Streptomyces sp. N50: R2B38_20310
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Entry
R2B38_20310 CDS
T11501
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
strk Streptomyces sp. N50
Pathway
strk00280
Valine, leucine and isoleucine degradation
strk00640
Propanoate metabolism
strk00785
Lipoic acid metabolism
strk01100
Metabolic pathways
strk01110
Biosynthesis of secondary metabolites
strk01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
strk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
R2B38_20310 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
R2B38_20310 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2B38_20310 (pdhA)
Enzymes [BR:
strk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
R2B38_20310 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
XFP_N
Motif
Other DBs
NCBI-ProteinID:
WOX11018
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Position
4574484..4575617
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AA seq
377 aa
AA seq
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MTVMEQRGAYRPTPPPAWQPRTDPAPLLPDAAPYRVLGTEAAAQADPALLRRLYAELVRG
RRYNAQATALTKQGRLAVYPSTTGQEACEVAAALVLQEQDWLFPSYRDTLAAVARGLDPV
QALTLLRGDWHTGYDPREHRIAPLSTPLATQLPHAVGLAHAARLKGDDVVALALVGDGGT
SEGDFHEALNFAAVWQAPVVFLVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVDGN
DAAAVHEVLADAVRHAREGGGPTLVEAITYRIEAHTNADDATRYRGDAEVEAWRAHDPIA
LLEHELTERGLIDEAGIKAARDAAETMAAELRAHMNQDPVLDPMDLFADVYAEPTPQLRE
QREQLAAELAAEREGTH
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgacggtcatggagcagcggggcgcgtaccggcccacaccgccgcccgcctggcagccg
cgcacggaccccgcgccgctgctgcccgacgccgcgccgtaccgcgtgctcggcaccgag
gcggccgcgcaggccgaccccgcgctgctgcgccggctctacgccgagctggtgcgcggc
cgccggtacaacgcgcaggccaccgccctcaccaagcagggccggctcgccgtgtacccc
tccaccaccggccaggaggcctgcgaggtcgccgccgcgctggtcctccaggagcaggac
tggctcttccccagctaccgcgacacgctcgccgccgtcgcccgcggcctcgaccccgtg
caggccctcaccctgctgcgcggcgactggcacaccggctacgacccgcgcgagcaccgc
atcgcccccctgagcaccccgctcgccacccagctcccgcacgccgtcggcctcgcccac
gcggcccgcctcaagggcgacgacgtggtggcgctcgccctggtcggcgacggcggcacc
agcgagggcgacttccacgaggcgctgaacttcgccgccgtctggcaggccccggtcgtc
ttcctggtccagaacaacggcttcgcgatctccgtccccctcgccaagcagaccgcggcc
ccctccctggcccacaaggccgtcggctacggcatgcccggccgcctggtcgacggcaac
gacgcggccgccgtgcacgaggtcctcgccgacgccgtacggcacgcgcgcgagggcggc
ggtcccacgctcgtcgaggccatcacgtaccgcatcgaggcccacaccaacgccgacgac
gcgacccggtaccgcggcgacgccgaggtcgaggcctggcgtgcgcacgacccgatcgcc
ctcctggagcacgaactcaccgagcgcgggctcatcgacgaggccggcatcaaggccgcg
cgcgacgccgccgagaccatggcggccgagctgcgcgcgcacatgaaccaggacccggtg
ctcgaccccatggacctgttcgccgacgtgtacgccgagcccaccccccaactccgcgag
cagcgcgaacagttggcggcggagctggcggccgagcgcgaggggacgcactga
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