Streptococcus salivarius NCTC 8618: SSAL8618_08025
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Entry
SSAL8618_08025 CDS
T03511
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
strs
Streptococcus salivarius NCTC 8618
Pathway
strs00300
Lysine biosynthesis
strs00550
Peptidoglycan biosynthesis
strs01100
Metabolic pathways
strs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SSAL8618_08025
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SSAL8618_08025
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SSAL8618_08025
Enzymes [BR:
strs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SSAL8618_08025
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
GT-B_Sucrose_synth
Motif
Other DBs
NCBI-ProteinID:
AIY21661
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All DBs
Position
complement(1758836..1760209)
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AA seq
457 aa
AA seq
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MKLTLHEIAKVVGAKNDVTAYEDVAINQIEFDSRKITAGDLFLPLKGARDGHDFIQTAFD
NGALATFTEKELPADQVHILVDDALEAFQKLAAYYLEKTEVDVIAVTGSNGKTTTKDMIH
DILATTYRTYKTQGNYNNEIGLPYTALHMPDDTEKIVLEMGQDHMGDIHLLSTLAKPKTA
VVTLIGEAHLEFFGSRDKIAQGKMQMQDGMPDGSLLLVPSDPIVDPFLPSNLEVVRFGDG
AELTVSELTEFKDHLTFSTNFLDGQVTLPVTGKYNATNAMVAAYVAKHLGVTEENILSAL
ANLQLTKNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPKNEGGKKIAVLADMKE
LGEQSVQLHTQMILSLTPDAIDTVIFYGEDIAELSQLASQMFPLGHVYYFKKTANEDQFD
AMVKQIKESLGEHDQILLKGSNSMNLAKVVEELQAKN
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaaactgacactccatgaaattgccaaggttgttggcgctaaaaatgatgtcacagcc
tatgaagatgttgccattaaccagattgagtttgatagccgtaagattacagcgggtgac
ctctttttaccactaaaaggtgcgcgtgatgggcatgattttatccaaacagcctttgac
aatggtgccctagcgacattcacagaaaaagaattaccagctgatcaagtccacatccta
gttgatgacgctcttgaagcctttcaaaaactagctgcctactatcttgaaaagactgag
gttgatgttattgctgtgactggttctaatggtaagacaacaaccaaggacatgattcat
gatatcttggcaacaacctatcgtacttacaaaacccaaggcaattacaacaatgagatt
ggtcttccttatacagccctccacatgcctgatgatactgagaaaatcgtccttgagatg
gggcaagaccacatgggagacattcacctcttgtcaaccctggctaagccaaaaacagcc
gttgttaccttaatcggagaggctcatttggaattcttcggtagccgtgacaagattgcc
caaggtaaaatgcaaatgcaagacggtatgcctgatggtagcctcttgcttgtgccaagt
gatcctatcgtagatcctttcttgccaagcaatcttgaagtggtacgctttggggatggt
gcggagcttacagtctctgagttgacagaattcaaggaccatctcaccttttcaacaaac
ttcctagacggacaagttaccttgccagtcactggaaaatacaatgccacaaatgccatg
gttgctgcctatgtggctaaacacttgggtgtaactgaggaaaatatcctctcagctctt
gccaacttgcagcttacaaaaaaccgtaccgaatggaaaaaagcagccaacggtgccgat
atcctttcagacgtttacaatgccaatccaacagccatgaagctcattttggagaccttc
tcagccattcctaagaatgaaggaggcaagaagatcgctgtcctagctgatatgaaagaa
ctcggtgaacagtctgttcaacttcacacacagatgattctcagcctgacaccagatgct
attgatacggtgattttctacggtgaagacattgcagaattgtcacaacttgctagtcaa
atgttcccacttggtcatgtttattatttcaagaaaacagctaacgaagaccaatttgac
gctatggtcaagcaaatcaaagaaagcctgggcgagcacgatcaaatcttgctcaaaggc
tctaactctatgaacctagccaaggttgtagaagaactccaagctaagaattaa
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