Streptomyces sp. PBH53: QR97_26240
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Entry
QR97_26240 CDS
T10303
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stpb Streptomyces sp. PBH53
Pathway
stpb00300
Lysine biosynthesis
stpb00550
Peptidoglycan biosynthesis
stpb01100
Metabolic pathways
stpb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stpb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QR97_26240
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QR97_26240
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QR97_26240
Enzymes [BR:
stpb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QR97_26240
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
DHHA1
Motif
Other DBs
NCBI-ProteinID:
AKN72792
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Position
6077913..6079319
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AA seq
468 aa
AA seq
DB search
MIALSLAEIAAVVGGQTHDIPDPSVQVTGPVVRDSREVVPGSLFAAFVGERVDGHDYAPQ
VVAAGAVAVLASRPVGVPAIVVEDVQTALGALARHVVRRLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHIRYLTGLTPPKI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPEDGAALLNADDPLVRAMASRTKAKVVLF
GESAEADVRAENVRLTDSGQPAFRLHTPSGAADVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGKGRRTWA
VLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGIEASWLQLGAYNEGSWGEESVHVS
DAQAAIDLLRSELRPGDVVLVKASRSVGLESVAQALVESGAEGEVAAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagcagtcgtcggcgggcagacgcacgacata
ccggatccgtccgtccaggtcacgggaccggtcgtccgggactcccgcgaggtggtgccc
ggcagcctgttcgccgccttcgtcggcgagcgcgtggacggccacgactacgcaccgcag
gtcgtcgcggccggcgcggtcgccgtgctggcgtcccggccggtcggcgtccccgcgatc
gtcgtggaggacgtccagacggccctcggcgcgctcgcccggcacgtcgtacgcaggctc
ggcgcgaccctcgtcgccctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcgcaggtgctccagcgcaaggcgccgaccgtgttcacgcccggctcgctcaacaacgag
atcgggctgccgctgaccgccctgtccgccaccgaggagaccaggttcctcgtgctggag
atgggcgcccgcggcatcgggcacatccgctacctcaccggcctcaccccgccgaagatc
ggcctggtgctcaacgtcggcaccgcccacatcggcgagttcggcggccgcgagcagatc
gcccaggccaagggggagctggtcgaggcgctgcccgaggacggggcggccctgctcaac
gccgacgacccgctggtccgcgccatggcctcccgtaccaaggcgaaggtggtccttttc
ggagagtcggccgaagcggacgtacgcgccgagaacgtacgactcacggacagcggacag
cccgccttcaggcttcacacaccctccggtgcagccgatgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcgggctccctctcccgctggcgcatggag
gtcaccgagcgcccggacggcgtgaccatcgtcaacgacgcctacaacgccaaccccgag
tccatgcgggccgccctcagggcgctcgcggccatgggcaaggggcgccgcacgtgggcg
gtgctcggcaagatggccgagctgggggacgaggcgctcgccgagcacgacgccgtcgga
cggcttgccgtccggctcaacgtcagcaagctcgtcgccgtcggggggattgaagcctcc
tggctgcaattgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcgatcgacctgttgcgcagcgagttgcgcccgggggacgtcgtgctc
gtgaaggcgtcccggtcggtggggctggagagcgtcgcccaggcgctcgtcgagtccggt
gccgagggtgaggtcgccgcccgatga
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