAALLDQPGLTAAAVVAVPDAHGHTRLAAYVVPAPGAARPDPAEL RAALRRTLPDAWVPASFTPLTALPLTSSGKLDRRALPAPESPAQEREFTAPRTPEEETLA AIWAEVLGVDRVGVTDNFFELGGDSILSIQAVSRARAAGLRIGSQDVFRHQTVADLAAAA AHRTTAPAAPRRPHEDGPAPLTPVQEWFLATHGPLRHFSMSMLLDLPHDLDERALERALE ALVARHPALRTRFTRTAGTWRQHPGTGPATGLLTRHGPGTAPDEAAEAARAALDPATGAL FRAALLTGGQRPQLFLTAHHLAVDSVSWRVLLAGLEQAYRQAVAGEEPRPEPEHTPFADW ARALAERVRAGDLDDDLPHWTRETALPRTPLPVDLPGTPLAGSVRTVRTRLDRATTQALL RRVPPVYRTQVNDVLLSALARVLADWTGTDRVTVALEGHGREEELAEGTDLARTVGWFTT QYPVTLTPAGPADWGATLKAVKERLRAVPRRGLSYQALGHLGSPDPAARVLGALPLPQVC FTYHGQWEAPAGGDFAPVADVPGRDTDPGAPLDHLLDVSALVADGELVLTWHYSDQVHRA GTVRRLADGMVRALAAIAEHCARPGAGGRTPSDFPLARLDQAGVDRLAGDGRDVEDLLPL TPLQEGMLFHRLVGGPDDVYVDQAALLLEGVTDPDALAVAWQRVTDRTPALRTSVVWQDV PVPLQVVHRHVTVPVRQLDWREPDAGERAGRLERLRADDLARGLDLGEAPLMRLTLIRLP EDRLHLLWTSHHLILDGWSLAQVLTDVCAEYAALTTGTAPRPPARRPFGDYVRWLAGQDT EAARAHWRTVLAGFATPTPLPADRVRPRGHETRSGHVHTAGLSDAVSARLARTARAAGLT LGTVVQGAWALLLSRYSAEPDVLFGTTVSGRPDDLPGVESMVGMFINTLPTRVRVDGGRT ATAWLRELQEAQAEARRFAAVSLAELTTLSDVPAGTPLFDSMVAFENYPFDQARSAGTGI RLADVSARDATNYPLVLRAYQGERFGFDLAYDPELFDATTVRSLADRLCLLLTELADDPD RPVRALAWTTAEERRRILADGNGTEAGRPADTLDALFAAQAARTPHAEAVSCGEDRLDYA TLDARAGRLAHRLAELGAAPEKFVALALPRSTDLVVAVLAVLKTGAAYLPIDPALPAERV RQLLADTGPVALVTTTTGTAAGTAVPLLPLDDPAVRADLERRPAAGPAPRALPESPAYAI YTSGSTGRPKGVVVPHANVVRLFTRTRHWFGFGPDDVWTLFHSYAFDFSVWELWGPLLHG GRLVIVPEDTARSPEDFLRLLADEQVTVLNQTPSAFYPLSRTDAELPDVSARLALRTVIF GGEALDVSRLADWYTRHPDTAPRLVNMYGITETTVHVTYAPLDRRAARAGTASPIGTGIP DLRVHVLDDTLRPVPPGAVGELFVAGEGLARGYLNRPGLTAARFLADPYGTPGTRMYRTG DRARRRADGTLEYLGRADQQVKIRGYRIEPGEIEAALHSHPGVGAAAVGVYEDAGGTRRL VAHVVGTGTGDRAAPLPPAAELRAHLARSLPAHMVPAAYVPLAALPLTANGKLDRRALPA PGPDGFAADGTRTPLRTPAERLVAAAWTDVLDTDEVGADDDFFALGGDSILAVRVTSRLR TAFGTDVSPRLLFTHSTLSALAAALAGPRAVHSAGTIPAAAPDAPAPLSYAQQRLWFLDR FEPGSTEYTTLSVLRLRGPLDTAALRTALDGLVARHASLRTTFAEHDGQARQFVHPPRPV DLPVDDLADTAALDALLDREAATPFDLTTGPLFRARLARLGAEEHVLVLAAHHIVTDGWS TGVLARDLGELYTAAREERRPDLPEPPVRYTDYATWQRTRTEQHESGLAYWRGALDGVTP LELPTDRPRPAVRTRDGALVTFTLPAALTERLRERGRESDATLYMTLVAACQVLLARWAG QEDVTVGTVTAGRERPELHDLVGMFVNTLVLRARVRPDLPFRELLGEVRTTVLEAFAHQE VPFERVVDALQPERDTSRTPLFQVMVALHNLGAEPPRLPGLTVEPLTPPVRSAGYDLAFD FVETDGGLTGHLEYSTGLFDADTAERLAARLRVLLEAAAEDPALPVGRLPLMTGAERRLV LRYGQGARLPEPDTTFPALFQAQAARTPHHTALVARDTTLDFAALNRRANRLAHHLIARG AGPEDVVAVRLPRTSDLMTALLAVLKAGATLLCLDPALPPERQDLLLADARPHTLLTGLD AVPWDRLPDRDPTDTDRIRPLLPRHTAYIVYTSGSTGRPKGVAVEHRQLVNLCHDHRAGL LAPHTARGERLRAALSASFSFDTSWEGPLLLALGHEVHLVDEDVRLDPEAFCAQVAEDRL DLVNVTPSFLRELTAAGLLAPGRHHPRLLLVGGEAVTAADWRDLVRAERELGVAVYNMYG PTECTVDAVYGRAGDRPDRPALGRPGGNLRALVLDGALRPVPPGVPGELYLAGDQVARGY LHRPGLTAARFLADPFGAPGERMYRTGDRVRWDRDGRLEFLGRVDEQVKIRGFRIEPGEV EAALLDHPDIADAAVAAREHAGRRMLVGYLVPAAGRVPSADALRLALRRTLPDHMVPAAF VPLARIPRTPSGKTDRRALPAPPAQPDSATPYVAPRPGPEERLAAIWAQVLGVERVGARD NFFSLGGDSILSIQIVSRARQAGLALTTKDVFRHQTVAELALCATESAPPPAAAEETGEA PLTPIQRWYLDGRDGARRLRFTMTQRLELAAGTDPTALRRATDAVVRHHPALRTRFRRTA EGWRQEVLPEAPDGVLTRHDVTGRADAALEAEVQRLTDEAQAGLDPVAGRVVRVLHVDRG PRLPGQLVVTAHHLVIDGVSWRILLADLETAYRDAAAGRPVELPATGTSYGQWAARLDRH TRSGALDGDLPYWTRTGAAPAELPAGRPGPNTHGTAATLTVTLDEQATDALLRQVPETYR TQVNDVLLSALGRTLARWCGRDTVLLGVEGHGREDLFDDVDLARTVGWFTAEFPLALRVD PDAGWRDTLRAVKEQLRAVPLHGLSHGALRHLRPDSPLAGAPAPRVGFNYHGQWDAGGTG TGGLFLGSLPPAGRDTDPDEPRPYLLDITGVVQQGRLELGWTYPAAVYDEATVRRLAEET VTALRDIVAHCARPDAGGRTPSDFPLAGLDQDRLDRLVGAGRHVEDVLPLTPLQSGMLFH GLVDTEHAYFDRTAVRLAGVADPRAFAAAWQQVADRTPALRTSVHWQGLPQPVQVVHRRA ELPVTHLDWRALTPAQRAEATERLLAEDRAAGMDLTTPPLTRLTLAALPGDEVLLLWSTH HIVLDGWSTGQLLTEVCERYAALTGGPDPAPPVRRPFADFLHWLRAQDETAAERHWADAL AGFTARTPLPYDRTPAEAHRARSAAAVHRELDARISGRLRETAARAGLTVNTVVEGAWAL LLARYSGRDDVVFGTTVSGRPAELPGVEGMIGMFINTVPTRVRVPDGPVLPWLRGLQDRQ SDARRFDFLALPRIQAVSDVPSGEPLFDSMVVFENYPVDESATARTGVRVEEVRADDATT FPWALRAHLAGRLGFDLAYDPALFDPGTAERAADRLAALLTALADGFDTDLAGLDLLTPA DRDLLAAWNTTARPAAPASPVDLFAEQARRTPDALAVQDGDRELTYRHLAEWADALAGRL VAGGLAAEDRVALLMDRSAELVVAQLAVLQAGGAYVPVDTRAPEDRRRTLLAQAGATVRL TAADVTAARIGTGTTTERTPAADPDRLAYVMFTSGSTGLPKAVAVRHRDVAALATDSRFA DGVCARVLLHSPVAFDAATFEVWAPLLAGGCVVVAPGESVDAALLRRLAADGGLTALWLT AGLFRLLAQDTPDCFRGLAQVWTGGDVVPAQAVRRVLAACPGLTVVDGYGPTETTTFATS FALTDPAAVPGTVPIGRPLDDMRAHVLDARLRPVPPGCAGELYLAGEGVARGYLGRPGDT AARFLADPAGPPGARMYRTGDLARRRPDGTVEFLGRADDQVKIRGFRVEPGEVEAVLAAH PDVVDVAVLAREDRPGAKRLVAYVVGPAGQDGEELRAFAARTLPDYLVPTAVVPLPALPL SRNGKLDRAALPAPEALPGRTRVEPRTEAERRTAAVFGEVLGSEPPGVEDDFFQLGGDSI LSIRLASRLAETFDTDLSPRAVFTHPTPAGLAGLLGARQGTGRAALTPVTRNGAAPMSYA QQRLWFLEEFAPGGTEYVTALALRLRGTLDAGALRAALAALVARHESLRTTFDSVDGHGV QLVHPPQEVPLPVRDLSSLRDSAREPALRSLLAEERARPFDLREGPLLRTGLVRLAERDH VLTLTLHHIVTDGWSTAVLLGDLAHLYRAELGAAEDQLPPLPVQYADYAHWQRTAAATGL DEHLAYWKRHLADTAPLDLPTDRPRPPVRTSSGATTRLLVPARTARRLDRLARRHGTTLF TTLVAAAQAYLARLSGAEDITVGTVSSGRDRPETQGLVGFFVNTLVLRSRAEAEQPFTGF LTAVRQTVLDAFAHQDVPFERVVDEVDPVRDTSRTPLFQVMVVLQNTPAAALDLPGLDVT DVEPESEQAPFDLTLEFAETGDGALHGLLTYNTDLFDAATAERMAGQLGTLLHAVAEDPD RPLGALPLTSDDELKTVLEQGRPTFRPVPEATLPALFERQAARTPDAVALVDGDRERTYA DVDRAANRLAHRLLRDGVGPERVVALALPRSAAAVVAQLAVAKAGGAFLPVDPDYPPQRR EFMIRDAGAHLVLADPAEVWAADGPDTAPTDADRPTALTPAHPAYVIYTSGSTGTPKGVV VTHRGLASFAAAAAEQYAAGPGDRVLQFASPSFDASVLELCVSLLGGAALVTGEEGPLVG ERLAEVLAERRISHTLIPPAALATVPPGTAAALPHLRTLIVGAEACPADLVDTWAPGRRM INSYGPTEATVVATWTGPLTPGTGTPPIGRPAAGTRVRVLDAALRPVPPGVTGELYLAGP GLARGYLGRPGLTAQRFVADPFGAPGERMYRTGDLVRWTADGRLVFAGRADDQVKLRGFR IEPGEIESALRRSPLVRDAVVAVRAEDTPGAPARLVAYVVPAQASGTALPVAELRLHLAG LLPPHMVPAVFVPLDRLPLTPNGKTDRRALPAPGPVPAGDGPRTAPRTDTERRIARIWAD VLGIEEVGAEDNFFALGGDSVLSMQVVSRLRRDGLHVATRDLFTHQTVAELATVVRTAPR RTGDGPVTGEVPLTPIQDWFLTTPRAAHHHFNQSVLLELAETPDPRALRTALDALLDHHD ALRMRFTRDADGWHQFNPPPATGYDLLVRHDLTGLSAEEADTAMAKAADELHAGFDLARG PQLRAALFTGDSDRPAYLLLVAHHLVVDAVSWRILRDDLETAYRQARQGDPVALGERGTS FRDWSRGLAGYVAEGGLDHELPYWEQAVRTQEAPAPAPGTGPAATVSVELGEEDTTALLR AAPTAYRTRVNDVLLAALALALARWTGRDRVRLDLEGHGREDLLDGVDLSRTVGWFTTVY PVALQVPDPGDLGPERDWRSLVKSVRRQLRAVPGNGLGFGALRTFGPPEVRARLGGSAHS EVVFNYLGQWDARPETATGGLVRAEHGSFGQDHDPRDPGSHLLEVVGAVQHGRLAFTWHH RPGVHDTATVRRVAEEFAAALRHLARHARGGR NT seq 19899 nt NT seq  +upstreamnt  +downstreamnt atgacgtcttcgaccccttcgaacccctcgaaccccgcgcagcccgccggctccgggcgg ccctcccggcgggaccgcgccgaggcgctgcccgaggagctgcgggaggcgctgcgccgg cggctggccggacgggccggcggtgcggcaccggccgcccggcagggcatcccgcgcgcc gaccggagccgcccgctgccgctgtccttcgcgcaggcgcggctgtggttcctggaccgg ctgcgccccggcgacccccgctacaacagcgcggtcgcggtccgcctcaccggcgcgctg gaccacgcggccctgcgggaggccctcaccgccgtcgtcgcccggcacgaggccctgcgc accaccttcgaggaggccgacggccgcccggcgcagcgcgtgcacccggcgggcccggtg ccgctgccggtccgggacaccggtgacctggacgcggacctgcgggccgagtacgcccgc cccttcgacctggagcacgggccgctgctgcgcgccctgctgctgcgcgagtccggcacc gcgcacgtgctgctgctgacggcccatcacatcgtcacggacggctggtcgatgggcgtg gtcctggacgagctgtgcaccgcctacgacgccctcgcccacggctcccggccggacctg cccccgccggccacgcagtacccggacttcgcggtgtggcagcgccggcagctgtcgggc acccgcctcgacgagcaactcgcccactggaaggagaaactggccggtgcggtggctccg gagctgcccctggaccggccccggcgcggcgaggaggcgaccgcgggcgccgtgcacacc ttcaccgtccccgccgccctcaccgcccggctgcgcgacctcgcgcgagagcagcacagc accctgcacaccgccctggtcgccgccgtccaggcgctgctggcccgctggtccggccag gacgacatcaccgtcggctccctgacccccggccggtcccgcaccgacctcgaacggacc gtcgggttcttcgtgaacacggtcgcgctgcgcaccccggtggacgcctccggttccttc cgcgagctgctggcgcgggcggccggcacggtgggcgacgccctcgcgcacggcgacacg ccgttcgagcggatcgtggaggcggtgggcgcaccccgcgaggcgggccgcaacccgctg ttcgacgtgatggtcctgctgcaccccgacccgcccgccgcgaccgccccgcgcggactc gccaccaccccggtcaccgtcccccggcaggccgccaccttcgacctgagcatcgagttc gtgccggacggcgcggcgctgaccgggctgctggagtaccgcaccgacctgttcgacccc gccacggccgagcggctggccggacagctgctgcgcctgctggagggcgccgtcgacgcc ccggaccgcccgctgggcagcctgcccctgctgtccggcgacgagatacggcgtgtcgtc cacgactggagcgccggaccgcggctccccgaggacgacaccgtccacccggagatcttc gagcgccgcgcggcccgcacgcccgacgcgctcgccctcgtcgcgggcggcgaacggctg gactacgccacgctcaacgcccgcgccaaccggctcgcccaccacctcatcgcgctcggc gccggccccgagcggctggtggcgctgcggctcccgcgcacggcggacatgatcgtcgcg atcctcgccgtctggaagtccggcgccggctacctgccgctggacccggccctgcccgcc gaacgcgtccgatacctgctggacgacgcccgcccggccctcgtcctggacgaggccgcc ctgcgcgccgtacccgcgaccgccccggacaccgaccccaccgacgccgaccggcgcgcc ccgctgcaccccgagcacaccgcgtacgtcatccacacctccggctccaccggccgcccc aagggcgtcgccgtgtcccaccgtgcggcggcgcacctgctggccgcgcaccgggccggg ttcgtcgccgaggcgggcggcggcccgctgcgcgtcgcgctcaccgcgtccttctccttc gacacctccctcgaaggcgtgctcctgatggccgacggccacccgctgcacctggtcgac gagacgacccggatggacccggccgccctggtggagtacgtcgtcgcgcaccgcgtcgac ttcctcgacgtcaccccctcctacctgcggcaactgctgcccgccggactgctcaccgac ccccggcaccgcccccgggtgctcatgctcggcggcgaggcggtcgggcccgcgctctgg cgcgaactggccgcccaccccgaggtgaccgcccacaacttctacggccccaccgagtgc acggtcgacgcgctgtcctgccgtatcgacggcggcgaccgcccgctggtgggccgcccc ctgccgggcgtgcgggcctatgtgctggacgaccggctccagccggtgccgcccggcgtc ggcggcgagctgtacctcgcgggcgcccagctggcccgcggctacaccggccgccccggc ctgaccgccgcccgcttcctcgccgacccctacgggccgcccggcacccgcatgtaccgc accggcgacttggcccgctggacctccgacggccgcctcgactacctcggccgcgccgac gaccaggtcaaggtgcgcggccaccgcatcgaacccggcgagatcgaggccgccctgctc gaccagcccggcctcaccgccgccgcggtcgtcgccgtacccgacgcacacggccacacc cgcctcgccgcctacgtcgtccccgcgcccggcgcggcccggcccgaccccgccgagctg cgcgcggccctgcgccgcaccctgccggacgcctgggtgcccgcctccttcaccccgctg accgcgctcccgctgaccagcagcggcaaactggaccgccgcgccctgcccgcgcccgag agccccgcgcaggagcgggagttcacagccccgcgcacccccgaggaggagacgctcgcc gccatctgggccgaggtgctcggcgtggaccgggtgggcgtcacggacaacttcttcgag ctgggcggcgactcgatcctgagcatccaggccgtctcccgggcccgcgccgccggtctg cggatcggctcccaggacgtcttccggcaccagacggtcgccgacctggccgccgccgcg gcccaccgcaccaccgcgccggccgcgccccggcgcccgcacgaggacgggcccgccccg ctcaccccggtgcaggagtggttcctcgccacgcacggcccgctgcggcacttcagcatg tcgatgctgctcgacctgccgcacgacctcgacgagcgggcgctggaacgggcgctggag gccctggtggcccggcatccggcactgcgcacccgcttcacccgcaccgccggcacctgg cggcagcaccccggcaccggcccggccaccggactgctcacccgccacggccccggcacc gcacccgacgaggccgccgaggccgcccgcgcggccctggacccggccaccggcgcgttg ttccgcgccgccctgctcaccggcggacagcgcccgcaactgttcctgaccgcccaccac ctggcggtcgacagcgtgtcctggcgggtgctgctggccggcctggagcaggcctaccgg caggccgtcgcgggggaggagccccggccggagcccgagcacacccccttcgccgactgg gcacgcgccctggccgagcgggtgcgggccggcgacctggacgacgacctgccccactgg acgcgggagaccgcgctgccccgcaccccgctccccgtcgacctccccggcaccccgctc gccggatccgtgcgcaccgtccgcacccgcctggaccgcgccaccacgcaggccctgctg cgccgcgtgccccccgtctaccgcacccaggtcaacgacgtgctgctgagcgcgctggcc cgggtgctggcggactggaccggcacggaccgggtgaccgtcgccctggagggccacggc cgggaggaggagctggccgagggcaccgatctggcccgcacggtcggctggttcaccacc cagtacccggtcaccctgaccccggccggccccgccgactggggtgccacgctcaaggcc gtcaaggaacggctgcgagccgtgccccgccgcggcctgagctaccaggcactgggccac ctcggctcgcccgacccggccgcgcgggtcctcggcgcactcccgctgccccaggtgtgc ttcacctaccacggtcagtgggaggcgcccgccggaggggacttcgcgcccgtcgccgac gtacccggccgggacaccgaccccggggccccgctggaccacctcctcgacgtctccgcc ctggtcgccgacggcgaactggtcctcacctggcactacagcgaccaggtgcaccgggcc ggcaccgtccggcggctggccgacggcatggtgcgcgcgctcgccgccatcgccgagcac tgcgcccggcccggagcgggcggccgtaccccctccgacttcccgctcgcgcgcctggac caggccggcgtggaccgcctcgccggcgacggccgggacgtggaggacctgctgccgctc accccgctccaggagggcatgctcttccaccggctggtcggcggaccggacgacgtgtac gtcgaccaggccgcgctgctgctggagggggtgaccgaccccgacgccctggccgtggcc tggcagcgggtgaccgaccgcacccccgccctgcgcacctcggtggtgtggcaggacgtg ccggtgccgctccaggtcgtgcaccgccacgtcaccgtgcccgtgcggcagctggactgg cgggagccggacgcgggggagcgggccggacggctggagcggctgcgcgccgacgacctc gcccgcggcctggacctcggcgaggcccccctgatgcggctgaccctgatccggctgccc gaggaccggctgcacctgctgtggacctcccaccatctgatcctggacggctggagcctg gcccaggtgctcaccgacgtgtgcgcggagtacgcggccctcaccacgggcaccgcgccc cggcccccggcccggcggccgttcggcgactatgtgcgctggctggccggccaggacacc gaggccgcccgcgcccactggcggaccgtcctcgccgggttcgccacccccaccccgctg cccgccgaccgcgtccgcccccggggccacgagacccgctccgggcacgtgcacaccgcc gggctgtccgacgcggtctcggcgcggctggcccgcaccgcccgcgcggccggactgacc ctcggcaccgtcgtgcagggcgcctgggcgctgctgctgtcccgctacagcgccgagccc gacgtgctgttcgggaccaccgtctccggacgccccgacgacctgcccggcgtcgagtcg atggtcggcatgttcatcaacaccctgcccacccgcgtccgcgtggacggcggccgtacc gccaccgcctggctccgcgaactgcaggaggcgcaggccgaggcgcggcggttcgcggcg gtgtccctcgccgaactcaccacgctgagcgacgtgcccgccggcaccccgctgttcgac agcatggtggccttcgagaactaccccttcgaccaggcccgctcggccggcaccgggata cgcctcgcggacgtctccgcccgcgacgccaccaactaccccctggtgctgcgggcctac cagggcgagcggttcggcttcgacctcgcctacgaccccgagctgttcgacgccaccacg gtacggagcctcgccgaccggctgtgcctgctgctcaccgagctggccgacgacccggac cggcccgtgcgcgccctcgcctggacgaccgccgaggaacggcggcggatcctggccgac ggcaacggcaccgaggcgggccgccccgccgacaccctggacgccctcttcgcggcccag gccgcccgcaccccccacgccgaggccgtcagctgcggcgaggaccggctcgactacgcc accctggacgcacgggccggccggctcgcccaccggctcgccgaactcggcgccgcaccc gagaagttcgtggcgctcgcgctgccccgctcgaccgacctcgtcgtggccgtcctcgcc gtcctcaagaccggcgccgcctacctgcccatcgaccccgcgctgcccgccgaacgcgtc cggcagctgctcgccgacaccggcccggtggcactggtgaccaccaccacggggacggcg gccggaaccgccgtaccgctcctgccgctggacgaccccgcagtccgggccgacctggag cggcgcccggccgccggaccggcgccccgcgccctgccggagagccccgcctacgccatc tacacctccggctccaccggccggcccaagggcgtcgtcgtcccgcacgccaacgtcgtc cggctgttcacccgcacccggcactggttcggcttcggccccgacgacgtgtggacgctg ttccactcctacgccttcgacttctcggtgtgggagctgtggggcccgctgctgcacggc ggccggctcgtgatcgtccccgaggacaccgcccgctccccggaggacttcctgcggctg ctcgccgacgaacaggtcaccgtcctcaaccagaccccgtccgccttctacccgctgagc cggacggacgccgaactccccgacgtcagcgcgcggctggcgctgcgcacggtgatcttc ggcggcgaggcgctggacgtcagccggctcgccgactggtacacccgccacccggacacc gcgccccgcctggtcaacatgtacggcatcaccgagaccaccgtgcatgtcacctacgcc ccgctggaccgccgggcggcccgcgccggcaccgcgagccccatcggcaccggcatcccc gacctgcgggtccacgtcctcgacgacacactgcggccggtaccgcccggcgccgtcggc gagctgttcgtcgccggcgagggcctggcgcgcggctacctgaaccggcccggcctcacc gcggcccggttcctcgccgacccctacggcacaccgggcacccgcatgtaccgcaccggg gaccgggcccgccgacgggccgacggcaccctggagtacctgggccgcgccgaccagcag gtgaagatccgcggctaccgcatcgagcccggcgagatcgaggccgccctgcacagccac ccgggcgtgggcgcggcggccgtcggcgtgtacgaggacgccggcgggacccgccggctg gtcgcccacgtcgtcggcaccggcaccggcgaccgcgccgcaccgctgccgcccgccgcc gaactccgcgcccacctggcgcggtcgctgcccgcgcacatggtgccggccgcctatgtg ccgctcgccgccctgccgctcaccgccaacggcaagctcgaccggcgcgccctgcccgcg cccggccccgacggcttcgccgccgacggcacccgcacccccctgcgcaccccggccgaa cgactggtcgccgccgcgtggaccgacgtcctggacaccgacgaggtcggcgccgacgac gacttcttcgccctcggcggcgactccatcctcgccgtccgcgtcacctcccggctgcgc accgccttcggcacggacgtctcgccccggctgctgttcacccactccaccctgtccgcc ctcgcggccgcgctggccggaccccgggccgtgcacagcgccggcacgatcccggccgcc gccccggacgccccggcaccgctgtcgtacgcccagcaacgcctgtggttcctcgaccgg ttcgagccgggcagcaccgagtacaccaccctgtccgtgctgcggctgcgcggcccgctc gacaccgccgccctgcgcaccgccctggacggcctcgtcgcccggcacgcctccctgcgc accacgttcgccgaacacgacggccaggcacggcagttcgtccacccgccgcggcccgtg gacctgccggtggacgacctcgcggacaccgcggccctcgacgccctgctcgaccgcgag gccgccacccccttcgacctcaccaccgggccgctgttccgggcccggctggcccggctc ggagccgaggagcacgtcctcgtcctggccgcgcaccacatcgtcaccgacggctggtcc accggcgtcctggcccgggacctgggcgagctgtacacggcggcccgcgaggaacgccgc cccgacctgcccgagccgcccgtccgctacaccgactacgccacctggcagcgcacccgc accgagcagcacgagagcggactcgcctactggcgcggcgcgttggacggcgtgaccccg ctggagctgccgaccgaccggccccgtccggccgtccgcacccgtgacggcgccctggtg accttcaccctgcccgccgcgctgaccgagcggctgcgcgagcgcggccgggagtccgac gccaccctctacatgaccctggtggcggcctgccaggtgctgctcgcccgctgggccggc caggaggacgtcaccgtcggcaccgtcaccgccggccgcgaacggcccgaactgcacgac ctcgtcggcatgttcgtcaacacgctggtgctgcgcgcccgggtccgccccgacctgccc ttccgggagctgctcggcgaggtgcgcaccaccgtcctggaggcgttcgcccaccaggag gtgcccttcgagcgggtcgtggacgccctccagcccgagcgggacaccagccgcaccccg ctgttccaggtcatggtcgccctgcacaacctcggcgccgaaccgccccggctgcccggc ctgacggtggagccgctgaccccgccggtccgctccgccgggtacgacctcgccttcgac ttcgtggagaccgacggcgggctcaccggccacctggagtacagcaccgggctgttcgac gccgacaccgccgaacgcctggccgcccggctgcgcgtcctgctggaggccgccgccgag gaccccgcgctgcccgtgggccggctgccgctgatgaccggtgccgagcgccggctggtc ctccggtacgggcagggcgcccggctgcccgagccggacaccaccttccccgccctgttc caggcccaggccgcccgcaccccgcaccacaccgccctggtggcccgcgacaccaccctg gacttcgccgcgctgaaccggcgcgccaaccggctcgcccaccatctcatcgcccggggc gccggccccgaggacgtggtcgccgtacggctcccgcgcacctccgacctgatgacggcg ctcctcgcggtcctcaaggcgggcgccaccctgctctgcctggaccccgcactcccgccg gagcggcaggacctcctgctcgccgacgcccggccgcacaccctgctcaccgggctcgac gcggtgccctgggaccggctgcccgaccgggatccgaccgacaccgaccggatccggccc ctgctgccacggcacaccgcgtacatcgtctacacctccggctccaccggccgccccaag ggcgtcgccgtcgaacaccggcagctggtcaacctctgccacgaccaccgcgcgggcctg ctcgccccgcacaccgcccggggggagcggctgcgggccgcgctcagcgcctccttctcc ttcgacacctcctgggaaggacccctgctgctcgccctcggccacgaggtccacctcgtc gacgaggacgtacgcctggacccggaggcgttctgcgcccaggtcgccgaagaccgcctc gacctggtcaacgtcaccccgtccttcctgcgcgaactcaccgccgccggcctgctcgcc cccggccgccaccacccgcggctgctcctcgtcggcggcgaggccgtcaccgcggccgac tggcgcgacctcgtccgcgccgaacgggagctgggcgtggcggtgtacaacatgtacggg cccaccgagtgcaccgtcgacgccgtctacggccgcgccggcgaccggcccgaccgcccc gccctcggccggcccggcggcaacctgcgcgccctcgtgctcgacggcgccctgcgcccg gtgccgcccggggtgcccggcgagctgtacctggccggggaccaggtcgcccgcggctat ctgcaccggcccgggctgaccgccgcccgcttcctcgccgacccgttcggcgcgccgggg gagcggatgtaccgcaccggcgaccgggtccgctgggaccgggacggacggctggagttc ctcggccgggtggacgagcaggtcaagatccgcgggttccgcatcgagcccggcgaggtg gaggccgccctcctggaccacccggacatcgccgacgccgcggtcgccgcacgcgaacac gccggccgccgcatgctcgtcggctacctggtgcccgccgccggccgcgtcccgtccgcc gacgccctgcggctcgcgctgcgccgcaccctgcccgaccacatggtgcccgccgcgttc gtcccgctggcccgcatcccccgcacccccagcggcaagaccgaccggcgcgccctgccc gccccgcccgcccagcccgacagcgccaccccgtacgtcgccccccggcccggcccggag gagcggctggccgcgatctgggcgcaggtgctcggcgtcgaacgggtcggcgcgcgcgac aacttcttctcgctcggcggcgactccatcctcagcatccagatcgtctcccgcgcccgc caggccgggctcgccctcaccaccaaggacgtcttccgccaccagacggtcgccgaactc gccctgtgcgcgacggagtccgccccgcccccggccgccgccgaggagacgggcgaggca ccgctcaccccgatccagcgctggtacctggacggccgcgacggcgcgcggcggctccgc ttcaccatgacccagcgcctcgaactcgccgcgggcaccgaccccacggcgctgcggcgg gccaccgacgccgtcgtacgccaccacccggccctgcgcacccgcttccgccgcaccgcc gagggctggcgccaggaggtgctgcccgaggcgccggacggcgtcctcacccgtcacgac gtgaccgggcgggccgacgcggcactggaggccgaggtccagcggctcacggacgaggcg caggccggtctcgaccccgtcgcgggccgggtcgtccgcgtcctgcacgtcgaccgcggc ccccggcttcccgggcagctcgtcgtcaccgcccaccacctggtgatcgacggagtgtcc tggcgcatcctgctggcggacctggagaccgcgtaccgggacgccgcggccggccggccc gtcgagctgcccgccacgggcacctcctacggccagtgggccgcccgcctcgaccggcac acccgctccggcgccctggacggcgacctgccgtactggacacgcaccggcgcggccccc gccgagctgcccgccggccggcccggcccgaacacccacggcaccgccgccaccctcacg gtcaccctggacgagcaggccaccgacgccctgctgcggcaggtccccgagacctaccgc acccaggtcaacgacgtcctgctcagcgccctcggccgcaccctggcccgctggtgcggg cgcgacacggtcctgctgggcgtggagggacacggccgcgaggacctgttcgacgacgtg gacctcgcgcggaccgtcggctggttcaccgccgagttccccctcgccctgcgcgtcgac ccggacgccggctggcgcgacaccctccgcgcggtcaaggagcagctgcgcgcggtgccg ctgcacggcctgagccacggtgccctgcgccacctgaggcccgacagccccctcgccggc gcaccggccccgcgggtcggcttcaactaccacggccagtgggacgcgggcggcaccggc accggcggactgttcctcggctccctgcccccggccggccgggacaccgaccccgacgaa ccccggccgtacctgctggacatcaccggcgtggtccagcagggccgcctggaactcggc tggacctacccggcggcggtctacgacgaggccaccgtccgccggctcgccgaggagacg gtcaccgccctgcgggacatcgtggcgcactgcgcccgccccgacgcgggcggccgcacc ccctccgacttccccctcgccggcctggaccaggaccggctggaccggctcgtgggcgcc ggccggcacgtcgaggacgtcctgccgctcacccccttgcagtccggcatgctgttccac ggcctggtggacaccgagcacgcctacttcgaccggacggccgtacggctggccggggtg gccgacccgcgcgccttcgccgccgcctggcagcaggtcgccgaccgcaccccggcgctg cgcaccagcgtccactggcagggcctgccccagccggtccaggtcgtccaccggcgcgcc gagctgcccgtcacccacctcgactggcgcgccctgacgcccgcacagcgcgccgaggcc accgagcgcctgctcgccgaggaccgcgcggcgggcatggacctcaccaccccaccgctc acccgcctcaccctggccgccctgcccggcgacgaggtgctgctgctgtggtccacccac cacatcgtcctcgacggctggagcaccgggcagctgctcaccgaggtgtgcgagcggtac gccgccctgaccggcggcccggacccggcacccccggtacggcggcccttcgcggacttc ctgcactggctgcgcgcgcaggacgagacggcggccgaacggcactgggccgacgcgctg gccgggttcaccgcccgcaccccgctgccctacgaccgcacacccgccgaggcccaccgc gcccggtccgccgcggccgtccaccgcgagctggacgcgcggatctcgggccggctgcgg gagaccgccgcccgcgccgggctcaccgtgaacaccgtggtggagggcgcctgggcgctg ctgctggcccgctacagcggccgggacgacgtggtgttcggcaccaccgtctccggccgc ccggccgaactgcccggcgtcgaaggcatgatcggcatgttcatcaacaccgtgccgacc cgggtccgggtccccgacgggccggtgctgccgtggctgcgcggcctccaggaccggcag agcgacgcccgccgcttcgacttcctcgccctgccccgcatccaggccgtcagcgacgtc ccgtccggcgaaccgctgttcgacagcatggtggtgttcgagaactaccccgtggacgag tcggccaccgcccgcacgggcgtccgggtcgaggaggtccgcgccgacgacgccaccacc ttcccgtgggccctgcgcgcccacctggccggacggctgggcttcgacctggcctacgac cccgcgctgttcgaccccggcaccgccgagcgcgccgcggaccggctggccgcgctgctc accgccctcgccgacgggttcgacaccgacctggccggcctggacctgctcacgcccgcc gaccgcgacctgctggccgcctggaacaccaccgcccgcccggccgccccggcgagcccc gtggacctgttcgccgagcaggcccgccgcaccccggacgcgctcgcggtccaggacggc gaccgcgagctgacctaccgccacctcgcggaatgggcggacgccctggcgggacggctg gtggccggcgggctggcggccgaggaccgggtggcactgctgatggaccgctccgccgaa ctcgtcgtcgcccagctcgcggtgctccaggccggcggcgcctacgtccccgtcgacacc cgggcccccgaggaccgccgccgtacgctgctcgcccaggcgggcgcgacggtccggctc accgccgccgacgtgacggccgcccgcatcggcaccggtacgacgacggagcggacaccg gccgccgaccccgaccggctggcgtacgtgatgttcacctccggctccaccggcctgccc aaggcggtcgcggtacggcaccgggacgtggccgcgctggccaccgacagccggttcgcc gacggcgtgtgcgcccgggtgctgctgcattcgccggtggccttcgacgccgccaccttc gaggtgtgggcgccgctcctcgccggcggctgcgtggtcgtggccccgggcgagagcgtg gacgcggccctgctgcgccggctggccgccgacggcggcctgaccgcgctgtggctgacc gccggactgttccggctgctcgcgcaggacacccccgactgcttccggggcctcgcgcag gtgtggaccggcggcgacgtcgtgcccgcccaggcggtgcgccgggtgctggccgcctgc cccggcctgaccgtcgtggacggctacgggcccaccgagaccaccaccttcgccacctcc ttcgccctcaccgacccggccgcggtgcccggcaccgtgcccatcggccggccgctggac gacatgcgggcgcatgtgctcgacgcccggctgcggcccgtaccgcccggctgcgcgggc gagctgtacctggccggcgagggcgtcgcccgcggctacctgggccgccccggcgacacc gccgcccgcttcctcgccgaccccgccggcccgcccggcgcccgcatgtaccgcaccggc gacctggcccggcgtcggccggacggcaccgtcgagttcctgggccgcgccgacgaccag gtgaagatccggggcttccgggtcgaacccggcgaggtcgaggccgtgctcgccgcccac ccggacgtcgtggacgtcgccgtgctcgcccgcgaggaccggccgggcgccaaacggctc gtggcctacgtcgtcggaccggccgggcaggacggcgaggaactgcgggccttcgccgcc cgcaccctgcccgactacctcgtccccaccgccgtcgtcccgctccccgccctcccgctc agccgcaacggcaagctcgaccgggcggccctgcccgcacccgaggccctgccggggcgc acccgggtcgagccccgcaccgaggccgagcgccgcacggccgccgtcttcggcgaggtg ctgggcagcgaaccgcccggtgtggaggacgacttcttccagctcggcggcgactccatc ctcagcatccggctcgcctcccgcctcgccgagacgttcgacaccgacctcagcccgcgc gcggtgttcacccaccccacgcccgccggactggccggcctgctcggcgcacggcagggc accggccgggcggccctcaccccggtcacccggaacggggccgcgcccatgtcgtacgcc cagcaacgcctgtggttcctggaggagttcgcgcccggcggcaccgagtacgtgaccgcg ctcgccctccggctgcgcggcaccctggacgccggcgccctgcgcgccgccctggccgcg ctggtggcccggcacgagtcgctgcgcaccaccttcgacagcgtcgacggacacggcgta cagctcgtccacccgccccaggaggtgccgctgcccgtacgcgacctgtcctccctgcgg gacagcgcacgggaaccggcgctgcggagcctgctcgccgaggaacgcgcccgccccttc gacctgcgcgaagggcccctgctgcgcaccggtctggtccggctcgccgagcgcgaccac gtgctgaccctcaccctgcaccacatcgtcaccgacggctggtcgaccgccgtcctgctc ggcgacctcgcccacctctaccgtgccgaactcggcgccgccgaggaccagttgccgccg cttccggtgcagtacgccgactacgcccactggcagcgcaccgccgcggccaccggcctg gacgagcacctcgcctactggaagcggcacctggccgacaccgcacccctggacctgccc accgaccggccccggccgccggtgcgcaccagctccggcgcgaccacccgcctcctggtg cccgcccggaccgcgcggcggctcgaccggctcgcccggcggcacgggaccaccctgttc accacgctcgtcgccgccgcccaggcctacctcgcccggctgtccggcgccgaggacatc accgtcggcaccgtcagctccggccgtgaccggcccgagacgcagggcctcgtcgggttc ttcgtcaacaccctggtgctgcgctcccgggccgaggccgagcagcccttcaccgggttc ctcaccgccgtacgacagaccgtcctcgacgccttcgcccaccaggacgtgccgttcgaa cgggtcgtggacgaggtcgacccggtccgcgacaccagccgcaccccgctcttccaggtc atggtcgtcctgcagaacaccccggccgccgcgctcgacctgcccggcctggacgtcacc gacgtcgaacccgagtcggaacaggccccgttcgacctcaccctggagttcgccgagacc ggcgacggagccctgcacggcctgctcacctacaacaccgacctgttcgacgcggccacc gccgagcggatggccggccagctcggcaccctgctgcacgccgtcgccgaggacccggac cgcccgctcggcgccctgccgctgacctccgacgacgagctgaagaccgtgctggagcag ggccggcccaccttccgcccggtgcccgaggccaccctgcccgccctgttcgaacggcag gcggcccgtaccccggacgcggtggcgctcgtggacggcgaccgggaacggacgtacgcc gacgtggaccgggccgccaaccggctcgcccaccggctcctgcgcgacggcgtcggaccg gagcgggtggtggccctggcgctgccccgctcggcggcggccgtggtggcccagctcgcg gtcgccaaggccggcggcgccttcctgcccgtggaccccgactacccgccccagcgccgg gagttcatgatccgcgacgcgggcgcccacctggtcctcgccgacccggccgaggtgtgg gccgccgacggaccggacacggcccccacggacgccgaccgccccaccgcgctcaccccc gcccaccccgcctacgtcatctacacctccggctccaccggcacccccaagggcgtggtc gtcacccaccggggcctcgcctccttcgccgcggcagccgccgaacagtacgcggccggc cccggcgaccgggtcctgcagttcgcctcgcccagcttcgacgcctccgtgctggagctg tgcgtctccctgctcggcggggccgcgctggtcaccggcgaggaggggccgctggtcggc gagcggctggcggaggtgctcgccgagcggcggatcagccacaccctgatcccgccggcg gcgctggccaccgtcccgcccgggaccgccgccgccctgccccacctgcgcaccctcatc gtgggcgccgaggcatgtccggccgacctggtcgacacctgggcccccggccgccggatg atcaactcctacgggcccaccgaggccaccgtggtcgccacctggaccggcccgctgacc cccggcaccggcaccccgcccatcggccgccccgcggccggcacccgcgtccgggtgctc gacgccgccctgcgccccgtaccgcccggcgtgaccggcgagctgtacctcgcgggcccc gggctcgcccgcggctacctgggccggcccggactcaccgcccagcggttcgtcgccgac ccgttcggcgcgcccggggagcggatgtaccgcaccggggacctggtccgctggaccgcc gacggccggctcgtcttcgccggccgcgccgacgaccaggtcaagctgcgcggcttccgc atcgaacccggcgagatcgagagcgcgctgcgccgcagccccctggtccgggacgccgtc gtggccgtacgcgccgaggacacccccggcgcaccggcccggctggtcgcctacgtcgtc ccggcacaggcgtccggcaccgcgctgcccgtcgccgagctgcggctgcacctggccggg ctgctgcccccgcacatggtgccggcggtgttcgtcccgctcgaccggctgccgctcacc ccgaacggcaagaccgaccggcgggcgctgcccgcgcccgggcccgtacccgccggggac ggcccgcggaccgcgccgcgcaccgacaccgaacgccggatcgcccgcatctgggccgac gtcctgggcatcgaggaggtcggcgccgaggacaacttcttcgcgctcggcggcgactcc gtcctcagcatgcaggtcgtctcccggctgcgccgcgacgggctgcacgtcgccacccgg gacctgttcacccaccagaccgtcgccgaactcgccaccgtggtccgcaccgcgccccgg cggaccggggacggcccggtgaccggcgaggtgcccctcaccccgatccaggactggttc ctcaccaccccgcgcgccgcccaccaccacttcaaccagtcggtgctgctggaactcgcc gaaacccccgacccgcgggcgctgcgcaccgcgctcgacgcgctgctggaccaccacgac gcgctgcgcatgcggttcacccgggacgcggacggctggcaccagttcaacccgccgccc gccaccgggtacgacctcctcgtccggcacgacctgaccggcctgtccgccgaggaggcc gacacggccatggcgaaggccgccgacgagctgcacgcgggcttcgacctggcccgcggc ccgcagctgcgggcggcgctgttcaccggggactccgaccggcccgcgtacctcctcctc gtcgcccaccacctggtggtggacgccgtctcctggcgcatcctgcgcgacgacctggag accgcctaccggcaggcccgccagggcgacccggtcgccctgggggagcgcggcaccagc ttccgggactggtcccgcgggctcgccgggtacgtcgccgagggcggcctcgatcatgaa ctgccgtactgggagcaggcggtgcgcacccaggaggccccggccccggcacccggcacg ggaccggccgccacggtgagcgtcgaactcggcgaggaggacaccacggccctgctgcgc gccgcacccaccgcctaccgcacccgcgtcaacgacgtgctgctggccgccctcgcgctg gcgctggcccgctggaccggacgcgaccgggtccgtctggacctggagggccacggccgc gaggacctgctcgacggcgtcgacctctcccgcaccgtcggctggttcaccaccgtgtac ccggtcgccctccaggtgcccgaccccggcgacctcggcccggagcgggactggcggtcc ctggtcaagtccgtgcggcgccagctgcgcgccgtacccggcaacggcctgggcttcggc gcgctgcgcaccttcggcccgcccgaggtccgcgcccgcctcggcggcagcgcgcacagc gaggtggtcttcaactacctcggccagtgggacgcccgccccgagaccgcgacgggcggc ctggtccgcgccgaacacggctccttcgggcaggaccacgacccgcgggaccccggctcg cacctgctggaggtggtgggcgcggtgcagcacggccggctcgccttcacctggcaccac cggcccggcgtccacgacacggcgaccgtgcgccgggtggccgaggagttcgccgcggcc ctgcgccacctggcccggcacgcccggggaggccggtga

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