Streptomyces sp. RLB1-33: HEP84_35415
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Entry
HEP84_35415 CDS
T10398
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
strl Streptomyces sp. RLB1-33
Pathway
strl00290
Valine, leucine and isoleucine biosynthesis
strl00660
C5-Branched dibasic acid metabolism
strl01100
Metabolic pathways
strl01110
Biosynthesis of secondary metabolites
strl01210
2-Oxocarboxylic acid metabolism
strl01230
Biosynthesis of amino acids
Module
strl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
strl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HEP84_35415 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HEP84_35415 (leuC)
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NCBI-ProteinID:
QIY73652
UniProt:
A0A6H1LS33
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Position
7813427..7814851
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPDGVTA
KDLILAIIAKIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
EYLKGRAHAPEGEEWGAAVAYWKTLKSDEDAVFDAEVVIDGPSLAPFVTWGTNPGQGAPL
SASVPDPASYEDASERMAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAAAA
IVEGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPVPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgccaggcggggcgtcccgtgcgccgtctcgacctcaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagcccatcgcggacccagtctcccgg
gcccagctggagaccctgcgcaagaactgcgccgagttcggtgtacggctgcactcgctg
ggtgacgtcgagcagggcgtcgtccacgtggtgggaccgcagctgggtctgacccagccc
ggcaccaccgtggtctgtggcgactcccacacctccacgcacggcgccttcggcgcgctg
gcgttcggcatcggcacctcgcaggtcgagcatgtgctggccacccagacgctgccgctg
gcccgccccaagaccatggccatcacggtcgacggcgagctgcccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaagatcggtacgggtggcggccagggctacatc
ctggaataccgcggctccgccatcgagaagctctcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gagtacctcaagggccgtgcgcacgcccccgagggcgaggagtggggcgccgcggtcgcg
tactggaagaccctgaagtcggacgaggacgcggtcttcgacgccgaggtcgtcatcgac
ggcccgtcgctggcgccgttcgtcacctggggcaccaaccccggccagggagcgccgctt
tcggcgtccgtccccgacccggcttcgtacgaagacgcttcggagcgcatggccgccgaa
aaggccctggagtacatggggttgaccgccggacagccgctgcgcgacatcaaggtcgac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgcg
atcgtcgagggccgcaaagtcgccgacggcgtacggatgctggtggtccccggttccgcg
cgggtcggtctgcaggccgtctccgagggcctggacgtggtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctcgaaccgtaacttcgagggcaggcagggcaagggcggc
cgtacgcatctcgtatcgccgcaggtggccgccgcgaccgcggtgctgggccacctggcc
tccccggccgacctgtccgacgcccccgtgcccgctggagtctga
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