Streptomyces sp. N50: R2B38_38775
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Entry
R2B38_38775 CDS
T11501
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
strk Streptomyces sp. N50
Pathway
strk00270
Cysteine and methionine metabolism
strk00480
Glutathione metabolism
strk01100
Metabolic pathways
strk01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
strk00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
R2B38_38775 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
R2B38_38775 (egtA)
Enzymes [BR:
strk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
R2B38_38775 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
WOX14426
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Position
complement(8746625..8747935)
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AA seq
436 aa
AA seq
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MSDTASDCSDCTEPRTAVTEPEVEALVRGICFKTGPPRTLGVEVEWLVHELRLPQLPVTT
ERLEAAYAALKTVPLRSALTVEPGGQLELSSSPAASLMECIGSVSEDLDAVRAVLRRDGL
GLVGVGHDPWHPPRRFLHEPRYDAMERCLDRTGPAGRRMMCTSASVQVCLDAGYEEPGPL
GLGRRWWLAHQLGAVLVAAFANSPLVGRSPTGWRSTRQLIWMEIGPGRAGGPTLDALPRD
AWTDHVLDSPVMCIRQDSGPWEVPEELTFREWIRSGSPRPPTREDLDYHVSTLFPPVRPR
GHLELRMIDAQPGDDGWIVPLAVTTALFDDPEAAETAYRAVKPLAERTQGLPAPHNPLWI
DAARYGLSDPELHEVALVCFAAALEALPRLGATTGVTDAVRAYFDRYVVRGRCPADDLLD
RVRGTDSRPHGKDIRT
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgtccgatacggcaagtgactgtagcgactgtacggagccccgtaccgcggtcaccgaa
cccgaggtggaggccctggtcaggggcatctgcttcaagaccggtccgccccgcacgctc
ggggtcgaagtggaatggctcgtccacgagctgcgtctgccgcagctccccgtgacaact
gaacgactcgaagcggcgtacgccgcgttgaagaccgtgcctctgaggtcggcgctcacc
gtcgagcccggcggccagctggaactcagctcgtcgcccgccgcctccctgatggagtgc
atcggttccgtctccgaagacctggacgccgtccgcgcggtgctgcgccgcgacggcctg
gggctggtcggcgtcggtcacgatccctggcatccgccgcgccggttcctgcacgagccg
cgctacgacgccatggagcgctgcctcgaccgcaccggtcccgcgggccgccgcatgatg
tgcacctcggcgtccgtgcaggtgtgcctggacgccggttacgaggaacccggtccgctc
ggcctgggccggcgctggtggctggcgcaccaactcggcgcggtcctggtggccgcgttc
gccaactccccgctggtcggccgcagccctaccggctggcgctccacccggcagctgatc
tggatggagatcggccccggccgcgcgggcggtccgaccctggacgcgttgccgcgcgac
gcctggaccgaccacgtcctggactcgccggtgatgtgcatacggcaggacagcggcccg
tgggaggtcccggaggagctcacgttccgggagtggatcaggtcggggtcgcccagaccg
ccgacccgtgaggatctcgactaccacgtctcgacactgttcccgccggtcagaccgcgc
ggccatctggaactgcgcatgatcgacgcgcagcccggggacgacggctggatcgtgccg
ctggccgtgacgacggcgctgttcgacgaccccgaggccgccgagaccgcctaccgggcc
gtgaagccgctggccgaacggacccaggggctgcccgcgccgcacaatccgctgtggatc
gacgcggcccgctacgggctgtccgacccggagctgcacgaggtcgccctcgtgtgcttc
gcggcggccctggaggcgctgccccgcctcggcgcgaccaccggggtcacggacgccgtc
cgcgcgtacttcgaccgctatgtcgtccggggccgctgccccgccgacgacctgctcgac
cgcgtgcgcggcacggacagccgcccgcacgggaaggacatccgcacatga
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