Streptomyces sp. 11-1-2: CGL27_14265
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Entry
CGL27_14265 CDS
T11393
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
strq Streptomyces sp. 11-1-2
Pathway
strq00300
Lysine biosynthesis
strq00550
Peptidoglycan biosynthesis
strq01100
Metabolic pathways
strq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CGL27_14265
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CGL27_14265
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CGL27_14265
Enzymes [BR:
strq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CGL27_14265
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
FimL_2nd
AIRS
Motif
Other DBs
NCBI-ProteinID:
ASQ94080
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Position
complement(3441282..3442712)
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AA seq
476 aa
AA seq
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MIALSLTEIAGLVGGQPHDIPDPDLKVTGPVVIDSREVRPGSLFAALPGERVDGHDFARR
AIEAGATAVLAARPVGTADAPVPAIVVPDVIAAMGALARAVVERLDATVVGLTGSAGKTS
TKDLIAQLLQRRGPTVWTPGSLNNEIGLPLTAMSADEATLHLVLEMGARGKGHIRYLTDL
TPPRIGLVLNVGTAHIGEFGGREQIAEAKGELVEALPPAEEGGVAVLNADDPLVRAMVSR
TKARTVLFGEAEDADVRAGNVRLADGGRPAFTLHTPTGCSEVTMRLYGEHHVSNALAAAA
VAHELGLSVDEIAVALSEAGQLSRWRMEVTERSDGVTVVNDAYNANPESMRAALRALAAM
GAATPGRRTWAVLGPMAELGEESLAEHDAVGRLAVRLNVSKLVAVGGQEAAWLDMGAKNE
GSWGEESVHVSDVRAAVDLLRSELRPGDVVLVKASRSVGLERVAQVLLEGEGEGVR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcactgtccctcaccgagatcgccggcctagtcggtggacagccgcacgacata
ccggacccggacctgaaggtcacgggccctgttgtgatcgactcccgtgaggtgcggccc
ggcagcctcttcgccgcgctccccggggagcgcgtggacggccacgacttcgcccgaagg
gcgatcgaggccggggccacggcggtcctggccgcccgccccgtcggcaccgcggacgcc
cccgtaccggcgatcgtcgtgcccgatgtcatcgccgccatgggagcgctcgcacgcgcc
gtcgtggagcgcctggacgccactgtggtcgggctcaccggctccgcgggcaagaccagc
accaaggacctcatcgcccagctgctccagcgccgcggccccaccgtatggacgccgggc
tcgctcaacaacgagatcggcctgccgctcaccgcgatgagcgccgacgaggccaccctg
cacctggtgttggagatgggtgcccgcggtaagggccacatccggtacctgacggacctc
accccgccccgtatcggactcgtgctcaacgtcggcaccgcccatatcggagagttcggc
ggccgggagcagatcgccgaggccaagggcgagctcgtggaggccctgccccccgccgag
gagggcggggtggcggtgctcaacgccgacgaccccctggtgcgcgccatggtgtcgcgc
accaaggcccgtaccgtcctgttcggcgaggccgaggacgccgatgtgcgtgccgggaat
gtccggctcgccgacggcggccgccccgccttcacgcttcacacccctaccgggtgcagc
gaagtgaccatgcgcctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgcc
gtcgcccacgagttgggcctgtccgtcgacgagatcgccgtggcgctctccgaggcgggg
cagctctcccgctggcggatggaggtcaccgagcgctcggacggcgtgacggtcgtcaac
gacgcctacaacgcgaaccccgagtccatgcgagcagcgctgcgcgcgctggccgccatg
ggcgctgccacaccggggcgtcgcacgtgggcggtgctcggcccgatggccgagctgggc
gaggagtcactggccgagcacgacgcggtcgggcggctggccgtccggctcaacgtcagc
aagctcgtggcggtcggcggccaggaggccgcctggctggacatgggcgccaagaacgag
ggttcgtggggtgaggagtcggtgcacgtgtccgacgtgcgggcagcggtcgatctgctg
cgcagcgagctgcgaccgggggacgtcgtgttggtgaaggcatccaggtcggtggggctg
gagcgggtcgcgcaggtgttgctcgagggcgagggtgagggcgtccgctga
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