Streptomyces sp. PBH53: QR97_09205
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Entry
QR97_09205 CDS
T10303
Name
(GenBank) transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
stpb Streptomyces sp. PBH53
Pathway
stpb00290
Valine, leucine and isoleucine biosynthesis
stpb00620
Pyruvate metabolism
stpb01100
Metabolic pathways
stpb01110
Biosynthesis of secondary metabolites
stpb01210
2-Oxocarboxylic acid metabolism
stpb01230
Biosynthesis of amino acids
Module
stpb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stpb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
QR97_09205
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
QR97_09205
Enzymes [BR:
stpb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
QR97_09205
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
HNHc_6
Dyp_perox_C
Motif
Other DBs
NCBI-ProteinID:
AKN69988
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Position
2083499..2085112
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AA seq
537 aa
AA seq
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MTETATSELLDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFGVGFIEGGWPGAN
PRDTEFFARAQEEIDFKHAQLVAFGATRRAGAKAAEDPQVKALLESGAPVITLVAKSHDR
HVELALRTTLDENLEMVRDTVSYLRDQGRRVFVDCEHFFDGYRANPEYAKAVVRTAAEAG
ADVVILCDTNGGMLPAQVHAVVSTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQ
CTANGYGERVGNANLFPVVAALELKYGKKVLPEGKLRETTRISHAIAEVVNLTPSTHQPY
VGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNTMRMLVSDMAGRASVELKGKELGIDL
GGDRELVGRVVERVKERELKGYTYEAADASFELLLRAEAEGRPLKYFDVESWRAIVEDRP
DGTHANEATVKLWAKSERIVATAEGNGPVNALDRALRVALEKIYPQLAELELVDYKVRIL
EGKHGTSSTTRVLISTSDGSGEWSTVGVAENVIAASWQALEDAYTYGLLRAGVAPAR
NT seq
1614 nt
NT seq
+upstream
nt +downstream
nt
atgaccgagacggcaaccagcgagctgctcgacgactcgttccacgtcttcgacaccacg
ctgcgcgacggcgcgcagcgcgagggcatcaacctcaccgtcgcggacaagctcgccatc
gcccggcacctggacgacttcggcgtcggcttcatcgagggcggctggcccggcgcgaac
ccccgcgacaccgagttcttcgcccgcgcgcaggaagagatcgacttcaagcacgcccag
ctggtcgccttcggcgccacccgccgcgccggcgcgaaagccgccgaggacccgcaggtc
aaggcgctgctggagtccggcgccccggtcatcaccctggtcgccaagtcgcacgaccgg
cacgtggagctggcgctgcgcaccaccctggacgagaacctggagatggtccgcgacacc
gtgtcgtacctgagggaccagggccgccgggtcttcgtggactgcgagcacttcttcgac
ggctaccgcgccaaccccgagtacgccaaggccgtcgtccggacggccgccgaggccggc
gccgacgtcgtcatcctctgcgacaccaacggcggcatgctccccgcccaggtccacgcg
gtcgtctccaccgtgctcgccgacaccggcgcccggctcggcatccacgcccaggacgac
accggctgcgcggtcgccaacaccctggccgccgtcgacgcgggcgccacccatgtgcag
tgcacggccaacggctacggcgagcgcgtcggcaacgccaacctgttcccggtggtggcg
gcgctggagctgaagtacggcaagaaggtgctgcccgagggcaagctgcgtgagacgacc
cgcatctcccacgccatcgccgaggtcgtcaacctgacgccgtcgacccatcagccgtac
gtgggcgtctccgccttcgcgcacaaggccggcctgcacgcctccgccatcaaggtcgac
ccggacctctaccagcacatcgaccccgagctggtcggcaacaccatgcgcatgctggtc
tccgacatggcgggccgcgcctcggtcgagctgaagggcaaggaactcggcatcgacctg
ggcggcgaccgggagctggtcggccgggtggtcgagcgggtcaaggaacgcgagctgaag
ggctacacgtacgaggccgccgacgcctccttcgagctgctgctgcgcgccgaggccgag
ggccggccgctgaagtacttcgacgtcgagtcctggcgggccatcgtggaggaccggccc
gacggcacccacgccaacgaggccacggtcaaactgtgggccaagagcgagcggatcgtc
gccaccgccgagggcaacggcccggtcaacgccctggaccgcgccctgcgcgtggcgctg
gagaagatctacccgcagctcgccgagctggagctggtcgactacaaggtccgcatcctg
gagggcaagcacggcacctcctccaccacccgggtactgatctccacctcggacggctcc
ggcgagtggtccacggtcggggtcgccgagaacgtcatcgccgcctcctggcaggccctg
gaggacgcgtacacgtacggcctgctccgggcgggcgtggcaccggcccggtag
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