Streptomyces sp. 4F: ASR50_17660
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Entry
ASR50_17660 CDS
T04265
Name
(GenBank) phosphoribosylglycinamide synthetase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
strf
Streptomyces sp. 4F
Pathway
strf00230
Purine metabolism
strf01100
Metabolic pathways
strf01110
Biosynthesis of secondary metabolites
Module
strf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
strf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ASR50_17660
Enzymes [BR:
strf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ASR50_17660
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ALV51055
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Position
3964338..3966596
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AA seq
752 aa
AA seq
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MSKTPLDTVEHAAATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCS
YKSSKVHLRQFGEKAPESDALLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAA
TGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGE
VVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNKVILYGARTGGDGIGGASILASET
FDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSG
GMSVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPDKVDRFLEICDKWDVIATVIGEVT
DGDRLEIFWHGEKIVDVDPRTVAHDGPVYERPYARPSWQDELQADDANKLPRPATSEELR
DQVLKLVGSPNQASKQWITQQYDHFVQGNTVLAQPEDSGMIRIDEASGLGVAIATDGSGR
YAKLDPYTGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAVRGLADGC
KQLGTPVTGGNVSLYNQTGEAAIHPTPVVAVLGVIDDVARRTPVAFQEEGQLLYLLGDTR
EEFGGSAWSQVIHDHLGGLPPKVDLERERLLGEILISASRDGMIDSAHDLSDGGLIQAVV
ESALLGGKGARLVVPDGLDAFTFLFSESAGRAVVAVPRSEEVRFNDMCGARGLPVTRIGV
VDGDTVEVQGEFSLPLADLREAHEGTIPALLA
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atgagcaagacgcccctggacacggtcgagcacgcggccgcgacccccgacgtcgagctg
ccctgggccgagctgggcctgaagaaggacgagtacgagcgggtcgtggagatcctcggc
cgccggcccaccggagccgagctcgccatgtactccgtcatgtggtccgagcactgctcg
tacaagtcctccaaggtgcacctgcgccagttcggcgagaaggcccccgagtccgacgcc
ctgctcgtcggcatcggcgagaacgcgggcgtcgtggacgtcggccagggctacgccgtc
accttcaaggtcgagtcgcacaaccacccgtcgtacgtcgagccctaccagggcgcggcc
accggcgtcggcggcatcgtccgcgacatcatcgcgatgggcgcccgcccggtcgcggtc
gtggacccgctgcgcttcggcgccgccgaccaccccgacaccaagcgcgtcctgccgggc
gtggtggcgggcatcggcggctacggaaactgcctgggcctgcccaacatcggcggcgag
gtcgtcttcgacgcctgctaccagggcaacccgctggtcaacgcgggcgccatcggcgtc
atgcggcacgaggacatccacctcgccaaggcgtccggcgcgggcaacaaggtcatcctc
tacggggcccggaccggcggcgacggcatcggcggcgcgtcgatcctcgcctcggagacc
ttcgacgacgccaagccgtcgaagcgccccgcggtgcaggtcggcgaccccttccaggag
aagctgctcatcgagtgcaccctggaggccttcgccgagaagctggtcgtcggcatccag
gacctcggcgcggccggtctgtcctgcgccacgtccgagctggcctccaacggctccggc
ggcatgagcgtcaccctcgacgacgtgccgctgcgcgactccacgctctcgcccgaggag
atcctcatgagcgagtcgcaggagcgcatgtgcgcggtcgtggagcccgacaaggtcgac
cggttcctcgagatctgcgacaagtgggacgtcatcgccaccgtcatcggcgaggtgacc
gacggcgaccggctggagatcttctggcacggcgagaagatcgtcgacgtcgacccgcgc
acggtcgcgcacgacggcccggtctacgagcgcccctacgcccgcccgtcctggcaggac
gagctccaggcggacgacgcgaacaagctgccccgcccggcgacttcggaggagctgagg
gaccaggtcctgaagctggtcggctccccgaaccaggcgtccaagcagtggatcacccag
cagtacgaccacttcgtgcagggcaacacggtcctcgcccagcccgaggactccggcatg
atccgcatcgacgaggcgtccggcctcggcgtcgcgatcgccaccgacggcagcggccgc
tacgccaagctcgacccgtacacgggcgcgcagctcgccctcgcggaggcgtaccgcaac
gtcgccacgaccggcgccaagccgctcgccgtctccgactgcctgaacttcggctcgccg
gaggacccggcggtcatgtggcagttcgccgaggccgtgcgcggtctggcggacggctgc
aagcagctcggcacgccggtgaccggcggcaacgtctcgctctacaaccagacgggcgag
gcggccatccacccgaccccggtggtcgccgtcctcggcgtcatcgacgacgtggcccgc
cgcaccccggtcgccttccaggaggagggccagctgctctacctcctcggcgacacccgc
gaggagttcggcggctcggcctggtcgcaggtgatccacgaccacctcggcggtctgccg
ccgaaggtcgacctggagcgcgagcggctgctcggcgagatcctgatctccgcctcccgc
gacggcatgatcgactccgcgcacgacctgtccgacggcggtctgatccaggccgtggtc
gagtcggcgctgctcggcggcaagggcgcgcgtctggtggtgcccgacgggctggacgcg
ttcaccttcctgttctccgagtcggccggccgcgcggtcgtcgccgtgccgcgctcggag
gaggtccgcttcaacgacatgtgcggtgcgcgcggcctgccggtcacccgcatcggcgtc
gtcgacggcgacacggtcgaggtccagggcgagttctccctccccctggccgacctgcgc
gaggcccacgaggggacgattccggcgctgctggcctga
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