Streptomyces sp. JH002: H7827_06115
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Entry
H7827_06115 CDS
T11115
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
strj Streptomyces sp. JH002
Pathway
strj00470
D-Amino acid metabolism
strj00550
Peptidoglycan biosynthesis
strj01100
Metabolic pathways
strj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strj00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
H7827_06115
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
H7827_06115
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
H7827_06115
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
strj01011
]
H7827_06115
Enzymes [BR:
strj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
H7827_06115
Peptidoglycan biosynthesis and degradation proteins [BR:
strj01011
]
Precursor biosynthesis
Amino acid ligase
H7827_06115
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Paralog
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ZK643_helical
Motif
Other DBs
NCBI-ProteinID:
XVJ75205
LinkDB
All DBs
Position
complement(1459890..1461032)
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AA seq
380 aa
AA seq
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MSSDSTPQSPKPRVAVVFGGRSSEHTISVLTAGAVLRAIDRDRYDVLPIGITTDGRWALT
ADDPERMALSGRELPTVAAIAEPGGGSVLLPVDPAGREVVYCEPGSVPKDLGDVDVVFPV
LHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGMDKEYMKRVFTSFGLPVGPYTVVRPRE
WAADPAAARKKIVDFAADHGWPVFVKPARAGSSMGITKVSGLAGLDEAIAEAQAHDPKII
VESLLSGREIECGVLEFEEGPRASVPAEIPPVSQHDFYDFEAKYLDSAEGIVPAPLTPEQ
TARVQELSVLAYEAVSCEGLVRADFFLTEDGEFVINEINTLPGFTPISMYPRMWQASGME
YPELIDRLIQAALRRSTGLR
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgactccacaccccagagccccaagccccgcgtcgccgtcgtcttcggcggc
cgcagctccgagcacaccatctcggtcctgaccgcgggcgccgtgctccgcgcgatcgac
cgtgaccgctacgacgtgctgcccatcggcatcaccaccgacggccgctgggcgctgacc
gccgacgaccccgagcggatggccctcagcggccgtgaactgccgaccgtggccgccatc
gccgaacccggtggcggctcggtgctgctgccggtcgaccccgcgggccgcgaggtcgtc
tactgcgaaccgggctcggtgcccaaggacctcggcgacgtggacgtcgtcttcccggtg
ctgcacggcccgtacggcgaggacggcaccctccaggggctgctggagctgtccggcgtg
ccctacgtcggcgccggtgtgctggcctcggcggtcggcatggacaaggagtacatgaag
cgcgtcttcacctccttcgggctgccggtcggcccgtacaccgtggtccgcccgcgcgag
tgggccgccgacccggccgccgcccgcaagaagatcgtggacttcgccgccgaccacggc
tggccggtcttcgtcaagcccgcgcgggccggctcctccatgggcatcaccaaggtgagc
ggcctcgccggtctcgacgaggccatcgccgaggcgcaggcccacgacccgaagatcatc
gtggagtcgctgctcagcggccgggagatcgagtgcggcgtcctggagttcgaggagggc
ccgcgcgcctcggtgcccgccgagatcccgccggtctcccagcacgacttctacgacttc
gaggccaagtacctggactcggccgagggcatcgtgcccgcgccgctgacacccgagcag
accgcccgggtgcaggagctgtccgtgctcgcctacgaggcggtctcctgcgagggcctg
gtcagggcggacttcttcctcaccgaggacggcgagttcgtcatcaacgagatcaacacc
ctgcccgggttcacgccgatctcgatgtaccccaggatgtggcaggcctccgggatggag
taccccgaactgatcgaccggctcatccaggcggcgctgcgccgctccacggggctgcgc
tag
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