Streptomyces sp. 11-1-2: CGL27_45085
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Entry
CGL27_45085 CDS
T11393
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
strq Streptomyces sp. 11-1-2
Pathway
strq00270
Cysteine and methionine metabolism
strq00480
Glutathione metabolism
strq01100
Metabolic pathways
strq01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
strq00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CGL27_45085 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
CGL27_45085 (egtA)
Enzymes [BR:
strq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
CGL27_45085 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
ASR00725
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Position
complement(10637615..10638838)
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AA seq
407 aa
AA seq
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MEARLHGICFKTGPPRRIGVELEWLLYDPHVPARPIEAARLEAAVTALRGLPLRSAITFE
PGGQVELSSLPADSLTECVESAAADLVLVRSLLTGLGLGLAGHGHDPWRPPRRFLTTPRY
ECMETYFDRRGPAGRSMMCSTASVQVCVDAGHEEPGPLGMARRWRLAHLLGAVLTAAFAN
SPLRQGRPTGYRSTRQAVWTAMEPGRTHAPPDGGDPRTAWAHYVLDAPVMAIRDEKGPWA
VPSGVTFRQWARTGLPRPPTLDDLDFHVSTLFPPVRPRGHLELRMIDAQSGEDGWIVPLA
VTVALFDDPQAAETVYRVVKPLAETAGARPAPGNRLWRAAARHGLAEPELRAAAVSCFAT
ALDALPRLGASPAITAAVAAFTDRYVARGRCPADDLLAPLTGKEGRP
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atggaggcccggctgcacggcatctgcttcaagacagggccgccgcgccgcatcggagtc
gagctcgaatggctcctgtacgacccgcacgtccccgcacgacccatcgaggcggcccgg
ctcgaagccgcggtcaccgccctgcgcggactgccgctgcggtccgccatcaccttcgaa
cccggcggccaggtggagctcagctcccttccggccgactccctcaccgagtgtgtggag
tccgccgccgccgatctggtcctcgtacgctcccttctcaccgggctcggcctcggcctg
gccggccatggccacgacccctggcgcccgccgagacggttcctcaccacaccccggtac
gaatgcatggagacctacttcgaccgccgggggccggccgggcgctccatgatgtgcagc
accgcctccgtgcaggtctgcgtggacgccggacacgaggagcccggaccgctcggcatg
gcacggcgctggcggctcgcccatctgctgggcgcggtgctgaccgccgcgttcgccaac
tcgccgctgcgccagggccgccccacgggctaccgctccacccggcaggcggtgtggacg
gcgatggagcccggccgcacccacgccccgcccgacggcggggatccccgcaccgcctgg
gcgcactatgtgctggacgcgcccgtgatggccatccgggacgagaaggggccctgggcg
gtgccgtccggggtgaccttccgccagtgggcccggacggggctgccccggccgcccacc
ctcgacgatctcgacttccacgtctccacgctctttccccctgtccgcccgcgcggccat
ctggaactgcgcatgatcgacgcgcagagcggtgaggacggctggatcgtccccctcgcc
gtcacggtcgccctcttcgacgatccgcaggctgctgaaacggtttaccgggtggtgaag
ccgctcgccgagacggcgggcgcacgccccgcacctggcaatcggctgtggcgggccgcc
gcgcgccacggtctggccgaacccgagctgcgcgccgccgccgtcagctgcttcgccacg
gcgctggacgcgctgccccgcctcggcgcctcccccgccatcaccgccgccgtcgccgcc
ttcaccgaccgctatgtggcccgcggccgatgtcccgccgacgatctgctcgctcctctc
accggtaaggagggacggccatga
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