Spirochaeta thermophila DSM 6578: Spith_1289
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Entry
Spith_1289 CDS
T02016
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
stq
Spirochaeta thermophila DSM 6578
Pathway
stq00230
Purine metabolism
stq01100
Metabolic pathways
stq01110
Biosynthesis of secondary metabolites
Module
stq_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
stq00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Spith_1289
Enzymes [BR:
stq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Spith_1289
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
AEJ61554
UniProt:
G0GFE0
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All DBs
Position
1442515..1446294
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AA seq
1259 aa
AA seq
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MPQNRVERVFVEKRPEYDVRARHLFEDLVTTLHIRSLTGLRVIHRYDVEGVSPETFERAL
TGIFAEPPVDLVYREELPVTGGWTLPVELLPGQYDQRADSAVQCLRLLEPEATPTVRYAT
VYVFEGDLTQAEKERIRSYLINPTDSREARLEKPSHLFEPVPDPPAHIPTIEGFISANEE
DLLHLREVMGLAMDLADLLHCQRFFKETAERNPTETEIRLLDTYWSDHCRHTTFLTEIAH
LEIPQGPYAPLYQASYRTYHALRSEVYGSSLPPETLMDMATIGMKYLRKTGALADLDESP
EVNACSIRIKVSTDGGEEDWLLMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRAYVY
QAMRVTGSGDPHTPIEETLPGKLPQIKITREAARGYSSYGNQVGLATGQVVELYHPGYVA
KRMEIGAVLGAVKAEHVRREEPVPGDVVILVGGRTGRDGIGGATGSSKAHDEKAIEKAGT
EVQKGNPPVERHLQRLFRRPEALRLIKRCNDMGAGGVSVSIGEIAPSVDIFLDRVPKKYA
GLTATELALSESQERMAVVTSREDAEAFIRYADEENLEATVVAEVTDSGRLRMFWKGLTA
VDLPRSFLATNGARRNTMVELPDPRPESSPLTFTCTEGEEGSILEAWKLRMGRLQSASQK
GLQILFDSSIGAGTVLSPYGGAHEDTPVDAMVSLIPVPGRDVRTASIMAFGFNPEIGSWS
PYHGAFYAVVESVCKVAATGGYWRNVRLSFQEYFPRPGSDPTRWGLPAAALLGALHAQMS
LGIPSIGGKDSMSGTYKDLDVPPTLVSFAVTTAPVDRVISPELKREGSKIYLIHTPTGDY
DLPDITALMENLEFLAQRIGEGVVISATALRADGIAGGLTRMTVGNRLGCVFVSEPRRED
LFCPRYGSFLVEVPVDVPHAPFERHPHASCIAVTGGDAVVIGREWISLEELLAVWTRPLE
DVFPSHEREKGRSFPFHTVEKETTRRRASHPKVARPRVCIPVFPGTNCEYDSAEAFRRAG
AEVDVLVFRNLTPTHIHESLEALARSIRNAQILMIPGGFSAGDEPEGSGKYIATVFRNAV
VRHALEDLIHHRDGLVLGICNGFQALIKLGLVPYGEIRDLEEDSSILTYNTSGHHVARYV
RTRLVSRLSPWFLKEEPGAVHVLPVSHTEGRFVAREEEARRLLDQGQVATQYVDPEGNPT
MDPRYNPNGSVLAVEGLTSPDGRILGKMAHSERIRPGVGKNIPGHKEERIFESGVAYFL
NT seq
3780 nt
NT seq
+upstream
nt +downstream
nt
atgccgcagaatcgagtggagcgcgtcttcgtcgaaaagagaccggagtacgatgtgagg
gcccgtcacctcttcgaggacctggtcaccaccctccacattcgatccctcacagggctc
agggtgatccatcgatacgacgtagagggagtctcgcccgagaccttcgagcgggcgctc
accggtatcttcgccgagcctccggtggatctcgtctaccgtgaggaactccccgtcacg
ggaggatggacgctcccggtggaactccttccgggacagtacgatcaacgggccgattcc
gcggtgcaatgtctcagactcctcgagccggaggcaacaccgacggtgaggtacgccacg
gtctacgtcttcgaaggggatctcacacaggcagaaaaggaaaggatccgctcatacctc
atcaaccccaccgattcccgggaggcgcggctggagaagccctcccacctcttcgagccc
gttccggatccaccggcacacatcccgacgatagaggggttcatctcggcgaacgaggaa
gacctcctccacctcagggaagtgatgggtcttgccatggatctcgccgatctcctccac
tgtcagcgcttcttcaaggagaccgccgagcggaaccccaccgagaccgagatccggctc
ctcgacacctactggtccgaccactgtcgtcacaccacgtttctcacggagatcgcccat
ctcgagatacctcaggggccctatgcccccctctatcaggcgagttacaggacctaccat
gccctcaggagcgaggtctacgggagctccctccctcccgagaccctcatggatatggca
accatagggatgaagtatctgaggaagacaggtgccctcgccgatctggacgaatcgccc
gaggtgaacgcatgcagcatcaggataaaggtgtccacggatgggggtgaggaggactgg
ctcctcatgttcaagaacgagacccacaaccaccccaccgagatagaaccgttcggaggg
gccgccacctgcctcggcggtgcgataagggacccgctctcgggccgcgcctatgtatac
caggccatgcgggtcacggggagcggggatccccatacaccgatcgaggagaccctcccg
ggaaagctgcctcagatcaagatcaccagggaagcggcgaggggctacagttcctacggg
aaccaggtggggctcgccacgggtcaggtggtcgaactctaccatcccgggtatgtggcg
aaacgcatggagatcggcgcggtgctgggagcggtgaaggcggaacatgtgcggcgtgag
gagcccgttccgggagacgtggtgatcctcgtgggaggaaggacagggcgcgatgggata
gggggtgcgaccggttcttccaaggcccacgatgagaaggccatagagaaggcgggtacc
gaggtccagaaggggaatccgcctgtggagcgtcacctccagcgtcttttccgtcggccc
gaggcgctgcggctcatcaagcgatgcaatgacatgggagcaggaggcgtgagcgtttcc
atcggggagatcgccccgagcgtggacatcttcctcgacagggtgcccaagaaatacgca
gggctcaccgccacggagctggccttgagcgagtcccaagagcggatggcggtggtcacc
tcccgggaggacgcagaggccttcatccgttatgccgacgaggagaacctggaggcgacg
gtggtggcggaggtcaccgattcggggcggctccgcatgttctggaaggggctcaccgcc
gtggaccttccccgctcctttctcgccaccaacggtgcccgccgcaacaccatggtggag
ctccccgatccacgacccgagtcctctcccctcacgttcacctgtaccgaaggagaggag
ggttccatcctcgaggcgtggaagctccgcatgggacgcctccagagcgcttcccagaag
gggctccagatcctcttcgacagctcgatcggcgccggcaccgtgctctcgccgtacggg
ggggcgcacgaagatacgcccgtggacgccatggtgagcctcatcccggtgccgggacgg
gacgtgcgcaccgcgagcatcatggccttcgggttcaaccccgagatcggatcctggagc
ccctaccacggcgccttctatgccgtggtggagtcggtctgcaaggtggcggccacgggc
ggctactggcggaacgtgcggctctccttccaggagtacttccccaggccgggaagcgat
ccgacccgatggggactgccggcggcagccctcctcggcgctctccatgcacagatgagc
ctggggatcccctccattggggggaaagatagcatgtccggcacctacaaggacctggac
gtaccccccacactcgtctcctttgcggtgaccacggccccggtggaccgcgtgatctcc
cccgagctcaaacgggaggggagcaagatctacctcatccacacccccacgggcgactac
gaccttcccgacatcacggcactgatggaaaacctggagttcctcgcacagcggataggg
gaaggggtggtcatctcggccactgcgctccgtgccgacgggatcgcgggggggctcacc
cgcatgacagtgggcaacaggttgggatgcgtattcgtctccgagcctcgacgggaggac
ctcttctgcccgcgctatggaagtttcctcgttgaagtaccggtcgacgtgccccacgcg
cccttcgagcggcatccccatgcctcatgcatcgcggtcacgggcggggatgccgtagtg
ataggccgggaatggatctccctcgaggagctcctcgccgtgtggacgaggcccctggag
gatgtcttcccttctcacgagagggaaaagggccgaagcttccccttccacaccgtggag
aaggaaaccacccggaggcgggcctcccacccgaaggtcgcccgtccgagggtgtgcata
ccggtattccccgggaccaactgcgagtacgattcggccgaggccttcaggcgcgcgggc
gccgaggtggacgtgctcgtcttcaggaatctgacgcccacccacatccacgaatcgctc
gaggccctcgcccggagcatcaggaacgcccagatcctcatgatccctggcggcttcagt
gcaggggacgaaccggaaggctccgggaagtacatcgccacggtcttcagaaacgccgtg
gtgcgccacgccctcgaggatctcatccatcaccgggacggcctcgtcctgggtatctgc
aacgggttccaggccctcatcaagctgggactggtcccctacggtgagatccgcgacctt
gaggaggattcctccatcctcacctacaacacctccggccaccatgtagcccgatacgtc
cgcacgcgtctcgtctcccgcctctccccgtggttcctcaaggaggagccgggagccgtc
cacgtgctcccggtctcccataccgaaggaaggttcgtcgcgcgcgaagaggaggcacgc
cgtctcctcgatcaaggccaggtggcgacccagtacgtggatccggaggggaatcccacc
atggaccctcgatacaatcccaatggatccgtcctcgccgtggagggcctcacgagcccc
gacggtcgcatcctcggcaagatggcccactccgaacgaatacggcccggagtggggaag
aacatacccggccacaaggaagagcgcatcttcgagagcggggtggcctatttcctgtga
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