Streptomyces sp. CCM_MD2014: NI25_20120
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Entry
NI25_20120 CDS
T04862
Name
(GenBank) phosphoribosylglycinamide synthetase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
strd
Streptomyces sp. CCM_MD2014
Pathway
strd00230
Purine metabolism
strd01100
Metabolic pathways
strd01110
Biosynthesis of secondary metabolites
Module
strd_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
strd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NI25_20120
Enzymes [BR:
strd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NI25_20120
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AIV35528
UniProt:
A0A0N6ZM45
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Position
4576601..4578859
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AA seq
752 aa
AA seq
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MSRTPLDTVEHAAATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCS
YKSSKVHLRQFGEKAPESDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAA
TGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGE
VVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNKVILYGARTGGDGIGGASILASET
FDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSG
GMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPGKVDRFLEICEKWDVIATVIGEVT
DGDRLEIYWHGGKIVDVDPRTVAHEGPVYERPYARPDWQDALQADDANKLPRPRTSDELK
DQVLKLVGSPNQASKQWITQQYDHFVQGNTVLAQPEDSGMIRVDEESGLGVAIATDGNGR
YAKLDPYTGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAVRGLADGC
RQLGTPVTGGNVSLYNQTGEAAIHPTPVVAVLGVIDDVARRTPVAFQEDGQLLYLLGDTR
EEFGGSAWSQVIHDHLGGLPPKVDLERERLLGEILISASRDGMIDSAHDLSDGGLVQAVV
ESALLGGKGARLVVPDGLDAFTFLFSESAGRAVVAVPRSEEVRFNDMCGARGLPVTRIGV
VDGDAVEVQGEFTLPLADLREAHEGTIPGLLA
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atgagccggacgcctctggacacggtcgagcacgcggccgcgacccccgacgtcgagctg
ccctgggccgagctgggcctgaagaaggacgagtacgagagggtcgtggagatcctcggc
cgccgccccaccggcgcggagctggccatgtactcggtgatgtggtccgagcactgctcg
tacaagagcagcaaggtgcacctgcgccagttcggcgagaaggcccccgagtccgacgcg
atgctcgtcggcatcggcgagaacgccggtgtcgtcgacgtcggccagggctacgcggtc
accttcaaggtcgagtcgcacaaccacccgtcgtacgtggagccctaccagggcgccgcg
accggcgtcggcggcatcgtgcgcgacatcatcgcgatgggcgcccgcccggtcgccgtc
gtggaccccctgcgcttcggcgcggccgaccaccccgacaccaagcgcgtcctcccgggc
gtcgtcgccggcatcggcggctacggcaactgcctgggcctgcccaacatcggcggcgag
gtcgtcttcgacgcctgctaccagggcaacccgctggtcaacgccggtgccatcggcgtc
atgcggcacgaggacatccacctcgccaaggcgtccggcgcgggcaacaaggtcatcctg
tacggggcccgcaccggcggtgacggcatcggcggcgcgtcgatcctggcatccgagacc
ttcgacgacgccaagccgtccaagcgccccgccgtccaggtcggcgaccccttccaggag
aagctcctcatcgagtgcaccctggaggccttcgccgagaagctggtcgtcggcatccag
gacctgggcgcggcgggcctgtcctgcgcgaccagcgagctggcgtcgaacggctccggc
ggcatgcgcgtcaccctggacgacgtgcccctgcgcgactcgactctgtctcccgaggaa
atcctcatgagcgagtcgcaggaacgcatgtgcgcggtggtcgagccgggcaaggtcgac
cgcttcctggagatctgcgagaagtgggacgtcatcgccaccgtcatcggtgaggtgacc
gacggcgaccgcctggagatctactggcacggcggcaagatcgtcgacgtcgacccgcgc
acggtcgcgcacgagggcccggtctacgagcgcccctacgcccgtcccgactggcaggac
gccctccaggccgacgacgcgaacaagctgccccggccgcggacgtccgacgagctgaag
gaccaggtcctcaagctggtcggctcgcccaaccaggcgtccaagcagtggatcacccag
cagtacgaccacttcgtgcagggcaacaccgtcctcgcccagcccgaggactcgggcatg
atccgcgtggacgaggagtccggcctcggcgtcgccatcgccaccgacggcaacggccgc
tacgccaagctcgacccgtacacgggcgcgcagctggcgctggcggaggcctaccgcaac
gtggccacgaccggcgcgaagcccctcgcggtctccgactgcctgaacttcggctcgccg
gaggacccggcggtcatgtggcagttcgcggaggccgtgcgcggcctggccgacggctgc
cggcagctcggcaccccggtgacgggcggcaacgtctcgctctacaaccagacgggcgag
gcggccatccacccgaccccggtggtcgcggtcctcggcgtcatcgacgacgtggcccgc
cgcacgccggtcgccttccaggaggacggccagctgctgtacctgctgggcgacacgcgt
gaggagttcggcggctcggcctggtcccaggtgatccacgaccacctcggcggcctgccc
ccgaaggtcgacctggagcgcgagcgcctgctgggcgagatcctgatctccgcctcccgc
gacggcatgatcgactccgcgcacgacctgtccgacggcggtctggtccaggcggtcgtc
gagtcggcgctgctcggcggcaagggcgcgcgtctggtcgtacccgacgggctcgacgcc
ttcaccttcctcttctcggagtcggcgggccgcgcggtcgtcgccgtcccgcgctcggag
gaggtccgcttcaacgacatgtgcggcgcccgcggcctgcccgtcacccgcatcggcgtg
gtcgacggcgacgcggtcgaggtccagggcgagttcaccctccccctggccgacctgcgc
gaggcccacgaggggacgatcccggggctgctggcgtaa
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