Streptomyces sp. 769: GZL_03206
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Entry
GZL_03206 CDS
T03587
Name
(GenBank) putative alpha-isopropylmalate/homocitrate synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
stre
Streptomyces sp. 769
Pathway
stre00290
Valine, leucine and isoleucine biosynthesis
stre00620
Pyruvate metabolism
stre01100
Metabolic pathways
stre01110
Biosynthesis of secondary metabolites
stre01210
2-Oxocarboxylic acid metabolism
stre01230
Biosynthesis of amino acids
Module
stre_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
GZL_03206
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
GZL_03206
Enzymes [BR:
stre01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
GZL_03206
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
AJC55792
UniProt:
A0A0A8EK11
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All DBs
Position
complement(3426860..3428470)
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AA seq
536 aa
AA seq
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MTDVPEAAVPDAFHVFDTTLRDGAQREGINLTVADKLTIARHLDDYGVGFIEGGWPGANP
RDTEFFQRARAEIDFQHAQLVAFGATRKAGVRVEDDPQVAALLESGAPVITLVAKSHVRH
VELALRTTPEENLAMVRDTVAHLRAHGRRVFLDCEHFFDGYALDPTYAKEVVRTASDAGA
DVVVLCDTNGGMLPAQVTAVVRTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQC
TANGYGERVGNSNLFPVVAALELKYGRQVLPAGKLAETTRISHAVAEVVNLTPSTHQPYV
GVSAFAHKAGLHASAIKVDPDLYQHMDPALVGNTMRMLVSDMAGRASIELKGKELGIDLG
GDRELVGRVVERVKERELAGYTYEAADASFELLLRAEVDGKPLRYFTVESWRAIVEDRPD
GTHANEATVKLWAKGERIVATAEGNGPVNALDRALRVALERIYPQLASMELVDYKVRILE
GALGTGSITRVLVSTSDGRGEWSTVGVAENVIAASWQALDDAYAYGLLRAGVTPQA
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgacggacgttcccgaagccgccgttcccgacgccttccacgtattcgacaccacgctg
cgcgacggcgcacagcgcgagggcatcaacctgaccgtcgccgacaagctgaccatcgcc
cggcacctggacgactacggcgtcggcttcatcgagggcggctggcccggcgccaaccca
cgggacaccgagttcttccagcgcgcccgcgcggaaatcgacttccagcacgcccaactg
gtcgccttcggcgccacccgcaaggctggcgtccgcgtcgaggacgacccccaggtcgcc
gcgctcctggagtccggcgccccggtcatcacgctggtcgccaagtcccacgtccgccac
gtcgaactggccctgcgcaccacgcccgaggagaacctcgcgatggtccgggacaccgtc
gcccacctgcgcgcccacggccgccgcgtcttcctcgactgcgagcacttcttcgacggc
tacgcactggacccgacctacgccaaggaggtcgtgcgcaccgccagtgacgccggcgcc
gacgtcgtggtgctctgcgacaccaacggcgggatgctgccggcacaggtgaccgcggtg
gtccgcaccgtcctcgccgacaccggcgcccggctcggcatccacgcccaggacgacacc
ggctgcgcggtcgccaacaccctggccgccgtggacgccggcgccacccacgtccagtgc
accgccaacggctacggcgaacgggtcggcaactccaacctcttcccggtcgtcgccgcc
ctggaactcaagtacggccgacaggtcctgccggccggcaagctcgccgagaccacccgc
atctcgcacgccgtcgccgaggtcgtcaacctcaccccctccacccaccagccctacgtc
ggggtctccgcgttcgcccacaaggccgggctgcacgcctccgcgatcaaggtggacccg
gacctctaccagcacatggacccggcgctcgtcggcaacaccatgcggatgctggtctcc
gacatggccggccgggcctcgatcgagctcaagggcaaggaactcggcatcgacctgggc
ggcgaccgggaactggtcggacgggtcgtcgagcgggtcaaggaacgggagctggccggc
tacacctacgaggccgccgacgccagcttcgaactgctgctgcgcgcggaggtggacggc
aagccgctgcgctacttcaccgtcgagtcctggcgcgccatcgtcgaggaccgccccgac
ggcacccacgccaacgaggcgaccgtgaagctctgggccaagggcgagcggatcgtggcc
accgccgagggcaacggcccggtcaacgcgctggaccgcgcgctgcgggtggccctggag
cggatctacccccagctggcctcgatggagctcgtggactacaaggtccgcatcctggag
ggcgccctgggcaccggctcgatcacccgggtcctggtctccaccagcgacggccgcggc
gagtggtccacggtcggcgtcgccgagaacgtcatcgccgcctcctggcaggcactggac
gacgcctacgcctacggcctgctgcgcgcgggggtcacgccgcaggcgtga
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