Streptomyces sp. 769: GZL_05503
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Entry
GZL_05503 CDS
T03587
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
stre
Streptomyces sp. 769
Pathway
stre00860
Porphyrin metabolism
stre01100
Metabolic pathways
stre01110
Biosynthesis of secondary metabolites
stre01120
Microbial metabolism in diverse environments
stre01240
Biosynthesis of cofactors
Module
stre_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
stre_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
stre00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
GZL_05503
Enzymes [BR:
stre01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
GZL_05503
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GFIT
Motif
Pfam:
HEM4
Trans_reg_C
3HB_CusB
Gas_vesicle
Motif
Other DBs
NCBI-ProteinID:
AJC58078
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Position
5953567..5954757
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AA seq
396 aa
AA seq
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MHDQLEPAGQERPGEPERALRPLDGFTVGVTAARRAEELGALLERRGAHVVHAPALRIVP
LPDDAELLDVTRALTEDPPDVVVATTAIGFRGWIEAAEGWGLGEALLGRLTGAELLARGP
KVRGAIRAAGLTEKWSPASESMAEVLDRLLAQGVAGRRVAVQLHGEPLPGFVEALRAGGA
EVIGVPVYRWMPPVDLGPVDRLLDAVLARGLDAVTFTSAPAAASLLRRAAERGIQPELLA
ALRQDVLVACVGPVTALPLEALDVPTRQPERFRLGPLVQLLCRELPGRVPPLPVAGRRLE
IRGRAAVVDGGLRPVPPAGMALLRALARRPGWVVARGELLRALPGTGRDEHAVETAMARL
RTALGEPRLIQTVVKRGYRLALDAPADTEKYGDGTA
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
atgcacgatcagctggagcctgccgggcaggagcggcccggggagccggagcgggcgctg
cgcccgctggacggcttcaccgtcggggtgaccgcggcccgtcgggcggaggagctgggc
gcgttgctggagcgccggggcgcccacgtggtgcacgccccggcgctgcgcatcgtgccg
ctgccggacgacgccgaactgctcgacgtcacccgtgcgctgaccgaggacccgccggac
gtggtggtggccaccaccgccatcgggttccgcggctggatcgaggcggcggagggctgg
gggctgggcgaggcgctgctgggccggttgaccggcgcggagctgctggcccgcggcccg
aaggtgcgcggcgcgatccgggccgccgggctgaccgagaagtggtcgccggcctcggag
tcgatggccgaggtcctcgaccggctgctggcgcagggcgtcgccgggcggcgggtcgcc
gtccagctgcacggggagccgctgccggggttcgtcgaggcgctgcgggccggtggcgcg
gaggtgatcggggtgccggtgtaccggtggatgccgccggtcgacctcgggccggtggac
cggctgctggacgcggtgctggcgcgcggcctggacgcggtgaccttcaccagcgcgccg
gccgccgcgtcgctgctgcgccgggccgccgagcgcggcatccagccggagctgctggcc
gcgctccggcaggacgtgctggtggcgtgcgtgggtccggtgacggcgctgccgctggag
gcgctggacgtgcccacccggcagccggagcgcttccggctggggccgctggtgcagctg
ctgtgccgggaactcccgggccgggtaccgccgttgccggtcgccgggcggcggctggag
atccgcggccgggccgcggtggtggacggcgggctgcggccggtgccgccggccgggatg
gcgctgctgcgcgccctggcccgccgccccggctgggtggtggcccgcggcgaactgctg
cgggcgctgccgggcacgggccgggacgagcacgcggtggagaccgcgatggcgcggctg
cggacggcgctgggcgagccccggctgatccagacggtggtcaagcgcggctaccggctg
gcgctggacgccccggcggacaccgagaagtacggcgacggcacggcctag
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