Streptomyces sp. JH002: H7827_07615
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Entry
H7827_07615 CDS
T11115
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
strj Streptomyces sp. JH002
Pathway
strj00270
Cysteine and methionine metabolism
strj00480
Glutathione metabolism
strj01100
Metabolic pathways
strj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
strj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
H7827_07615 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
H7827_07615 (egtA)
Enzymes [BR:
strj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
H7827_07615 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
XVJ75485
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Position
complement(1781413..1782774)
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AA seq
453 aa
AA seq
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MTTAPAAVPLREADAEARIGGACFTTGPPGRVGVELEWLVHDRIEPRRVVPARRVDAALA
ALEQPGSTALPGGSRLTREPGGQVELSTPPAASLIEAVRATATDLTALRSALAGEGLTTG
GLGLEPFRDPPRVLHDPRYGAMESYFDRVGPWGRLMMRATASVQINLDAGDESTGPAGYR
YRWRLAHRLGPVLLAAFANSPLWRGRRTGWVSTRQAVWARMDPTRTRPPDNHPTDADPRA
VWTRYALDAQLMCVRRTPPAGWDAPGGVTFRSWLRGALGEHRPRADDLDYHLSTLFPPVR
PRGWLELRMVDAQSGDRWVVPLVLAAVLMDDPVAAEAAYAATEPLTGGRPHPPAAVWLRA
AQRGPADPELGRAARACFAAADRALARDPHAAGLRRVLADFADRYTRRGRCPADDHPDPD
RTAAGPDRRVHRHHATHQADRPADPPIEGRFRP
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccgcacccgccgccgtccccctgcgggaggccgacgccgaggcccgcatcggc
ggcgcctgcttcaccaccggcccgcccggacgcgtcggcgtcgaactggagtggctcgtc
cacgaccgcatcgagccgcgccgcgtcgtccccgcccgccgcgtcgacgccgcgctcgcc
gcgctggagcagcccgggtccaccgcgctgcccggcggcagccggctcacccgcgagccc
ggcggccaggtcgaactgtccaccccgcccgccgcctccctcatcgaggcggtgcgcgcc
accgccaccgatctgaccgcgctgcgctccgccctggccggcgagggcctgaccaccggc
ggcctgggcctggagcccttccgcgacccgccccgggtgctgcacgacccccgctacggc
gccatggagtcctacttcgaccgggtcggcccgtggggccggctgatgatgcgggccacc
gcctccgtccagatcaacctcgacgccggggacgagtccaccggcccggccggctaccgc
taccgctggcggctggcccaccggctgggcccggtgctgctcgccgcgttcgccaactcc
ccgctgtggcgcggccgccgcaccggctgggtgtcgacccggcaggcggtgtgggcccgg
atggaccccaccaggacccgcccgccggacaaccaccccaccgacgccgacccccgcgcc
gtgtggacccgctacgcgctggacgcgcagctgatgtgcgtacgccgcaccccgcccgcc
ggctgggacgcgccgggcggcgtgacgttccgctcctggctgcgcggcgcgctcggcgag
caccggccgcgcgcggacgacctcgactaccacctcagcaccctgttcccgccggtccgc
ccgcgcggctggctggaactgcgcatggtggacgcgcagagcggcgaccgctgggtggtc
ccgctcgtcctggccgccgtgctcatggacgaccccgtcgccgccgaggccgcgtacgcc
gccaccgagccgctgaccggcggccgtccgcacccgccggccgccgtatggctgcgcgcc
gcccagcgcggccccgccgacccggaactcggccgcgccgcccgcgcctgcttcgccgcc
gccgaccgggccctggcccgcgatccgcacgccgccggcctgcgccgcgtgctcgccgac
ttcgccgaccgctacacgcggcgcggccggtgccccgccgacgaccatcccgaccccgac
cggacggccgccggacccgaccgccgcgtccaccggcaccacgccacccaccaggccgac
cgcccggccgatccgcccatcgaggggcggttccggccatga
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