KEGG   Streptomyces sp. JH002: H7827_26750
Entry
H7827_26750       CDS       T11115                                 
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
strj  Streptomyces sp. JH002
Pathway
strj00860  Porphyrin metabolism
strj01100  Metabolic pathways
strj01110  Biosynthesis of secondary metabolites
strj01120  Microbial metabolism in diverse environments
strj01240  Biosynthesis of cofactors
Module
strj_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:strj00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    H7827_26750 (cobA)
Enzymes [BR:strj01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     H7827_26750 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     H7827_26750 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     H7827_26750 (cobA)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7
Other DBs
NCBI-ProteinID: XVJ78904
LinkDB
Position
5838348..5839586
AA seq 412 aa
MPQPHPDHPAYPVGLRLTGRLVLVLGGGTVAQRRLPALLAAGADIRLIAPAVTPSVQAMA
EAGELRWERRGYRPGDLADAWYALVATDDPEVNAAASAEAERARVWCVRSDDAGAATAWT
PAIGRSEGVTVAVLTGRDPRRSAAVRDAVVEGLREGTLAAPRHRNRTPGVALVGGGPGDP
DLITVRGRRLLAEADVVVADRLGPRDLLDELPAHVEVIDAAKIPYGRAMAQEAINGTLIE
HARAGKSVVRLKGGDPYVFGRGMEEATALAEAGIPVTVVPGVTSAISVPGAAGIPVTHRG
VAHEFTVVSGHLAPDHPKSLVDWAGLARLRGTLVLLMAVERMPAIAATLIGHGRDPRTPV
AVIQDGTTTAQRRVDATLETAADRIAATGVRPPAVIVVGDVVTVADHPEETL
NT seq 1239 nt   +upstreamnt  +downstreamnt
atgccacagccacaccccgaccaccccgcgtaccccgtcggactgcggctgaccggtcgc
ctggtcctggtgctcggcggcggcaccgtcgcccagcgccgactgcccgccctgctggcc
gcgggagccgacatccggctgatcgcccccgccgtcaccccctccgtccaggccatggcc
gaggccggcgaactgcgctgggagcggcgcggataccggcccggtgacctggccgacgcc
tggtacgcgctggtcgccaccgacgaccccgaggtgaacgccgccgcctccgccgaggcc
gagcgcgcccgggtgtggtgcgtccgcagcgacgacgccggcgccgccaccgcctggacc
ccggccatcggccgcagcgagggcgtcaccgtcgccgtgctcaccggccgtgacccgcgc
cgttccgccgccgtacgggacgccgtcgtcgaagggctgcgcgagggcaccctggccgcg
cccaggcaccggaaccgcacgcccggggtggcactggtcggcggtggcccaggtgacccc
gacctgatcaccgtgcgcggccgccgcctgctggccgaggccgacgtggtggtcgccgac
cggctcgggccgcgtgacctgctggacgaactgcccgcccacgtcgaggtcatcgacgct
gccaagatcccctacggccgggccatggcccaggaggccatcaacgggacgctcatcgag
cacgccagggccgggaagtccgtggtgcggctcaagggcggagacccgtacgtcttcggc
cggggcatggaggaggccacggcactggcggaggccggcatcccggtcaccgtggtcccc
ggggtcaccagcgccatcagcgtgcccggcgcggccggcatcccggtcacccaccgcggt
gtcgcacacgagttcacggtggtcagcggccacctggcaccggaccaccccaagtcgctg
gtggactgggcgggcctcgcccggctgcgcggcaccctcgtgctgctgatggcggtcgaa
cggatgcccgcgatcgccgccaccctgatcgggcacggccgggacccgcgtaccccggtg
gcggtgatccaggacggcaccaccaccgcccagcggcgcgtcgacgccaccctggagacg
gccgccgaccgcatcgccgccaccggcgtccggccgcccgccgtgatcgtcgtcggcgat
gtggtgaccgtcgcggaccacccggaggagaccctgtga

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