Streptomyces sp. CNQ-509: AA958_25770
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Entry
AA958_25770 CDS
T03968
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
strc
Streptomyces sp. CNQ-509
Pathway
strc00470
D-Amino acid metabolism
strc00550
Peptidoglycan biosynthesis
strc01100
Metabolic pathways
strc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strc00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
AA958_25770
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AA958_25770
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AA958_25770
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
strc01011
]
AA958_25770
Enzymes [BR:
strc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
AA958_25770
Peptidoglycan biosynthesis and degradation proteins [BR:
strc01011
]
Precursor biosynthesis
Amino acid ligase
AA958_25770
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AKH85062
UniProt:
A0A0F7NEE1
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All DBs
Position
5964593..5965762
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AA seq
389 aa
AA seq
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MSSEHSYESQGRKPRVAVVFGGRSSEHGISVVTAGAVMAAIDRDKYEVLPIGITADGRWA
LTADDPARMAIADRQVPRVEELVDDEAEDGAVVLSADPGSREVVYAEPGQVPKALGEVDV
VFPMLHGPYGEDGTLQGMLDLSGVPYVGSGVLASAVGMDKEYMKRVFVSYGLPVGPYVVI
RPREWDQGAPGQEGAAARKKIVDFAADHGWPVFVKPARAGSSIGITKVGELGALEDALAE
ARRHDPKIIVEAAVEGREIECGVLEFEDGPRASVPAEIPPTTSHDFYDFEAKYIDSAAGI
VPAPLTAEETAEVQRLAVAAFEACSCEGLVRADFFRTADGGFVINEINTMPGFTPISMYP
RMWQESGVSYPELVDRLIQAALRRSTGLR
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagcactcctacgaaagccagggccgcaagccgcgcgtcgccgtcgttttc
ggcggacgcagctccgagcacggcatctccgtcgtcaccgcgggcgccgtcatggccgcc
atcgaccgggacaagtacgaggtgctgcccatcggcatcaccgcggacggccgctgggcc
ctcaccgcggacgaccccgcgcggatggccatcgccgaccgccaggtgccgcgcgtggag
gaactggtcgacgacgaggccgaggacggcgccgtcgtgctctccgcggaccccggcagc
cgcgaggtcgtctacgccgagccggggcaggtgcccaaggcgctcggcgaggtcgacgtc
gtcttcccgatgctgcacggcccgtacggcgaggacggcacgctgcagggcatgctcgac
ctctccggtgtgccgtacgtgggctccggggtgctggcctccgcggtcggcatggacaag
gagtacatgaagcgggtcttcgtctcgtacgggctgccggtcggcccgtacgtcgtgatc
cggccgcgcgagtgggaccagggcgcccccgggcaggagggcgcggcggcccgcaagaag
atcgtggacttcgccgccgaccacgggtggccggtgttcgtgaagccggcgcgggcgggt
tcgtccatcggcatcacgaaggtcggcgaactcggcgcgctggaggacgcgctcgccgag
gcgcgccggcacgacccgaagatcatcgtggaggcggcggtcgaggggcgcgagatcgag
tgcggcgtgctggagttcgaggacgggccgcgggccagcgtgcccgccgagatcccgccg
accaccagccacgacttctacgacttcgaggccaagtacatcgactccgccgccgggatc
gtgccggcgccgctgaccgcggaggagaccgcggaggtgcagcggctggcggtcgccgcg
ttcgaggcgtgctcctgcgaggggctggtgcgggcggacttcttccgcaccgccgacggc
ggcttcgtgatcaacgagatcaacacgatgcccggcttcacccccatctcgatgtacccg
cggatgtggcaggagtccggcgtgagttacccggagctggtcgaccggctcatccaggcg
gcgctgcgccgctcgacggggctgcgctag
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