Streptomyces sp. 769: GZL_05704
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Entry
GZL_05704 CDS
T03587
Name
(GenBank) methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
stre
Streptomyces sp. 769
Pathway
stre00280
Valine, leucine and isoleucine degradation
stre00410
beta-Alanine metabolism
stre00562
Inositol phosphate metabolism
stre00640
Propanoate metabolism
stre01100
Metabolic pathways
stre01120
Microbial metabolism in diverse environments
stre01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
stre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
GZL_05704
00562 Inositol phosphate metabolism
GZL_05704
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
GZL_05704
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
GZL_05704
Enzymes [BR:
stre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
GZL_05704
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
GZL_05704
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Motif
Pfam:
Aldedh
HBM
Motif
Other DBs
NCBI-ProteinID:
AJC58279
UniProt:
A0A0A8ER50
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Position
6163720..6165213
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AA seq
497 aa
AA seq
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MKTINHWIGGKPVEGVSGNFGPVYNPATGAQEKQVAFASVEEVDAAVRTAKEAFRSWGTS
SLAKRTSVLFKYRELVDAHRDELAQLITAEHGKVHSDALGEVARGLEIVELACGIPEKLK
GELSTQVSTRVDVASIRQSLGVVAGITPFNFPAMVPMWMFPIAIACGNTFVLKPSEKVPS
AAFKLAELAAEAGLPDGVLNIVNGDKVAVDALLEHPDVAAVSFVGSTPIARYIHTTGTAN
GKRVQALGGAKNHMLVLPDADLDLAADSAINAAYGSAGERCMAISVVVAVGDTADPLIGK
IKERADKLRIGPGDDPASEMGPLITKAHRDKVASYVTGAAAQGADVVIDGTGYTVEGYED
GHWIGVSLLDNVTPEMDAYRDEIFGPVLSVVRVETYEQAIELMNSSPWGNGTAIFTRDGG
AARRFQLEVEAGMVGVNVPIPVPVGYHSFGGWKDSLFGDHHIYGNDGVHFYTRGKVVTTR
WPDPSDGGINLGFPRNH
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgaagaccatcaaccactggatcggcgggaagcccgtcgagggcgtctcgggcaacttc
gggccggtctacaacccggccaccggcgcccaggagaagcaggtcgccttcgcctccgtc
gaggaggtggacgccgcggtccgcaccgccaaggaggcgttccgcagctggggcaccagc
tcgctggccaagcgcacctcggtgctgttcaagtaccgcgagctggtggacgcgcaccgc
gacgagctggcccagctgatcaccgcggagcacggcaaggtgcactccgacgcgctcggc
gaggtcgcccgcggcctggagatcgtcgagctggcctgcggcatcccggagaagctcaag
ggcgagctgtccacccaggtctcgacgcgggtggacgtggcctcgatccggcagtcgctg
ggcgtggtcgccggcatcacgccgttcaacttcccggccatggtgccgatgtggatgttc
ccgatcgccatcgcgtgcggcaacaccttcgtcctgaagccgagcgagaaggtgcccagc
gccgcgttcaagctcgccgagctggccgccgaggcgggcctgcccgacggcgtgctgaac
atcgtcaacggtgacaaggtggccgtcgacgccctcctggagcacccggacgtcgccgcc
gtctccttcgtgggctccacccccatcgcccgctacatccacaccaccggcaccgccaac
ggcaagcgcgtgcaggcgctgggcggcgccaagaaccacatgctggtcctcccggacgcc
gacctcgacctggccgccgactccgcgatcaacgccgcgtacggctcggccggcgagcgc
tgcatggcgatctccgtggtggtggccgtcggcgacaccgccgacccgctgatcggcaag
atcaaggagcgcgccgacaagctgcgcatcggccccggcgacgacccggcctccgagatg
ggcccgctgatcaccaaggcccaccgcgacaaggtcgcctcctatgtcaccggcgccgcc
gcccagggcgccgacgtcgtcatcgacggcaccggctacaccgtcgagggctacgaggac
ggccactggatcggcgtctcgctgctggacaacgtcacgccggagatggacgcctaccgc
gacgagatcttcggcccggtgctctcggtcgtccgcgtcgagacctacgagcaggccatc
gagctgatgaattcctcgccgtggggcaacggcaccgcgatcttcacccgggacggcggc
gcggcccgccgcttccagctggaggtcgaggccggcatggtcggcgtgaacgtgccgatc
ccggtcccggtgggctaccactccttcggcggctggaaggactcgctcttcggcgaccac
cacatctacggcaacgacggcgtgcacttctacacccgcggcaaggtcgtcaccacccgc
tggcccgacccgtccgacggcggcatcaacctgggcttcccgcgcaaccactga
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