Streptomyces sp. RLB1-33: HEP84_16400
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Entry
HEP84_16400 CDS
T10398
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
strl Streptomyces sp. RLB1-33
Pathway
strl00300
Lysine biosynthesis
strl00550
Peptidoglycan biosynthesis
strl01100
Metabolic pathways
strl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HEP84_16400 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HEP84_16400 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HEP84_16400 (murF)
Enzymes [BR:
strl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HEP84_16400 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
QIY70537
UniProt:
A0A6H1KTT3
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All DBs
Position
complement(3606236..3607666)
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AA seq
476 aa
AA seq
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MIALSLAEIAAVVGGQTYDIPDPAVQVTGPVVRDSREVEPGSLFVAFVGERVDGHDFAEA
VVAAGAVAVLASRPVGVPAIVVADVQAALGALARHVVERLGATLVALTGSAGKTSTKDLI
AQVLRSKAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHISYLADLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVESLPSAEAGGVAVLNADDPLVRAMASRTKARV
ILFGESGEADVRAENVRLTDAGQPAFRLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIALALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGKASQ
AEGGRTWAVLGQMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLERVAQALLDSGAEGEVAAR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagcagtcgtcggcgggcagacgtacgacata
ccggatccggcggtacaggtcaccggaccggtcgtcagagactcccgtgaagtggagcca
ggcagcctcttcgtcgccttcgtcggcgagcgcgtggacggccacgacttcgccgaggcc
gtcgtcgcggcgggcgcggtcgccgtactggcctcccggcccgtcggcgtgcccgcgatc
gtcgtcgcggacgtgcaggcggccctgggcgccctcgcgcgtcacgtcgtcgaacggctc
ggcgcgaccctcgtggccctcaccggctccgcgggcaagaccagcaccaaggacctgatc
gcccaggtcctgcggagcaaggcgccgaccgtcttcacgcccggctcgctcaacaacgag
atcggactgccgctgaccgcgctgagcgccaccgaggagaccaggttcctcgtcctggag
atgggcgcccgcggcatcggccacatcagctacctcgcggacctcacgccaccgaggatc
ggcctcgtcctgaacgtcgggaccgcccacatcggtgagttcggcggccgcgaacagatt
gcacaggcgaagggcgagctcgtcgagagccttccgtcggcggaagcgggcggcgtcgcc
gtcctcaacgccgacgaccccctcgtacgcgccatggcgtcccgcacgaaggcgcgcgtg
attctcttcggagagtccggcgaagcggacgtacgtgccgagaacgtccgtctcacggac
gccggacagcccgcattcaggcttcacacaccctccgggtgcagcgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcagacgagatcgccctcgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgccctgcgcgcgctcgcggcaatgggcaaagcctcacag
gcagaagggggtcggacgtgggcggtgctcggtcagatggccgagctcggggacgaggcg
ctcgccgagcacgacgcggtcgggcggctcgccgtccgactcaacgtcagcaagctcgtc
gcggtcgggggcagggaagcttcctggctccaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcacaggcggctgtcgacctgttgcgcagcgag
ttgcgcccgggggacgtcgtgctcgtgaaggcgtcccggtcggtcgggctcgaacgggtg
gcgcaggcgctgctcgacagcggtgccgagggtgaggtcgcggcccgatga
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