Streptomyces sp. MOE7: STRMOE7_27280
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Entry
STRMOE7_27280 CDS
T05374
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
stro
Streptomyces sp. MOE7
Pathway
stro00290
Valine, leucine and isoleucine biosynthesis
stro00660
C5-Branched dibasic acid metabolism
stro01100
Metabolic pathways
stro01110
Biosynthesis of secondary metabolites
stro01210
2-Oxocarboxylic acid metabolism
stro01230
Biosynthesis of amino acids
Module
stro_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
STRMOE7_27280
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
STRMOE7_27280
Enzymes [BR:
stro01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
STRMOE7_27280
4.2.1.35 (R)-2-methylmalate dehydratase
STRMOE7_27280
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ARH93372
UniProt:
A0A1W5XU04
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Position
6132295..6133734
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AA seq
479 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRQVRRTDLTIAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLAPFKTMAITVDGELPEGVTA
KDLILAIIAKIGTGGGQGYVLEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDRTTF
DYLQGRDHAPEGEDWDAAVEYWKTLRTDDDAVFDAEVHIDASALSPFVTWGTNPGQGAPL
SANVPDPASYEDASERFAAEKALEYMGLTAGQPLREINVDTVFVGSCTNGRIEDLRSAAS
ILQGRKVADGVRMLIVPGSVRVSLEAVAEGLDKVFTEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLATAGQSDVATPAGV
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgggacggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgcggaaggc
gagcccgacctcctcttcattgatctgcacctgctgcacgaggtcaccagcccgcaggcg
ttcgacggcctccgcaaggccggccgccaggtgcgccgcacggacctgaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcgcgc
acccagctggagacgctgcgcaagaactgcgccgagttcggggtccggctgcacccgctg
ggcgacgtcgagcagggtgtcgtccacgtcgtggggccgcagttggggctgacccagccc
ggcaccaccgtggtctgcggtgacagccacacctccacccacggagccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcacgtcctggccacccagacgctgccgctg
gcccccttcaagaccatggcgatcaccgtcgacggtgagctgccggagggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaagatcggcaccggcggcggccagggctacgtc
ctggaataccgcggcccggccatcgagaaactgtcgatggaagcccgaatgaccatctgc
aacatgtcgatcgaggcgggcgcccgggccggcatgatcgcccccgaccggaccaccttc
gactacctccagggccgcgaccacgcccccgagggcgaggactgggacgccgcggtcgag
tactggaagacgctgcgcaccgacgacgacgcggtcttcgacgccgaggtgcacatcgac
gcctccgcgctgtcgccgttcgtcacctggggcaccaaccccggccagggcgcaccgctt
tcggcgaacgtccccgacccggcttcgtacgaggacgcctcggagcgcttcgccgccgaa
aaggccctggaatacatggggttgacggcgggtcagccgctgcgcgagatcaacgtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgctccgcggcctcg
atcctgcagggccgcaaggtcgccgacggcgtacggatgctgatcgtccccggttcggtc
cgggtctccctggaggccgtcgccgagggtctggacaaggtcttcaccgaggcgggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggcgccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggccgtcagggcaagggcggt
cgtacgcacctggtctcgccgcaggtcgccgccgcaacggctgttctcggccatctggcc
tcaccggccgacctggccacggccggccagtccgacgtcgccacgcccgcgggagtctga
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