Salmo trutta (river trout): 115153437
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Entry
115153437 CDS
T08542
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit-like isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
stru
Salmo trutta (river trout)
Pathway
stru00270
Cysteine and methionine metabolism
stru00480
Glutathione metabolism
stru01100
Metabolic pathways
stru01240
Biosynthesis of cofactors
stru04216
Ferroptosis
Module
stru_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
stru00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
115153437
09106 Metabolism of other amino acids
00480 Glutathione metabolism
115153437
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
115153437
Enzymes [BR:
stru01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
115153437
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
115153437
NCBI-ProteinID:
XP_029554739
Ensembl:
ENSSTUG00000049933
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All DBs
Position
18:49171574..49199597
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AA seq
629 aa
AA seq
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MGLLSQGSPLNWEETKKYADHVRKHGIVQFLNIYNKVKERQKDVLLWGDEVEYMLIEMDE
KNEKVRLVLNGGEVLETLQDKGEKTNPKSHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNT
VEDNMGKRRREASSVLNKNETLATITSFPRLGCPGFTQPEYNPTPVEKGVSKSLFFPDEA
INRHPRFSTLTRNIRHRRGEKVVINVPIFKDKCTPSPFVEKFPEDDGEAARAALPDHIYM
DAMGFGMGNCCLQVTFQACSIEEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWG
VISASVDDRTGEERGLEPLKSNKFRILKSRYDSIDSYLSSCGDKYNDIDLTIDEEINKEL
LDAGIDKLLAQHIAHLFIRDPLSLFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNS
DIGWRVEFRPMEVQLTDFENSAYVVFIVLLTRVILSYKLDFLIPLSKVDENMKAAQERNA
VQEGMFYFRKDIYKGCNPVLDSSSAAQNGLDSEGDHYILMSIDTIINGKEGVFQGLIPIL
NCYLENMEVDVDTRCTILNYLKLIKRRASGELMTMAKWMREFVDKHTQYKQDSVITDKIN
YDLLRKCDSIAKGEERCPELIGDPVNRGK
NT seq
1890 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcacaagggtcaccgctcaactgggaagaaaccaaaaagtatgcagac
catgtcaggaagcatggaatcgttcagtttctcaacatctataacaaggtgaaagaacga
cagaaggatgtattgttatggggcgatgaggtggaatacatgttgattgaaatggatgag
aaaaatgaaaaggttcgtcttgttctcaatggtggggaggttttggaaacccttcaagac
aaaggtgaaaagacaaaccccaagagccatcctaccctttggaggccagagtatggcagc
tacatgatcgaagggactccagggcagccatacggtgggacgatgtcagagttcaacaca
gtggaggacaacatgggaaagaggaggcgagaggcctcatctgtgctgaataagaatgaa
acccttgccaccatcacatcattcccaaggttaggttgtccaggcttcacccagccagag
tacaacccaacacctgttgaaaaaggagtgtccaaatcactgtttttcccagatgaagcc
ataaacagacacccaagattcagcaccctgaccagaaacattcgtcacagaagaggagag
aaggtagtgatcaacgtacccatctttaaagacaagtgcactccatctccatttgtggag
aagtttccggaggatgatggggaggccgccagagcagctctccctgatcacatctacatg
gatgccatgggctttggaatgggcaactgctgtcttcaggtgacattccaagcttgcagc
attgaagaggcgaggtacctttatgaccaactagcaacattctgccccatagtgatggcc
ctcagtgctgcttcgccgttttacagaggctatgtgtcagacattgattgtcgctgggga
gttatttctgcctcggtggatgacaggaccggggaagagagagggctggagcctttgaaa
agcaacaaatttcgaatcttgaaatcaagatatgattcaatcgacagctacctctccagt
tgtggcgataagtacaatgacatagatctgacaatagacgaggagatcaacaaagagttg
ctggatgcagggatcgacaaactgctggcccaacacatagcccatcttttcatccgggat
ccgctgtcactctttgaagagaaaattcacctggatgatgaaaacgagtcggatcacttt
gagaatctgcagtcaaccaactggcagacaatgaggttcaaacctcctcctccaaactcg
gacatcggatggcgagttgagttccgccccatggaggtgcaacttaccgattttgaaaac
tctgcttacgttgttttcatcgtcctgctcaccagggttatcctgtcctataaactggac
tttctcatccccttgtcaaaggttgatgaaaacatgaaagcggcccaggaaagaaatgca
gtccaagagggcatgttttacttccggaaggacatctataaaggctgtaaccctgtcctc
gatagctcctcagcggcccagaacggcttggacagtgagggtgaccattacatactgatg
agcattgacacaatcatcaatggaaaggaaggtgtttttcaagggctgataccaatcctt
aactgctacctggaaaacatggaggtggacgtcgatacaagatgcaccatcctgaactac
ctgaagctcatcaagagacgcgcctcaggtgaactgatgaccatggcaaagtggatgagg
gagtttgtcgacaagcacactcaatacaagcaagacagtgtaataactgacaaaataaac
tatgacttactccgcaagtgtgacagtatcgcaaaaggagaggagcgatgcccagaactt
attggagacccagtcaatcggggcaaataa
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