Streptomyces sp. CCM_MD2014: NI25_18785
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Entry
NI25_18785 CDS
T04862
Name
(GenBank) pyruvate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
strd
Streptomyces sp. CCM_MD2014
Pathway
strd00280
Valine, leucine and isoleucine degradation
strd00640
Propanoate metabolism
strd00785
Lipoic acid metabolism
strd01100
Metabolic pathways
strd01110
Biosynthesis of secondary metabolites
strd01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
strd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NI25_18785
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NI25_18785
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NI25_18785
Enzymes [BR:
strd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
NI25_18785
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
AIV35298
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Position
complement(4294002..4295165)
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AA seq
387 aa
AA seq
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MTVMEQRGAYRPTPPPAWQPRTDPAPLLPDAEPHRVLGTKAADRADTELLRTLYARLVRG
RRYNAQATALTKQGRLAVYPSSTGQEACEIAAALVLEERDWLFPSYRDTLAVVSRGVDPV
EALTLLRGDWHTGYDPYEHRVAPLSTPLATQLPHAVGLAHAARLKGDDVVALAMVGDGGT
SEGDFHEALNFAAVWQAPVVFLVQNNGFAISVPLDKQTAAPSLAHKAVGYGMPGRLVDGN
DAAAVHEVLSDAVRRARAGGGPTLVEAVTYRVDAHTNADDATRYRGDAEVETWRRHDPVE
LLERELTERGLLDEEAIRAAREDAETMAADLRARMNRDPELDPLDLFDHVYAEPTPQLRE
QRDQLRAELAAEAETGAATAAPEGGHR
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atgacggtcatggagcagcggggcgcgtaccggcccacaccgccgcccgcctggcagccc
cgtaccgaccccgcgccgctgctgccggacgccgagccccaccgcgtcctcggcacgaag
gccgcggaccgcgccgacaccgagctgctgcgcacgctgtacgcccggctggtgcgcggc
cgccgctacaacgcgcaggccacggcgttgaccaagcagggccggctggccgtctacccc
tccagcaccggccaggaggcgtgcgagatcgccgccgcgctggtcctcgaggagcgggac
tggctcttccccagctaccgcgacaccctcgcggtcgtctcgcgcggtgtcgaccccgtc
gaggcgctcaccctgctgcgcggcgactggcacaccggctacgacccctacgagcaccgg
gtcgccccgctgtccacgccgctggccacccagctgccgcacgccgtgggcctcgcccac
gccgcccgcctcaagggcgacgacgtggtcgcgctggccatggtcggcgacggcggcacc
agcgagggcgacttccacgaggcgctgaacttcgccgccgtctggcaggccccggtcgtc
ttcctggtgcagaacaacggcttcgcgatctccgtcccgctcgacaagcagaccgcggct
ccgtcgctggcccacaaggccgtcggctacgggatgcccggccgcctggtcgacggcaac
gacgccgccgcggtgcacgaggtcctgtccgacgccgtacgccgcgcgcgggcgggcggc
ggccccacgctggtggaggcggtgacgtaccgcgtcgacgcgcacaccaacgccgacgac
gccacgcgctaccggggcgacgccgaggtggagacctggcgccggcacgacccggtcgag
ctgctggagcgggagctgaccgagcgcggcctgctcgacgaggaagccatccgcgccgcc
cgcgaggacgccgagaccatggccgcggacctgcgcgcccggatgaaccgggacccggaa
ctggacccgctggacctgttcgaccacgtctacgccgagcccacgccgcagttgcgcgag
cagcgggaccaactgcgtgcggagctggcggcggaggcggagaccggggccgcgaccgcc
gcgcccgaagggggacaccgatga
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