KEGG   Streptomyces sp. 769: GZL_02915
Entry
GZL_02915         CDS       T03587                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
stre  Streptomyces sp. 769
Pathway
stre00290  Valine, leucine and isoleucine biosynthesis
stre00620  Pyruvate metabolism
stre01100  Metabolic pathways
stre01110  Biosynthesis of secondary metabolites
stre01210  2-Oxocarboxylic acid metabolism
stre01230  Biosynthesis of amino acids
Module
stre_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:stre00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    GZL_02915
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    GZL_02915
Enzymes [BR:stre01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     GZL_02915
SSDB
Motif
Pfam: HMGL-like IPMS_D2
Other DBs
NCBI-ProteinID: AJC55502
UniProt: A0A0A8EJ96
LinkDB
Position
complement(3078409..3080106)
AA seq 565 aa
MEDSTVHARHTAPLLPHTGVQRPSRMPTGKYHPYRPLGLPDRTWPDRVARQAPLWCSVDL
RDGNQALIEPMDVERKRRMFDLLVSMGFKEIEVGYPTASGDDHAFVRHLIEDDAIPEDVV
IQVMSPIRQDFIERTVRSLRGARRACLQVFNPTSEAQRRLVLRADRQATLALALDGARQA
LRLQDSLPGTELYLQYAPESYTQTEPDYALEICNAVLDFWAPRADHTLRINLPATVEVFP
PQEFADRIEYVSRHLAHRDRTLLSVHPHNDRGSGVAAAEMAVLAGAQRVEGTLFGNGERT
GNVCLITLAMNLFSQGVDPMLDLGTIDRIRRIVEDCNQMPVPARHPWAGDFVYTSFAGTH
QDAISKGLLARQKAGDRGVWDVPYLPVDPRDIGRDYQALIRINTQSGKGGIAHLLRSEYG
LELPRRLQIDFAAVMQQRCERAGGEASAPQLWLAFEETYALPRAADAPSRPPVPPIAEPT
GAAADRWHAPAQDLLGALGATGQVRHLQVDRVSGRLNGIVAYLEVVVGDRAFWAVGRHPE
ESEAVRRAVRSAARRAALPRTPVAP
NT seq 1698 nt   +upstreamnt  +downstreamnt
atggaggacagcaccgtccacgcacggcacaccgcacccctcctgccgcacaccggcgtg
cagcgccccagccgcatgccgaccggcaagtaccacccctaccggcccctcggactcccc
gaccgcacatggccggaccgggtggcccggcaagctcccctgtggtgcagcgtcgacctg
cgcgacggcaaccaggcgctgatcgaaccgatggacgtcgagcgcaaacgccggatgttc
gacctcctggtgtccatgggcttcaaggagatcgaggtcggctacccgacggcctccggg
gacgaccacgccttcgtccgccacctcatcgaggacgacgccatccccgaggacgtcgtc
atccaggtgatgtcccccatccgccaggacttcatcgagcggacggtccgcagcctgcgc
ggcgcccggcgcgcctgcctacaggtcttcaaccccacctccgaggcgcagcggcggctg
gtgctgcgcgccgaccggcaggccaccctcgccctcgccctcgacggcgcccgccaggcc
ctgcgcctgcaggactccctccccggcaccgagctctacctccagtacgcccccgagtcc
tacacccagaccgagcccgactacgcgctggagatctgcaacgccgtactggacttctgg
gcaccccgcgccgaccacaccctgcgcatcaacctccccgccaccgtcgaggtcttcccg
ccccaggagttcgccgaccggatcgagtacgtcagccggcacctcgcccaccgcgaccgc
accctgctctccgtgcacccgcacaacgaccgcggcagcggcgtcgcggccgccgagatg
gccgtgctggccggcgcgcagcgcgtcgagggcaccctcttcggcaacggggaacgcacc
ggcaacgtctgcctgatcaccctcgccatgaacctcttctcgcagggcgtcgacccgatg
ctggacctcggcaccatcgaccgcatccggcgcatcgtcgaggactgcaaccagatgccg
gtaccggcccgacacccctgggcgggcgacttcgtctacacctcgttcgccggcacccac
caggacgccatcagcaagggcctgctcgcccggcagaaggccggcgaccgcggcgtgtgg
gacgtgccctacctccccgtcgacccgcgcgacatcggacgcgactaccaggccctgatc
cggatcaacacccagtccggcaagggcggcatcgcccacctcctgcgcagtgaatacggc
ctcgaactgccccggcgcctgcagatcgacttcgccgcggtgatgcagcagcgctgcgaa
cgcgccgggggcgaggcgtccgccccgcagctgtggctggccttcgaggagacctacgcc
ctgccgcgcgccgcggacgccccctcgcgcccgccggtccccccgatcgcggaaccgacc
ggcgccgccgccgaccgctggcacgcccccgcacaggacctgctcggcgcgctgggcgcg
accggccaggtgcgccacctccaggtcgaccgggtctccggccgcctcaacggcatcgtc
gcctacctggaggtggtggtgggcgaccgcgccttctgggccgtcggccggcaccccgag
gagagcgaggcggtgcgccgcgcggtgcgctccgcggcccggcgcgccgccctgccgcgc
accccggtggcgccgtga

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