Salmo trutta (river trout): 115156643 Help Entry 115156643         CDS       T08542                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism stru  Salmo trutta (river trout) Pathway stru04020   Calcium signaling pathway stru04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:stru00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     115156643 (ryr3)    04020 Calcium signaling pathway     115156643 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:stru04040]     115156643 (ryr3) Ion channels [BR:stru04040]  Voltage-gated cation channels   Ryanodine receptor    115156643 (ryr3) SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Motif Other DBs NCBI-GeneID:  115156643 NCBI-ProteinID:  XP_029560058 LinkDB All DBs Position 1:complement(7894546..8136810) Genome browser AA seq 4852 aa AA seqDB search MAEGGEGEDDIQFLRTDDEVVLQSVATIQKENRKFCLSVEGLGNRLCFLEPTSEAKYVPP DLCICCFILEQSLSVRALQEMLAHTVPNNEGKADHEQWAAQGGGHRTLLYGHAILLRHSF SGMYLTCLKTSRSLTDKLSFDVGLQEDSIGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSISSGSFQVDASFMQTLWNVQPTCSGSNVAVGFLCGGHVMHLCHGHDESLT IPGSEASEMEQRIVNYEMGKGASRARSLWRLEPLRIGWSGSHIRYGQAFRLRHLSTGHYL ALTEEHGLVLQEREKSDTKSTSFCFRATKEKIESGTKNRDIEGMGVAEIKYGDSACFVMH VATGLWLSYQAPDAKASRIGPLKRRACLHAEGHMDDGLTLQRCQHEEARAVRIIRNTTVL FSHFIKGLDSIGRDKNVEVSLPNFEEVLQTLDDLIEYFKQPDSELEHEEKQTLLRSLIKR QDLFKEEGMLALLVMCIDRLNLYNSAAHFGEHAGEEAGAAWKNILNLLYQLLASLIKGNR NNCTQFSRNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQKGHIKSIISLLYKHG RNHKILDVLCSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVAE GSAQYKKWYFELMIDQVDHYVTSEPSHLRVGWASTKGYAPYPGGGEGWGGNGVGDDLYSY SFDGLYLWSGRISRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTD GFFFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMRVEAVKEYKRDYG GVRDLLGTTQFLSQASFIPTPVDTSQIVLPPHLDNVRDRLAENIHELWGMNKIELGWCYG KVRDDNKRQHPCLVDFTKLPETERNYNLQMSSETLKTLLALGCHVTQTNVNAEEDLKKVK LPKDYVMSNGYKPTPLDLSEVKLTAGHEVLVDKLSENAHNVWAKERIKQGWTYGIQQDVK SRRNPRLVPYALLDERTKKSNRDSLREAIRTLVGYGYNIDPPDQEPCHIVEKQSIETIRF FRVEQTYAVKTGKWYFEFEALTGGDMRVGWARPGCRSDFDLGMDDQAYVFDGYKGRRMHM GARFFGQSWNEGDVVGCMINMEDKSMVFTLNGELLITNKGSELCFVDFETDDGFIPVCCL AQSEIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNIPKDHNH IEVTRIDGTVDNPPCLKVTHKTFGTQQSNSDMLYCRLSMPVELHAPHVSPDESQKLSQPP KEDDYGRITTYYHSVRVFAGQDPASVWVGWVTPDYHYHSKQFSLNKTRTVTVTLGDERGR VHESVRRSNCYMVCAGDVVGSSHSSSRSNIDLEIGCLVDLATGFLSFTANGKELATTYEV ESNTKLFPAVFVRPTSTNLFQFEFVKIKAAMPLSSAIFKSEQRNPVPQCPPRLDVQTIVA VLWSRMPNTFLTVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDILELSENEGLRKF HYHTLMLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLMSIHLET AKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVGLSTSLKPRLIFSPLSFITTKK QQHLHSPQIPLGILKEKAISMLTEAVQGGGSHIRDPVGGSVEYQFVPILKLIGTLLIMGV LTSEEVRLILLLIDPNVFGEPEEEEVEAASAGGGEKEEVSSNEEKAVEAGEEETKEVKPT VKGLLEKTLPESVKRQMCELLHYFCDCELKQRIEAIVSFSDSFVSKLQYNQKFRYNELML ALNMSAAVTAKKTKEFRSPPQEQINILLNFAAGEDCPCPEEIQEDLYKFHDELRLHCGIP VEEEEEEEDTSIKGRLLAMLYKIKGPPKKLEEETTEEEQAAPTNLKELISQTMASWAQEC SIQDPELVRVMFSLLRRQYDGIGALLRAMKKSYTISAVSVQDCVNLLASLGQIRSLLSVR MGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPKMV ASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAASSVMDNNSL ALALEEPDLEKVVTYLAGCGLQSCAMLLAKGYPDIGWNPIEGERYLSFLRFAVFSNGESV EENSNTVVKLLIRRPECFGPALRGEGGNGLLAAMLEAIKISEDPALDLPSTAEGEPSGSG EDEEEEVAHTGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTTDLVG IISIPLKMPIVNKDGSVTEPDMSASFCPDHKAPMVLFLDRVYGVEDQSFLLHLLEVGFLP DLRASASLDTDVLSTTETALAMNRYIGSALLPLLTRCADQFSGTEHYAALIDSTLHTIYR LSKGRSLTKAQRDSIEECLLAICKHLRPSMMQQLLRRLVFDVPLLAEYCKMPLRLLTEHY EQSWMYYCLPSGLGSSGMASEEELLLTKKLFWGIFDSLSTKKFDSDLFKTAMACLSAIAG ALPPDYMDASPGVTLEKQASVDAHGNFDPKPINTANMSLPEKLDYIANKFAEHSHVKWSS EKVTAGWKMGECVDDDAKTHPLLKPYKSLSEKERETYRWPVKESLKSMLAMGWNMERTKE GEAMLIRKQSKISESTQDNDNEFIPEPPLDLNNITLSRELQGMVEVVAENYHNIWAKKKK AELNSKGGGSHPLLVPYDTLTAKEKYRDREKVQDLFKFLQINGYTITRGLKDMEQDSSSM EKRFAYTFLKRLLKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLIDMYFK NHSMYFLSSPSKNLSSSGYASNKEKEMITSLFCKMAALVRHRISLFGSDSAIMVSCLHIL AHSLDTRTVMKSGSEMVKAGVRTLFENAAEDLEKTLEMLKLGKFSQSRSQMKGLSQNITY ATTALLPILTALFEHVTMHNFGVCLLVDDVQLSCYRIVTCLYSLGTGKHIFMERHLPALG ECLATLVGAMPVAFLEPDLNAHNPLSVFNTKTPRERAILSMPDSVEEMCSDMPRLDRLLK DINDISESGARYTEMPQVIEVILPMLCNYLSYWWERGTENSAPHTACCTTVCSHHLSIIL GNILKILNNNLGIDDAPWMKRIAVYSQPIICKAAADLLKSHFLPTLEKLRKKTVKVVAEE ELLKADIKGDTQEAELLVLDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKRPDAQSNELFT MVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGEHKTKMSKSGGDQDRKHKKRRGEL YSVQTSLIVAALKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKDHLRENLHLQDK SDDLAVQWQMNLYKDVVVVGSEEHADPEQTVDRIQSISAAVFHLEQVEQPLRMKKCVFQK LLSKQRKRAVVACFRMAPLYNLPRHRSINLFVLGYVRLWIETEEYSFEERLVQDLAKTPM KIVEEEEEEEVEIQPDPLHQLILHFSHNALTERSFLEEDPLYIAYADMMAKSCAEDEEEE EEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGIS ILNGGNVLVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTDEG SINSERGSKVLTNDDFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTLTVNIIISTVDYLL RLQESISDFYWYYSGKDIIDEAGQVNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLAHSR LWDAVVGFLHVFANMQMKLSQDSCQIELLKELMDLQQDMVVMMLSLLEGNVVNGTIGKQM VDTLVESSSNVEMILKFFDMFLKIKDLTTSDNFREYDPDNKGVISKKDFQKSMENQKQYT QSEIEFLLSCAEADENDMFNYEEFVERFHEPAKDIGFNIAVLLTNLSEHMPHDPRLATFL EPAESVLNYFEPYLGRIEIMGGGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNE GGESEKMEMFVNFCEDTIFEMQLASQISEPEVVERPEEEEEEVHNLLEELAEQEEERELE ASSAFTMVCVSAKKKISNFREMLTFKSLKKQYKKSKKLSMKEVILGFFSFFWTLFAGFFK GIYSLIFGFFHLIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVLETEKVEVSD SVSGGTDQAIKPSDKAEQDILMEMINPMPKKGEGLKHVDPGLGDVSENLTAETTATVEKK KAASEPTESEPEKADTEKKEKEDKVKVEQPKEEMAQDKPVLKSRNGQSKEAPTSFFASFL AGLEVYQAKMLNTLARNFYNMRFLALFVAFAINFILLFYRVTAAEDDEDDSWTSSDDEDE GGEEYFVLEESTGYMAPILCFLAVFHTALSILCLVGYYFLKVPLVVFKREKGIARLLEFE GLYITEQPADDDIMGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDLYGAERIAELLGLD KSALDFDPTQETVVEAASLVSWLSSIDTKYHIWKMGVVLTDNSFLYLIWYATMSILGHYN NFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNK SEDEDAPDMKCDDMMTCYLFHLYAGVRAGGGIGDELEDPAGDPYELWRILFDITFFFFVI VILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNL ANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDLLG NT seq 14559 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggagaagatgatatacagttcttgcgaactgatgatgaggtg gtgctgcagagtgttgccaccatccagaaggagaatcgcaagttttgtctgtccgtggag ggactcggaaatcgactatgcttcctagaacctacatctgaggctaagtatgttcctcct gacctttgtatctgttgtttcatcttggagcagtccctgtctgtccgggccctgcaggag atgttggctcatacagtgcctaacaacgaggggaaagcggaccatgaacagtgggcggcc caggggggtggacaccggaccctgctctatggtcacgccatcctcctacgccactccttc agcggaatgtacctgacctgcttgaagacatcaagatcgttgacagacaaactgtcattt gacgtgggattacaagaagattcaataggagaggcatgttggtggaccatccaccctgcg tccaagcagaggtcagagggagagaaggtccgtatcggagacgacctcatcctggtcagc gtgtccacagagaggtacctgcacctgtccatctctagtggtagtttccaggtggatgcc tcctttatgcagactctgtggaatgtccagcctacctgctcaggaagcaacgtggctgta ggattcctgtgtggtggtcacgtgatgcatctttgtcacgggcatgatgagagtctgacc atacctggatcagaggccagcgagatggagcagaggattgtgaactatgagatgggtaaa ggagcatccagggcccgctctctctggaggctggagcccctcaggatcggttggagcggt agccacattcgctatgggcaggcgttccgtctgcgtcacctgtccaccggtcactacctg gcgctgaccgaagaacatggtctggtcttacaggagagagagaagtctgataccaagtcc acctctttctgcttcagggctaccaaggaaaagatagagtcaggtacaaagaatcgagac atagaaggtatgggagtagcagagatcaagtatggggactccgcctgcttcgtgatgcac gtggctacaggcctgtggctgtcctaccaggcgcctgacgctaaagcctcccgcatagga cccctgaagagaagggcctgtctgcatgctgagggtcatatggacgacggtctgaccctt cagcgttgtcaacacgaggaggcacgggctgtacgcatcatcaggaacactactgtcctc ttcagccacttcatcaagggtcttgacagtataggaagggataagaatgtggaggtgtct ctgcctaactttgaagaggtgttgcagacgctggatgatctgattgagtatttcaaacag cctgactcagaactggaacatgaggagaaacaaactctgctgagatctctcatcaaacga caggacctcttcaaagaggagggcatgctggccctgttggtgatgtgcattgaccgtctc aacctgtacaacagcgctgctcactttggagagcatgctggggaagaggctggggcggca tggaagaacatcctcaacctactctaccaactactggcctctctgatcaaagggaaccgg aacaactgtacccagttctccaggaacctggactggctggtcagcaagctggagagactg gagtcctcatcaggtatcctggaggtgctccattgtatcctgatagagtctccagaggct ctgaacatcatccagaaaggacacatcaagtccatcatctccctgctctacaaacacgga cgcaaccacaagatcctggacgttctgtgctctctgtgtgtgtgtaacggggtggcagtg agagccaatcagaacctcatctgtgatcacctgcttccgaagagagacctgctcctccag acacgattggtcaatgacgttcagagtatgaggcctaacatcttcctaggagtggcagag ggttcagcccagtataagaagtggtactttgagttgatgatcgaccaggtggaccactat gtgaccagcgagccgtcccacctgcgtgtgggctgggcctccactaagggttatgccccc tacccggggggtggagagggatgggggggcaacggagtgggtgacgacctttactcatac agctttgacggactctacctgtggtcaggccgtatctcccgggcggtagcctcgatcaac cagcacttgttgaacagtgatgacgtggtgagctgttgtctggacctgggtgctccctcc atgtccttcaggatcaacgggcagccagtacagggcatgtttgaagacttcaacaccgac ggattcttcttcccagtagtcagcttctctgcgggggtcaaggtgcgtttcctgctgggt ggtcgtcatggagactttaagttcctgcccccagcgggttactccccgtgttacgaggcc cttctccccaaggagaagatgagggtggaggctgtaaaggagtacaagagagactatgga ggggtcagggacctactggggacaacacagttcctctcccaggcctcattcatccccaca cctgtagacaccagccagattgttctacctcctcacctggacaacgtgcgtgacagacta gcagagaacatccatgaactttggggcatgaacaagattgaactgggatggtgctatggc aaggttcgagatgacaacaagaggcagcacccttgcctggtggatttcaccaagctgcct gaaactgagaggaactataacctgcagatgtctagtgaaactctcaagaccctgttggca ttgggatgtcatgtgacacagaccaacgttaacgctgaggaagatctgaagaaagtcaaa ctgcccaaagactatgtgatgtctaacgggtataagccaacgccgctggatctttcggag gtgaaactgacagctggtcatgaggttctggtagataaactgtcagagaatgctcacaac gtttgggccaaggagaggatcaaacaaggatggacctacggcatacagcaagatgtgaag agcaggcgaaaccctcgtctggtgccgtacgctttactagacgagagaaccaagaagtct aacagagacagtctgagagaggccatcaggaccctggtgggatatggctacaacatcgac cccccagaccaggaaccctgtcatattgtggagaagcagagcattgagacgatcaggttc ttccgcgtagagcagacgtatgcagtgaagacagggaagtggtactttgagtttgaggcc ctgaccggaggggacatgagggttggctgggctagaccaggctgtaggtcagattttgac ctgggcatggacgaccaggcctacgtcttcgatggatacaagggtcgtcgaatgcacatg ggggcgcgtttcttcggtcagtcatggaacgagggagacgtggtgggctgcatgatcaac atggaggacaagtctatggtcttcaccctcaatggagagctactcatcactaacaaggga tccgagctctgcttcgttgacttcgagacagatgatggcttcatcccagtgtgttgtctg gcccagtctgagattggccgtatgaacctggggaaggacgccagcacctttaagtactac accatgtgtggcctgcaggagggcttcgaacccttcgctgtcaacatgaacagagaggtc accatgtggttcagcaaacgcctgcctaccttcgtcaacatccccaaggaccacaaccac atcgaggtgacgaggatagatgggacagtggacaaccctccgtgcctgaaggtgacccac aagacatttgggacccagcagagcaacagtgacatgctgtactgcagactgagcatgcct gtagagctccacgctcctcatgtcagtcctgacgagtctcagaaactcagtcagcctcca aaggaagatgattatggcagaattacaacgtattatcactcagtgagggtgtttgctggc caggacccagcatcggtgtgggttggctgggtaacccctgactaccattatcatagcaaa caattcagccttaacaagacacgcacggttactgtaaccctgggagacgagagaggacgc gtccacgagagtgttcggaggagtaactgctacatggtgtgtgctggagatgttgtcggc tcctcccactcctcatcccggtcaaacatcgacctggagattggctgtctcgttgacctg gcaacaggctttctctccttcacagccaatggcaaggagctggcgaccacctatgaggtg gagtccaacactaagctgttccctgctgtgtttgtgcgtcccaccagcaccaacctcttc cagtttgagtttgtcaagatcaaggccgccatgcccctgtcgtcagccatctttaagagt gaacagcgtaaccctgtgccccagtgtccaccacgtctggacgttcagaccatcgtagca gtgctgtggagccgtatgccaaacaccttcctcaccgtggagaccgccagggtctcagag agacacggctgggtggtgcagtgtctggagccactgcagatgatggctgttcatatacct gaggaaaacaggtgtctggacatcctggagctatcggagaacgagggtctgaggaagttc cactaccacaccctgatgctctactgtgccctctgcgcattgggcaacacccgcgtggca cacgccctctgctcccacctcgaccaatcacagctgctctacaccatcgacaaccaatac ctgtccggcatgctgagagagggattctataatgttcttatgagcatccacctggagaca gcaaaagaagctcgtctgatgatgaacaatgagtttatcatccccgtgaccgatgagacg cgctccatcaagctgttccctgacgagtccaagagacactctctacccggggtaggcctc agcacctctctgaaaccacgcctcatcttctcccctctctccttcatcaccaccaagaaa cagcagcacctccacagtccccagatccccctgggtatcctgaaggagaaggccatcagt atgctgactgaggcggtgcagggaggaggcagtcacatcagagacccagtaggaggcagt gtggagtaccagtttgtccccatcctcaagctgatcgggaccttgctgatcatgggggta ctcaccagcgaggaggtgaggctgatcctgctcctcattgaccctaatgtgttcggggag ccagaggaggaggaggtggaggcagcatcagcaggaggaggagagaaggaggaggtgagc agcaacgaggagaaggctgtggaggctggtgaggaggagaccaaggaggtcaaaccgacc gtgaagggactgctggagaagacactgcctgagtctgtcaaacgacagatgtgtgagctg ctgcactacttctgtgactgtgagttgaagcagcgtatcgaggccatcgtgtccttctca gacagcttcgtgtccaagctgcagtacaaccagaagttcaggtacaacgagttgatgtta gccctcaacatgtctgctgccgtcaccgccaagaagaccaaggagttccgctcccctcca caggaacagatcaacatcctgttaaactttgctgctggggaggactgtccctgtcctgaa gagattcaggaggacctctacaaatttcatgatgagctgagactgcactgcggcatccca gtggaggaggaggaggaggaggaagacacgtctataaagggtcgtctgctggccatgctc tataagatcaaggggccgcccaagaaactagaggaggaaactacggaagaggaacaggct gctcctaccaacctgaaggagttgatcagccagaccatggctagctgggctcaggagtgc agcatccaggacccagagctggttcgtgtgatgttcagcctgctgagacgtcagtatgac ggcattggagcgctgctcagggccatgaagaagagttacaccatctctgctgtgtcagta caggactgtgtcaacctcctggcctctctgggccagatcagatcactgctgtctgtacgc atggggaaagaagaggagaaactcatgatcgacggactgggtgacataatgaacaacaag gtgttctaccagcaccccaacctaatgagagtcctggggatgcatgagactgtcatggag gtgatggttaacgtgctgggaggagacaagtcacaggagatagcgttccccaagatggtc gccagctgctgccggttcctgtgttacttttgtcgtatcagccgtcagaaccagaaggcc atgtttgaccacctcagctacctactggagaacagctctgtcggactggcctccccagcc atgagaggatctactcccctggacgtagcagcgtcttcagtgatggacaacaacagcctg gccctcgctctggaggagcctgaccttgagaaggtggtaacctacctggcaggctgtggt ctgcagagctgtgccatgctcctggctaaaggataccctgacattggctggaaccccata gagggagagagatacctgtccttcctccgcttcgctgtcttcagcaatggtgagagtgtg gaggagaactctaacacggtggtgaagttgctgatcaggcgtccggagtgttttggtccc gctctgagaggagaggggggcaacggcctgctggcggccatgctggaagccattaagata tccgaggaccctgctctggacctgccctctacagctgaaggagaaccttctgggtctggt gaggatgaggaggaagaggttgcccacacaggaaacgccatcatgtctttttactctgcc cttattgacctgctgggacgctgcgcccctgagatgcacttgatcaacaagggtaaaggc gaggcattgcgtatccgtgccatcctgcgctccctggttcctaccacagacctagtgggc atcatcagtataccactcaagatgcctatcgtcaataaagacggtagtgtgacagagcca gacatgtcggctagtttctgtccggaccacaaggcccccatggtgttgtttctggaccgc gtgtacggcgtggaggaccagagctttctgctacacctgttggaggtgggcttcctgcct gacctccgcgcctccgcctccctggacacggatgtgctgagcaccacagagaccgctctg gccatgaacaggtacattggttcagccctgcttcccctgctgaccaggtgtgctgaccag ttctctggcaccgagcactacgcagcgctcatcgactctacgctccacactatctatcgg ctgtccaagggacgctccctcaccaaggcccagagagactctatcgaggagtgtttgctc gcaatctgcaaacacctgcgtccctccatgatgcagcagctgctgagacgtctggtgttt gatgttcccctgctggcagagtactgcaagatgccactcaggctgctgactgaacactat gagcagagctggatgtactactgtcttccctcggggctggggagctccggcatggcctca gaggaagaactgctgctcaccaaaaaactcttctggggaatattcgactcgctctcaaca aagaagtttgactctgacctgttcaagactgccatggcctgtctgagtgccattgctggg gcattaccacctgactatatggatgccagccccggtgtcaccctggagaagcaggcgtct gtggatgcacacggcaacttcgaccccaaacccatcaacactgccaatatgtcccttcca gagaaactggactacatcgccaacaagtttgcagagcattcccacgtcaaatggtcctca gagaaggtgacagcgggatggaaaatgggagagtgcgtagatgatgatgccaaaactcac cctctgctgaagccttacaagtcactcagtgagaaggagagggagacgtaccgctggcca gtgaaggagtctctaaagagtatgttagctatgggctggaacatggagaggaccaaagag ggagaggccatgttaatcaggaaacaaagcaagatctcagagtccactcaggataacgat aacgaattcatcccggaaccaccattggatctgaacaatattactctatccagagagttg caggggatggtggaggtagtagcagagaactaccacaacatctgggccaagaagaagaag gctgagctgaacagtaaaggaggagggagccacccattgctggtgccctatgacactctg acagccaaggagaagtacagagacagagagaaggtccaggatctctttaaatttcttcag atcaatggatacactatcaccagaggtctgaaggacatggagcaagactcatcgtccatg gagaagaggtttgcttacacgtttctcaagaggttgctgaagtatgtggactcggctcag gagttcatcgcccacctagaggccatggccaccagcggaaagacagacaaatcgcctcac gatcaggaaatcaagttcttcgccaaggtgctgctacctctcatagacatgtactttaag aatcacagcatgtacttcctgtcctcgcccagtaagaacctgagcagcagtggctacgcc tctaacaaggagaaggagatgatcaccagcctgttctgtaagatggcagctcttgtcaga cacaggatttccctctttgggagcgactcggctattatggtgagctgtctacacatcctg gctcattccctcgacacaaggacggtgatgaagtcaggctcagagatggtgaaggctggg gtcaggacattatttgagaatgcagcagaggacctagagaagaccctggagatgctgaag ctggggaagttcagccagtcccggagccagatgaagggcttgtcccagaacatcacctac gccaccaccgctctgctgcccatcctcacagccctgttcgaacatgtcaccatgcacaac tttggagtctgcctgcttgtggatgatgtccagctgtcgtgctatcgcattgtgacgtgt ctctactcattgggcacggggaaacacatcttcatggagaggcacctaccagccttaggg gagtgtctggccaccctggtaggagccatgcctgtagctttcctggagcctgatctcaat gctcacaaccccctgtctgtcttcaacaccaagacaccgcgagagagggccatcttgagt atgcctgactctgtggaggagatgtgttcagacatgcctcgtctggatcgcctgctgaag gacatcaacgacatctcagagtctggagcacgctacacagagatgccacaggtgattgag gtgatcctgcccatgttgtgtaactacttgtcctattggtgggagagaggaacagagaac tctgctccacacacagcctgctgcaccaccgtgtgctcccaccacctcagcatcatcctg gggaacatcctcaagatcctcaacaacaacctgggcatcgacgacgctccctggatgaag aggatcgcagtctactcccagccaatcatctgtaaggctgcagcggacctcctgaagagt cacttcctgcccactctggagaaactcaggaaaaagacagtcaaggtggtggcagaggag gagctgctgaaggctgacattaaaggagacactcaggaagctgagcttctcgttctggat gagtttgctgtcctctgtagagacctgtacgccttctacccaatgctcatccgctacgtg gacaacaacaggtccagatggttgaagaggcctgatgctcagtccaacgagctcttcact atggtggcggagatcttcattctgtggtgcaaatcacacaacttcaaaagggaagagcag aactttgtagttcagaatgaaatcaacaacctgtctttcttgactggggaacataagacc aagatgtccaagtcaggtggtgaccaggataggaagcacaagaagcggcgtggagagtta tactctgtccagacctctctgatcgtagccgcactgaagaagatgctgcccatcggactc aacatgtgcaccccaggagaccaggagctcatctcactggccaagataagatacagtctg aaagacacagacgatgaggtgaaggatcacttgcgtgagaacctacatcttcaggacaag tctgatgacctggcagtgcagtggcagatgaacctgtataaggatgtagtggtggtgggg agtgaggaacatgcagacccagaacaaactgtggacagaatacaaagcatctccgctgca gtcttccacctggagcaggtggagcagcctctgaggatgaagaagtgtgtgttccagaag ttgctgtccaaacagcgtaaacgtgccgtggtggcctgcttccgcatggctcctctctac aacctccccaggcatcgttctattaatctcttcgtgttgggctatgtgagactatggata gagacagaggagtactcctttgaggagaggctagtgcaggacctagcaaaaaccccaatg aagatcgtggaggaggaggaagaggaggaggttgagattcagccagaccctcttcatcag cttatccttcacttcagccacaacgccctcacagagagaagtttcttggaagaagatccg ttatatattgcgtatgcagacatgatggcaaagagttgtgcagaggatgaagaggaggaa gaagaggaagaggggaaagagaagacatttgaggagaaagagatggagaaacagaagatc ttgtaccagcaggccaggctccacgcccgcggggctgctgagatggtgctacagatgatc agcgccagtaaaggtcgactaggtcctatggtgacctgcaccctcaaactgggcatctcc atcctcaacggaggcaacgtgctggtccagcagaaaatgctggattatctgaaagagaaa agagatgcaggctttttcaagagtttgtcaggcctcatgcagtcctgcagtgtcctggac ttaaatgcctttgagagacagaacaaagcggaaggtctggggatggtgacagatgaagga tccatcaacagtgagcggggttccaaagtgctgacgaatgatgacttcactaaagatctc ttcaggtttttacaactgctctgtgaggggcacaacggagatttccaaaacttcctaaga acacaaacagggaacacgttgacagtcaacattatcatcagcacagtggactacctgcta cgccttcaggaatctatcagtgacttctactggtattattctgggaaagacattatcgac gaggcaggacaggtcaacttctccaaagccttagctgtcgcaaagcagatctttaactca ctcactgagtacatccagggcccatgtattgggaaccagcagagtctggcccacagcaga ctgtgggatgcagtggtgggattcctgcatgtgtttgccaacatgcagatgaaactgtcc caggactcgtgtcagattgagctgctgaaggagttgatggatcttcagcaggacatggtg gtgatgatgctgtcactgctggagggcaacgtggtgaatggaacgattggaaagcagatg gtggacactctggtggagtcctccagtaacgtagagatgatcctcaagttctttgacatg ttcctcaagatcaaggacctgaccacctctgacaacttcagggagtatgaccctgataac aagggggtcatctccaaaaaagatttccagaagtccatggagaaccagaagcagtacacc cagtcggagattgagttcctgctctcctgtgccgaggccgatgagaacgacatgttcaac tacgaggagtttgtggagcggttccacgagccagccaaagacattggcttcaacatagcc gtgctgctcactaacctctctgagcacatgcctcacgatccccgtctggccaccttcctg gaaccggccgagagcgtgctgaactactttgagccatacctgggccgcattgagatcatg ggtggagggaagcgcatcgagagggtctactttgagatcagcgagtccagccgcacacag tgggagaagccacaggtcaaagagtccaagagacagttcatctttgacgtggtcaacgag ggtggagagagcgagaagatggagatgtttgtgaacttctgcgaagacaccatctttgag atgcagctagcgtctcagatctcggagccagaagtggtggagcgcccggaggaggaagag gaggaggtgcacaaccttctagaagagctggctgagcaagaagaggagagagagctggag gcttcctcggctttcaccatggtctgcgtctccgctaagaagaagatctccaacttcaga gagatgctgaccttcaagagcctcaagaagcagtacaagaagtccaagaagctgagcatg aaggaggtgatccttgggttcttctccttcttctggacactctttgcagggttcttcaag gggatctacagcctcatcttcggattcttccacctcatctggtcatccatgttcggagga ggcctcgtcgaaggagccaagaacatgaaggtgacagacatcttgggcaatatgcccgat cccacccagttcggtatccacggtgacgtgttggagacagagaaggtggaggtgagtgac tcggtgtcgggcggaacagaccaggccatcaaaccatcggacaaggcagagcaggacatc ttaatggagatgattaatccgatgccaaagaaaggggaagggttaaaacatgttgatcct ggactgggagacgtctctgagaatctgaccgctgagaccaccgccactgtggagaagaag aaggctgcttctgaaccaacggagtcggaaccagagaaagcagacacagagaagaaggaa aaggaagacaaggtcaaggtggagcagcctaaagaggaaatggctcaggataagcccgtt ctcaagtccagaaacggccaatcaaaggaggctcctacttccttctttgccagcttcttg gctgggctggaggtctaccaggccaagatgctgaacacgctggctcgaaacttctacaac atgcgtttcctggctctgtttgtggcgtttgccataaacttcattctactgttctacagg gtgactgctgctgaggatgatgaggatgactcctggactagttctgatgatgaagatgaa ggtggtgaggagtactttgtcctggaggagagtacaggctacatggcccctattctgtgt ttcctggctgtgttccacactgccctctctatcctctgtttggttggctactactttctc aaggtgcctctggtggtgtttaagagagagaaggggatcgccaggctgttggagtttgaa ggtctctacatcacagagcagccggcagacgatgacatcatgggacagtgggaccgcctc gtcatcaacaccccatccttccccaataactactgggacaagtttatcaaacggaaggtc attaataagtatggagatctgtatggggctgagcggatagctgagctgttgggtctggat aagagcgccctggacttcgaccctactcaggagaccgtggtggaggcggcttctcttgta tcctggttgagctctatcgacaccaagtaccacatctggaaaatgggagtggtgctgact gataactcgttcctgtacctgatctggtacgccaccatgtccatcctggggcactacaac aacttcttcttcgctgcccatctgctggacatcgccatgggcttcaagaccctccggacc atcctgtcctccgtcactcacaacggaaaacagttggtgctgactgtagggctgttggcg gtggtggtgtatctgtacactgtggtggccttcaacttcttcaggaagttctacaacaag agcgaggacgaggacgcacctgacatgaagtgtgacgacatgatgacttgttatctgttc cacctgtacgccggggtgagggccggcggtggtattggtgatgagctcgaggacccggca ggagacccctacgagctgtggcgtatcctctttgacatcaccttcttcttcttcgtcatc gtcatcctcctggccatcattcagggtttgattattgatgcgtttggggaactgagagac cagcaggagcaggtgaaggaggatatggagactaaatgcttcatctgtggaattggaaac gactactttgacacgacaccccacggctttgagacccacaccttacaagagcacaacctg gccaactacctcttcttcctgatgtacctcatcaacaaggacgagactgaacacactggt caagagtcgtatgtgtggaagatgtaccaggagagatgctgggacttcttccctgctggg gactgtttcaggaagcagtatgaggacctgcttgggtag

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