Streptomyces sp. WP-1: QHG49_00930
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Entry
QHG49_00930 CDS
T10379
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
Organism
strw Streptomyces sp. WP-1
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
KAsynt_C_assoc
PKS_DE
PP-binding
adh_short
Epimerase
CurL-like_PKS_C
GDP_Man_Dehyd
Polysacc_synt_2
Thiolase_N
RhiE-like_linker
NmrA
RmlD_sub_bind
DUF7080
SDR
Docking
Motif
Other DBs
NCBI-ProteinID:
WKE67698
LinkDB
All DBs
Position
complement(223568..242191)
Genome browser
AA seq
6207 aa
AA seq
DB search
MSNDDKLRDYLKRVMVDLRQTRRQLGELEAKDTEPVAIVGMACRYPGGVASPEDLWRLVA
SGGDGISGFPTDRGWDLGALYDPEPGRTGRSYVREGGFLHDAGDFDPAFFGISPREALVM
DPQQRLLLETSWEAFERAGIDPVTARGTRAGVFVGTNGQDHAYLQRPGDSDIEAHLVTAN
TAAVVSGRISYALGLEGPAVTVDTACSSSLVALHLAAQALRRGECSLALAGGATVMATPN
TFVAFSAQRGLSPDGRCRAFSATADGTGMSEGVGVLLLERLSDARRLGHDVLAVIRGSAV
NQDGASNGLTAPNGPSQERVIRQALENARLTASQVDAVEAHGTATTLGDPIEAEALLATY
GQEHPEDRPLWLGSVKSNLGHTQAASGVAGVIKMVMAIRNGVLPRTLHVDAPTDQVDWSA
GGVRLLTEAVDWPESDHPRRAAVSSFGVSGTNAHTIIEQAPPLEAEPATEPAEAPAAGVR
PWVLSARTEAALRAQAQRLLAFVEDHGRGCAPADIGFSLATTRTAWDRRAAVVGGSLAEL
TEGVRALASGTPSATVVQNTGRLGDRTGFLFSGQGSQRLGMGRELYDAFPAFAAAYDEIR
AHLDVTLDLDAEQLNRTGHTQPALFALEVALFRLLESWGVRPDYVAGHSVGEIAAAHVAG
VLSLQDAAKLVSARAALMQALPEGGAMAAVEATEDEVLPYLTGRVGIAAVNGPRSTVVSG
AEDEVAAIAEAFAAQGRRTSRLKVSHAFHSPLMDPMLDEFARAIGDLTFNEPRIPVVSNL
TGRLAEPYTPEYWVRHVREAVRFADGVHTLHELGVTTFVEIGPGGVLSGMAQGCADGIVT
IPVLRADRPEPRAVVTALAELHVHGASPDWGALFPGARRVDLPTYAFQQQRYWLETPEAE
TAAVDAVDADFWASVEREDAESLAATLELSPDELDVVVPKLSAWRRRRREQSAVDGWRYH
LTWQPLNGLSAGDLSGSTWLFVANEGDEWARTVHAALTGRGARLIPLTVDATADRALLAG
ELARAGSFDGVLSLLATDETPSPAHPALSQGLARTVALAQALGDAGIDAPLWCATRGAAA
TGRSDDAPLSAVQHQVWGLGRTLALEHPHRWGGLIDLPATVDERAAGRVAAVLAQGTGTM
DAPGSGAMDGEGTGATDGPGEREDQVAVRASGVFTARLDHARGGTGRPWSPRGTVLVTGG
TGALGGHIARWLAAAGAEHLVLTSRHGADAPGAPALQAELEELGARVTLAACDIADRDAV
AALLAEHTVTAVFHAAGVPQFTPFDELTPDDFARTLAAKAHGATHLDELLGDQELDAFVL
FSSIAGVWGSGGQTAYAAANAHLDGLAARRRARGLTATAIAWGPWADGGMVTDADEAHLR
RRGVVTLPAALAVTAVQRALDCDDTAVVVADIDWERFIGPFTLGRPSALLSDVPEVRRAR
TAAPAGAGTGAASLTARLAELPQAERSRTLLDLVRAHVAAVLGHSGSGEIEPDRAFKDLG
FDSLTAVELRDRINAATGLALPPTLVFDHPSAGALARFLESELLGARTAVPQERGRHPAD
DEPIAIVAMSCHLPGGVDSPEALWDLVASGGDAISGFPEDRGWDVEGLYDPDPERPGKTY
ARDGGFLYGATGFDAGFFGISPREALAMDPQQRLLLETSWEAFERAGITPGRLRGSRTGV
FVGMAYQGYGADAHRTPEGVEGHRLVGGASSVVSGRVAYTFGLEGPAVTIDTACSSSLVA
LHLAMQSLRAGECTMALAGGVTVMASPNVFVEFSRQRGLSPDGRCRAFGADADGTGWSEG
VGVVLVERLSDAVRNGHEVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALASAGLTP
ADVDAVEAHGTGTKLGDPIEAQALLATYGQDREQPLLLGSLKSNIGHTQAAAGVAGVIKM
VMAMRHGVLPRTLHADEPTPHVDWSTGAVRLLTEAVDWPASDRPRRAAISSFGVSGTNAH
TIIEQAPAAAELPPTPDSGALVPWILSGKSEPALRAQAARLAGHLDATDGWTAPDIGYSL
ATRETFEDRAVLLAQDPAELRHALTALAGGEPAPNVILGRARSEGKVGFLFSGQGSQRPG
MGRELYEAFPVFADAYDEVCARLETPFDVDAESLHQTGNAQPALFAVEVALYRLLESWGV
RPDYVAGHSVGEIAAAHVAGVLSLDDAVKLVSARAALMQALPGGGAMVAVQATEEEVLPH
LTEQVGVAAVNGPRSVVLSGAEGAVLEIAEVFARQGRRTSRLKVSHAFHSPLMDPMLDEF
ARTIGDLTFNEPRIPVVSNLTGRLAEPYTPEYWVRHVREAVRFADGVHTLDESGVTTFVE
IGPGGVLTALTQGCLDDTAAVPVLRGDRPERQAVVAALAELYVRGASPDWRALLPGAHRV
TLPTYAFQHERYWLAGDEDPAAAAGDPADAADSGFWDSVEREDAESLAATLGVSADASLS
ALLPRLSAWRRQRRERSVVDGWRYRVTWKPLGALPQPGVTGAWLLVVAEENEWTASVRGA
LTGRGPAPVTLVAGPGTDRRTLARELADIGPVTGVLSLLADADADTNADSDSDTETAPAG
PPGLSYGLAATLCLTQALGDAGIDAPLWCATRGAVATGRSDRVDRPLQSQVWGFGRAAAL
EHPRRWGGLIDLPDLLDARTAARLTAVLGQRAEDQVAVRASGVYGRRLVRATRTTHPAPE
WSPRGTVLITGGTGALGGHVARWLAGAGAEHLVLTSRRGLDAPGAAALQAELEETGVRVT
VVACDMADREALAALLAEHPVTAVVHAAGVGDHAMIEDSDPAGFARTVSAKAAGATHLDE
LLADEELDAFVMFSSGAGIWGGASQAAYAAANAYLDALAEHRRARGRTALAVSWGGWAEG
GMAGVGDGEEMLRRRGLPPMRPALALSALQQALADDETTLTVADFDWQRFIGPFTVTRPS
ALFSDVPEAARALDAPAAGGADTGNALAARLAGLPAAERDRTLVDLVRGHAAAVLGHDGS
AAVAPDRAFNDLGFDSLTAVDLRNKLTADTGLKLPTTLVFDYPNATTLAQFLRTELLGAQ
DTARPEGRTAADGDEPIAIVAMSCRLPGGVGSPEDLWRLVTSGGDAISGFPEDRGWDVEG
LYDPDPGTPGRTYARDGGFLYDAGDFDAALFGVSPREALAMDPQQRLLLETTWEAFERAG
IDPAAMKGSRTGVFVGMSYQGYGAGLPEVPEGVEGHLLTGSAASVVSGRVAYTFGLEGPA
VTVDTACSSSLVALHLAIQSLRGGESTMAVAGGVNVMAVPAAFVEFSRQRGLAADGRCKA
FGAGADGTGWAEGVGVVLVERLSDAVRNGHEVLAVVRGSAVNQDGASNGLTAPNGPAQQR
VIRQALASAGLTPADVDAVEAHGTGTKLGDPIEAQALLATYGQDRERPLLLGSLKSNIGH
AQAASGVAGVIKMVMAMRHGVLPRTLHADEPTPHVDWSAGAVRLLTEPVDWPEADRPRRA
AISSFGVSGTNAHTIIEQAPTAEPAPVAPVEVTSPTVPWVLSGKTEAALRAQAERLLALA
ADGAGPSLTDTAFSLATTRAALEHRAAVVGADHDRITEGLRALACGAPAPGVALGRADTG
QVGFLFSGQGSQRVGMGRELYDAFPVFAAAYDEACAHLDRHLDRPLREVAFGENGHDDGA
DLNRTAFTQPALFAHEIAVHRLLESWGVRPDYLAGHSVGEIAAAHVAGALSLEDAATLVT
ARAALMQALPAGGAMIAVQATEDEVRPHLTDGTDIAAVNGPESVVVSGTKDAVTAVADLF
ARQGRKTNRLTVSHAFHSPLMDPVLADFTRVVSGLRFETPRTPVVSNLTGELVDTYTPDY
WVRHVREAVRFADGVRTLGELGVTTFVETGPGGVLSAMTQGCLDDAVTVPSTRSGSAEPE
AITGAVARLHVLGVPVDWAAFFAGRGARRAELPTYAFQHQRYWLRTTAPTATAAPTDAVE
AGFWETVEREDAQSLAATLDLPAEQLDAVLPRLSAWRRQRRRESAVEGWSYDTSWKPLSG
LRTHELPGDWLFLTTAETRSDEAPSGGSSSGAEGPWPGEDASAAAEPTAAEWASAVADGL
TARGARLIRVTVDPAADRDALLRQLGDVVGEFPVDGVISLLGADERPHTAHPALSVGTAL
TLALVQALGDAGIGAPLWALTRSAMSTGRADPVPSASQHAVWGLGRVAALEHARRWGGLI
DLPDTIDDRVTGRLAATLTQSAEDQVAIRARGVFGRRLTQSRRLPQATARRDTGAAHGWS
PRGTVLITGGTGALGGHVARWLAGAGAEHLVLTSRRGLGAPGAAALQAELAESGVRVTVA
ACDVADREALAALLAEHPVNAVVHTAGVDHLDPLETMTPDAFADVLSAKAAGALHLDALL
DGRPLDAFVLFSSIAGVWGSGHQAAYAAANALLDGLAEHRRARGLPATAVAWGPWAGGGM
AEGDGADERLRRRGLLPMPAPLAVAALGRALESGAATTTVADIDWDRFLPPFTMSRPSAL
LGDLPQAERIRTADNTPDEPGAATASPLADRLTKVPEAEQHTLLVDLVRTHAAAVLGHSG
IGEVEADRAFKDLGFDSLTAVELRNRLNAETGLNLPATLVFDHPNAQALARQLRTEITGR
TPSAVDEATLATAPDDEPIAIVGMACRYPGGVRSPEDLWRLVASGGDAVGEFPGDRGWDV
DGIYDPDPQAAGKTYARHGGFLYDAGEFDPGFFGISPREAVAMDPQQRLLLETTWETFER
AGIDAESVRGSRTGVFVGSGYQDYAATAFHAIDDSEGFFGTGNSASIMSGRIAYTLGLEG
PAVTVDTACSSSLVALHWAVQALRGGECSMALAGGVMVMSTPRAFVEFSRQRGLSPDGRC
KAFGAGADGTGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPAQ
QRVIRQALTSAGLTSADIDAVEAHGTGTTLGDPIEAQALLATYGRERPEGRPLWLGSLKS
NIGHAQAAAGVGGIIKMVMAMRHGVLPRTLHADEPTPHVDWSAGAVRLLTEPVDWPEADR
PRRAAISSFGVSGTNAHTIIEQAPPAEAEESISASGLLPWVLSAKSAAALRDQARRLLAQ
VRDDTSPADVGFSLATTRTALRHRAAVIGETGAELRHELGLLAAGTPSPGVVQGRPGGKV
GFLFSGQGSQRLGMGRELYEAFPVFADAYDAVCARLETPFDIDAESLHQTGCTQPALFAV
EVALFRLLESWGVRPDYVAGHSVGEIAAAHVAGVLSLDDAVKLVSARAALMQALPGGGAM
VAVQATEDEVLPHLTDGVGIAAINGPRSVVVSGTEDAVLTVAEAFAAQGRKTSRLKVSHA
FHSPLMEPMLDEFAQAVHGLTFNEPRVPVVSNLTGRLAEPYTAEYWVRHVREAVRFADGV
RTLHDLGVTTFVEVGPGGVLSGMAQGCLDEAVTVPVLRGERSERRALVTALAQLHTYGVA
VDWSVFFAGARKIDLPTYAFQHERYWVEAPEAVADAVVDPVDAEFWDTVEREDLRALADT
LDIDAADTFGDVLPRLSSWRRQRKEQSAVDSWRYGITWKAIPDPAPQSPAHNGGVWLVPV
SAAHLGDDWVTACLRGLAERGLTTLPVPVEPATDRAALTAQLAAVVGEETVAGVLSLLAV
DGEAAPVAAALTVGVALSVLLVQALGDAGIGAPLWCVTRNAVGVSPAETVADPHQSQIWG
LGRVAALEHAERWGGLVDLPGTVDDRIAGRLVAVLGQSAEDQVAIRERGVFARRLSRLPA
ARSERSWSPRGTVLITGGTGALGGHVARWLAGAGAEHLVLTSRRGLDAPGAAALQAELAE
SGVRVTVAACDVADREALAALLAEHPVDAVVHAAGTAEAGMLAETSLDDFAATVAAKALG
ALHLHELLGERELDAFVLFSSISGVWGGGGQAAYSAANAFLDGLAQHRRSLGRTATAIAW
GPWAEGGMVADAGDEERLRRRGLTTLRPDRAIAALHGALSGTDGTVTVADVDWARFVVPF
TVSRPSALLGDLPEVRNALAERRPPTGQGAEPSALREKLATLSEDERRRLLVDTVCAHAA
AVLGHSGATAVEPDLAFRDLGFDSLTAVELRNLLTADTGLTLPATLVFDHPTPEAIARHL
DGELTGGTSPDEVSVFGELDRLESVIGTAATAEETVRSGVRRRLQELLALVNSAGEQHTG
SADAQRQLQDATVDDIFDLIDQDLENS
NT seq
18624 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaacgacgacaagctcagggactacctcaagcgcgtgatggtggacctgcgccag
acccgcaggcagctgggtgagctggaggcgaaggacaccgagcccgtcgccatcgtcggt
atggcctgccgctacccgggcggtgtcgcctcgcccgaggacctgtggcggcttgtcgcc
tcgggcggcgacggcatctccgggttccccaccgaccggggctgggacctcggcgcgctc
tacgaccccgagcccggccggaccggccgcagctatgtgcgcgagggcggattccttcac
gacgccggggacttcgaccccgcgttcttcgggatctcgccgcgcgaggccctcgtcatg
gacccgcagcagcggctgctgctggagacctcgtgggaggcgttcgaacgcgcgggcatc
gatcccgtcaccgcgcgcggcacccgggccggtgtgttcgtcggcaccaacggacaggac
cacgcctacctccagcggccgggcgacagcgacatcgaggcccacctcgtcaccgcgaac
accgccgccgtggtctccggccgcatctcctacgccctcggtctcgaaggcccggcggtc
accgtcgacacggcctgctcgtcctccctggtcgcgctccacctggccgcgcaggcgctg
cgccggggcgagtgctcgctcgccctggcgggcggtgccaccgtgatggccaccccgaac
accttcgtcgcgttcagcgcccagcgcggcctgtcgcctgacggccgctgccgcgcgttc
tccgccaccgccgacggcacgggcatgtccgagggcgtcggcgtcctgctgctggagcgg
ctgtccgacgcccgccggctcggccatgacgtcctcgccgtcatccgtggcagcgccgtc
aaccaggacggcgcctccaacggcctcaccgccccgaacggcccctcccaggaacgggtg
atccggcaggcgctggagaacgcccgtctgaccgcctcccaggtcgacgcggtcgaggcg
catggcacggccaccaccctcggcgacccgatcgaggcggaggcgctgcttgccacctac
ggccaggagcacccggaggaccggccgctgtggctcgggtccgtcaagtccaacctcggg
cacacccaggcggcttccggcgtcgccggggtcatcaagatggtcatggccatccgcaac
ggcgtgctgccgcggacgctgcacgtggacgcgccgaccgatcaggtcgactggtcggcg
ggcggggtacggctgctcaccgaggccgtcgactggcccgagtccgaccacccccggcgc
gccgccgtctcctccttcggcgtcagcggcaccaacgcgcacacgatcatcgagcaggcc
ccgcccctcgaagcggagcccgccaccgaaccggcggaagcccccgccgcgggtgtgcgg
ccgtgggtgctctcggcgaggaccgaggccgcgctgcgcgcccaggcccaacgcctgctc
gccttcgtggaggaccacggccgcggctgcgcaccggccgacatcggcttctccctcgcc
acgacccgcaccgcctgggaccgccgggcggcggtcgtcggcgggagtctggcagaactc
accgagggcgtacgggccctggcgtccggcaccccctcggcgactgtcgtgcagaacacg
ggccgcctcggcgacaggaccgggttcctcttctccggccagggctcccagcggctcggc
atgggccgtgaactgtacgacgccttccccgcgttcgccgccgcctacgacgagatccgc
gcccacctcgacgtcacgctcgacctggacgccgagcagctgaaccgtaccggccacacc
cagccggcgctgttcgcccttgaggtggccctcttccggctgctggagtcctggggcgtg
cggccggactacgtggccggtcactcggtgggcgagatcgcggccgcgcatgtggccggg
gtgctgtcgctccaggacgccgcgaagctggtgtcggcgcgtgcggcgctgatgcaggcg
ctccccgagggcggcgcgatggccgccgtcgaggcgaccgaggacgaggtactgccgtac
ctgaccggccgggtcggcatcgcggcggtcaacgggccccggtcgaccgtggtctccggt
gccgaggacgaagtcgccgcgatcgccgaggcgttcgccgcccagggccgcaggacgtcc
cggctgaaggtcagccacgcgttccactcgccgctgatggacccgatgctggacgagttc
gcccgggccatcggggacctgaccttcaacgagccccggattcccgtggtttcgaacctg
accggccgactggcggagccgtacaccccggagtactgggtacgacacgtccgtgaggcg
gtccgtttcgccgacggcgtgcacaccctgcacgagttgggcgtgaccaccttcgtggag
atcggccccggcggtgtcctcagcggcatggcgcagggctgtgcggacggcatcgtcacc
atccccgtcctgcgcgccgaccgccccgaaccccgggccgtcgtcaccgcgctcgccgaa
ctgcacgtgcacggcgcgtcccccgactggggagccctcttcccgggcgcccgccgcgtc
gacctgcccacctacgccttccagcagcagcgctactggctggagacccccgaggccgag
acggccgccgtggacgcggtcgacgccgacttctgggcgagcgtcgagcgcgaggacgcc
gagtccctcgccgcgacgctggagctgagccccgacgaactggacgtcgtcgtaccgaag
ttgtccgcctggcgacgcaggcggcgcgagcagtccgccgtggacggctggcgctaccac
ctgacctggcagccgctgaacggcctgtccgcgggcgatctctcgggcagcacctggctg
ttcgtcgcgaacgagggcgacgagtgggcccggacggtccacgcggccctcaccggacgc
ggcgcaaggctgatccccctgaccgtggacgccaccgccgaccgcgccctcctggcgggt
gagttggcccgggccggatccttcgacggcgttctgtccttgctcgcgaccgacgagacg
ccctcgcccgcgcaccccgcgctctcccagggcctcgcccggaccgtggccctggcgcag
gcgctgggcgacgccggcatcgacgcgccgctgtggtgcgccactcgtggcgcggccgcc
accggccgttccgacgacgccccgctcagcgccgtacagcaccaggtgtggggcctcggc
cgcaccctcgcgctggaacacccccaccgctggggcggcctgatcgacctgcccgcgacc
gtggacgaacgcgccgccggacgtgtcgccgccgtactcgcccagggaaccggcaccatg
gacgccccgggatccggcgccatggacggcgagggaaccggtgccacggacggcccgggg
gagcgggaggaccaggtcgccgtccgcgcctccggtgtgttcaccgcccggctcgaccac
gcccgcggcggcaccggccggccgtggtcgccgcgcggcaccgtcctggtcaccggcggt
accggcgccctcggcgggcacatcgcccgctggctcgccgctgcgggcgccgagcacctg
gtgctcaccagccgccacggcgccgacgcccccggcgcgcccgcgctccaggccgaactg
gaggagctgggcgcccgcgtcaccctcgccgcctgcgacatcgccgaccgcgacgcggtg
gcggccctgctcgccgaacacaccgtcaccgccgtcttccacgccgcgggcgtgccccag
ttcacccccttcgacgaactgacaccggacgacttcgcccgcaccctcgcggcgaaggcc
cacggcgccacccacctggacgaactgctcggcgaccaggagctggacgccttcgtgctc
ttctcctcgatcgccggcgtgtggggcagcggcggccagaccgcctacgccgccgccaac
gcccatctcgacgggctcgccgcccggcgccgggcccggggcctgaccgccaccgcgatc
gcctggggcccctgggccgacggcggcatggtcaccgacgccgacgaggcacacctgcgc
cgccgcggcgtcgtcaccctgcccgccgcgctcgccgtgaccgcggtccagcgcgccctg
gactgcgacgacaccgcggtcgtcgtggccgacatcgactgggaacggttcatcggaccg
ttcaccctcggccgccccagcgccctgctgtccgacgtgcccgaggtgcgtcgcgcccgc
accgcggcgcctgccggcgccgggaccggcgccgcgtcactgacggcccggctcgccgaa
ctgccgcaggccgaacgcagccggaccctgctcgacctggtccgcgcgcatgtcgcggcc
gtcctcggccacagcggcagcggtgagatcgagcccgaccgggccttcaaggacctcggc
ttcgactccctgaccgccgtcgaactccgcgacaggatcaacgcggcgaccggcctcgca
ctgccgcccaccctggtcttcgaccaccccagcgccggtgcgctcgcccgcttcctggaa
agcgaactcctcggcgcgcggaccgccgtaccgcaggagcgaggacggcacccggccgac
gacgagcccatcgccatcgtcgcgatgagctgccacctgcccggcggcgtcgactcgccc
gaggccctgtgggacctggtggcgtccggcggcgacgcgatctccgggttccccgaggac
cgcggctgggacgtcgagggcctctacgaccccgaccccgaacgccccggcaagacctac
gcgcgcgacggcggattcctctacggcgcgaccggcttcgacgcgggcttcttcgggatc
tccccgcgcgaggcactggccatggacccgcagcagcggctgctgctggaaacctcgtgg
gaggcgttcgaacgcgccgggatcacccccggccggctgcgcggcagccgcaccggcgtc
ttcgtcggcatggcctaccagggctacggagccgacgcgcaccgcacgcccgaaggcgtc
gagggacaccggctcgtcggcggcgcctccagcgtcgtctccgggcgcgtggcctacacc
ttcggcctcgaaggccccgccgtcaccatcgacaccgcctgctcctcctccctggtcgcc
ctgcacctggccatgcagtcgctgcgcgccggcgagtgcacgatggccctggccggcggt
gtcaccgtcatggccagtccgaacgtcttcgtggagttcagccgccagcgcggactgtca
cccgacggccgctgccgggccttcggcgcggacgcggacggcaccggctggtccgagggc
gtgggtgtggtgctcgtggagcgcctgtccgacgccgtgcgcaacggccatgaggttctc
gcggtggtccgggggagcgcggtcaaccaggacggcgcgtccaacggtctgaccgccccg
aacggtccggcgcagcagcgggtcatccggcaggccctcgcctccgccggtctcacaccg
gccgacgtggacgccgtggaggcacacggtacggggacgaagctgggcgacccgatcgag
gcgcaggcgctgctcgcgacctacggacaggaccgcgaacagccgctcctgctcggctcg
ttgaagtccaacatcggccacacccaggccgccgcgggcgtcgccggtgtgatcaagatg
gtcatggcgatgcgccacggcgtcctgccccggaccctgcacgccgacgagccgacgccg
cacgtggactggtcgacgggcgcggtacggctgctgaccgaggccgtcgactggcccgcc
tcggaccgcccgcgccgcgccgcgatctcgtccttcggggtcagcggcaccaacgcccac
accatcatcgaacaggcccccgccgcagcggagttgcccccgaccccggactccggcgca
ctcgtgccgtggatcctgtcgggcaagagcgagccggccctgcgtgcccaggcggcccgg
ctcgccggccacctcgacgcgacggacggctggacggcccccgacatcggctactccctg
gccacccgcgagaccttcgaggaccgcgccgtactcctggcccaggaccccgccgaactc
cgccacgccctcaccgccctcgcaggcggcgaaccggcccccaacgtgatattggggcgc
gcccgctccgagggcaaggtcggcttcctgttctcgggtcagggatcccaacgcccgggt
atgggacgtgagttgtacgaggcgttccccgtgttcgccgatgcgtacgacgaggtgtgc
gcgcgtctggagacgccgttcgacgtcgacgccgagtcgctgcaccagaccgggaacgcc
caaccggcgctgttcgcggtcgaggtggcgctgtaccgcctcctcgaatcgtggggtgtg
cgcccggactacgtcgccggtcactcggtcggcgagatcgctgccgcgcatgtggcggga
gtgctgtcgctggacgacgcggtgaagctggtctcggcccgtgccgcgctcatgcaggcg
ctgcccggtggcggcgcgatggtcgccgtacaggcgaccgaggaagaggtgctgccgcat
ctgaccgagcaggtcggcgtcgcggcggtcaacggcccccggtccgtggtgctctccggg
gccgagggcgccgtgctggagatcgcggaggtcttcgcccggcagggccgcaggacatcc
cggctgaaggtcagccacgcgttccactcgccgctgatggacccgatgctggacgagttc
gcccggaccatcggggacctgaccttcaacgagccccggattcccgtcgtttcgaacctg
accggccgactggcggagccgtacaccccggagtactgggtacgacacgtccgcgaggcg
gtccgtttcgccgacggcgtgcacaccctcgacgagtcgggtgtgaccacgttcgtcgag
atcggccccggcggtgtcctcaccgccctgacgcagggctgcctggacgacaccgccgcc
gtgcccgtgctgcgcggcgaccgtcccgaacggcaggccgtcgtcgccgcgctcgccgaa
ctttacgtgcgcggcgcgtcccccgactggcgggccctcctccccggcgcccaccgggtc
accttgcccacctacgccttccagcacgagcgctactggctggcgggcgacgaggacccg
gccgccgccgccggcgacccggccgacgcggcggactccgggttctgggacagcgtggag
cgcgaggacgccgagtccctcgccgcgaccctcggcgtgagcgcggacgcctcgctcagc
gcgcttctgccccggctgtccgcgtggcgccggcagcgccgcgagcggtccgtggtcgac
ggctggcgctaccgcgtcacctggaagccgctcggcgcgctcccgcagcccggtgtgacc
ggcgcctggctgctcgtggtggccgaggagaacgagtggaccgcctcggtccgcggcgcg
ctcaccgggcgcggcccggcaccggtcacgctcgtcgccggccccggcaccgaccgccgc
acactggcccgcgaactggccgacatcggcccggtgaccggcgtactctccctgctcgcc
gatgccgacgccgataccaacgccgactctgactccgataccgagaccgccccggccggg
ccgcccggtctgtcgtacggcctcgccgcgaccctctgcctgacgcaggcgctcggcgac
gcgggcatcgatgccccgctgtggtgcgccacgcgcggcgcggtggccaccggacgctcc
gaccgcgtcgaccgcccgctccagtcccaggtgtggggcttcggccgggccgccgcgctc
gaacacccgcgacgctggggcgggttgatcgacctgccggacctgctggacgcccgtacg
gcggcccgcctcaccgccgtcctcggccagcgggccgaggaccaggtggcggtccgcgcc
tccggtgtctacgggcgccggctcgtccgggccacccgcaccacccaccccgcaccggag
tggtcgccgcgcggcaccgtgctgatcacgggtggcaccggcgcgctgggcggccatgtg
gcccgctggctcgccggtgcgggcgccgagcacctggtgctgaccagccgtcgcggcctc
gacgcccccggtgccgccgcgctgcaggcggagctggaggagacgggcgtacgcgtgacc
gtcgtcgcctgcgacatggccgaccgcgaggcgctggccgcgctgctcgccgagcacccg
gtgaccgccgtcgtgcacgccgcgggcgtcggcgaccacgccatgatcgaggacagcgac
ccggccgggttcgcccgtacggtgtccgcgaaggccgcgggcgccacccacctggacgaa
ctgctggccgacgaggaactcgacgcgttcgtcatgttctcctcgggcgccggcatctgg
ggcggcgccagccaggccgcctacgcggcggccaacgcctacctggacgccctcgccgaa
caccggcgggcacgcggacgcaccgcgctcgccgtctcctggggcggctgggccgagggc
ggcatggccggggtcggcgacggcgaggagatgctgcgccgacgcggcctgccgccgatg
cgccccgccctcgccctctccgcgctccagcaggcgctggccgacgacgagaccaccctc
accgtcgcggacttcgactggcagcggttcatcggccccttcaccgtcacccggcccagc
gccctgttctccgacgtccccgaggcggcccgcgccctggacgccccggccgccggtggc
gccgacacgggcaacgcgctcgccgcacggctggccgggctgccggcggccgagcgggac
cgcaccctggtggacctcgtccggggccacgccgccgccgtgctcggccacgacggcagc
gcggccgtggcaccggaccgggcgttcaacgacctcggcttcgactccctcaccgccgtc
gacctgcgcaacaagctcacggccgacaccggtctgaaactgcccaccaccctggtcttc
gactaccccaacgccaccaccctggcccagttcctgcgcaccgaactgctcggcgcgcag
gacaccgcccggcccgaggggcgcaccgccgccgacggcgacgaaccgatcgccatcgtg
gccatgagctgccgcctccccggcggagtcggctcacccgaggacctgtggcggctcgtg
acgtccggcggcgacgccatctccgggttccccgaggaccgcggctgggacgtcgagggc
ctctacgaccccgacccgggcaccccgggcaggacgtacgcgcgcgacggcggattcctc
tacgacgcgggcgacttcgacgccgcgctgttcggggtctcaccgcgcgaggcgctcgcc
atggacccccagcagcgcctgctcctggagaccacctgggaggcgttcgagcgcgccgga
atcgacccggccgccatgaagggcagccgcaccggtgtgttcgtcggcatgtcctaccag
gggtacggcgccggcctcccggaggtccccgagggcgtcgagggccacctgctcaccggc
agcgccgccagcgtcgtctccgggcgcgtggcctacaccttcggtctggagggcccggcc
gtcaccgtcgacacggcgtgctcctcgtcgctggtcgccctgcacctcgccatccagtcg
ctgcgcggcggcgagagcacgatggccgtcgcgggcggggtcaacgtcatggccgtaccg
gccgcgttcgtggagttcagccgccagcgcgggctggccgccgacggccgctgcaaggcg
ttcggggccggggcggacggcaccggctgggcggagggcgtgggtgtggtgctcgtggag
cgcctgtccgacgccgtgcgcaacggccatgaggttctcgcggtggtccgggggagcgcg
gtcaaccaggacggcgcgtccaacggtctgaccgccccgaacggtccggcgcagcagcgg
gtcatccggcaggccctcgcctccgccggtctcacaccggccgacgtggacgccgtggag
gcacacggtacggggacgaagctgggcgacccgatcgaggcgcaggcgctgctcgcgacc
tacggacaggaccgcgaacggcctctcctgctcggctcgttgaagtccaacatcggccac
gcccaggcggcgtccggcgtggccggcgtcatcaagatggtcatggcgatgcgccatggc
gtcctgccccggaccctgcacgccgacgagccgacgccgcatgtggactggtcggcgggc
gcggtacggctgttgacggagcccgtggactggccggaggcggaccgcccgcgccgggcc
gcgatctcgtccttcggggtcagcggcaccaacgcccacaccatcatcgaacaggcgccg
acggccgaaccggcccccgtcgcaccggtcgaggtcacctccccgaccgtgccgtgggta
ctgtccggcaagaccgaggccgcgctgcgcgcccaggccgaacgcctgctcgccctcgcc
gccgacggcgccggaccctccctcaccgacaccgcgttctcgctggccaccacgcgagcc
gccctggagcaccgcgccgccgtggtcggcgccgaccacgaccggatcaccgagggcctg
cgggccctggcctgcggagcgcccgcccccggcgtcgccctcggccgcgccgacaccggc
caggtcggattcctgttctccggccagggctcccagcgcgtcggcatgggacgggaactg
tacgacgccttcccggtcttcgcggcggcctacgacgaggcgtgcgcccacctcgaccgg
catctcgaccggccgctgcgggaggtggccttcggcgagaacggccacgacgacggcgcg
gacctgaaccgcaccgccttcacccagcccgccctgttcgcccacgagatcgccgtccac
cgcctgctggagtcctggggcgtacgaccggactacctggccggacactccgtgggcgag
atcgcggcggcgcacgtcgccggggccctctcactggaggacgccgccaccctggtgacc
gcccgtgccgcgctcatgcaggccctgcccgccggcggcgcgatgatcgccgtacaggcc
accgaggacgaggtacgaccgcacctcaccgacggcaccgacatcgcggcggtcaacggc
ccggagtccgtcgtggtctccggaaccaaggacgccgtgacggccgtcgcggacctcttc
gcccgccagggccgcaagacgaaccggctcacggtgagccacgccttccactcgccgctg
atggaccccgtgctggcggacttcacccgcgtcgtcagcggtctgcgcttcgagacgccc
cggacaccggtcgtctcgaacctcaccggcgaactcgtcgacacgtacaccccggactac
tgggtccggcacgtccgcgaggccgtgcgcttcgcggacggcgtccgcaccctgggcgag
ctgggcgtgaccacgttcgtggagaccggccccggcggggtgctgagcgccatgacccag
ggctgcctggacgacgcggtcaccgtgccctccacacggtccgggagcgccgagcccgag
gcgatcaccggcgccgtcgcgcggctgcacgtgctcggcgtccccgtcgactgggcggcg
ttcttcgccgggcgcggcgcccggcgcgccgaactgcccacctacgccttccagcaccag
cggtactggctccgcaccaccgcgcccacggccaccgccgcgccgaccgacgccgtggag
gccgggttctgggagaccgtggagcgcgaggacgcccagtccctcgccgccaccctcgac
ctgcccgccgaacagctggacgcggtgctgccccggctgtccgcgtggcgccggcagcgg
cgccgggagtcggccgtggagggctggtcctacgacacgagctggaaaccgctcagcggt
ctgcggacacatgaactgccgggcgactggctgttcttgaccaccgccgagacccggtcg
gacgaggccccgtccggcgggtcctcgtcgggcgcggagggtccgtggcccggcgaagac
gcgtcggccgcagccgagccgaccgccgccgagtgggcgtccgccgtcgccgacgggctc
accgcccgaggtgcccggctgatccgggtgacggtcgaccccgccgccgaccgggacgca
ctgctgcgccaactcggcgatgtcgtcggtgagttcccggtcgacggggtgatctccctc
ctcggcgccgacgagcggccgcacaccgcgcacccggccctctccgtcggcaccgcgctg
accctcgcgctcgtccaggccctgggcgacgccgggatcggcgccccgctgtgggcgctg
accaggtccgccatgtccaccggccgcgccgacccggtgccgagcgcatcccagcacgcc
gtctgggggctgggccgggtcgccgcgctggagcacgcgcggcgctggggcggcctgatc
gacctcccggacacgatcgacgaccgggtcaccggccgtctcgccgcgaccctcacccag
tccgccgaggaccaggtcgccatccgcgcccgaggcgtcttcggccgcaggctcacccag
agccgcaggctcccccaggccaccgcccgccgcgacaccggcgccgcccacgggtggtcg
ccgcgcggcaccgtgctgatcacgggcggtacgggtgcgctgggcgggcatgtggcccgg
tggctcgccggtgcgggtgcggaacacctggtgctgaccagccgtcgtggtctcggcgcg
cccggtgccgccgccctgcaagcggagttggcggagtcgggcgtacgggtgacggtcgcc
gcgtgtgacgtcgccgaccgcgaggcgctggccgcgctgctcgccgagcacccggtgaac
gccgtcgtccacacggcgggcgtggatcacctggacccgctggagaccatgacgccggac
gccttcgccgacgtactctccgcgaaggcggcgggcgccctgcacctcgacgcgctcctc
gacggccggccgctggacgccttcgtcctcttctcctccatcgccggtgtgtggggcagc
ggccaccaggccgcctacgcggcggccaacgccctgctcgacggactcgccgaacaccgc
cgtgcccggggactgccggcgaccgccgtggcctggggcccgtgggcgggcggcggcatg
gccgagggcgacggcgcggacgaacggctgcgcaggcgcggcctgctcccgatgcccgcc
ccgctcgccgtggccgcactcggacgggcactggaatccggcgcggcgaccaccacggtg
gccgacatcgactgggaccggttcctgcccccgttcaccatgagccgcccgagcgccctg
ctcggcgacctcccgcaggccgagcgcatccgcaccgcggacaacaccccggacgagccc
ggcgcggccaccgcctcgcccctggccgaccgcctcaccaaggtgcccgaggccgaacag
cacaccctgctggtcgacctcgtccgcacccacgcggctgccgtcctcggccacagcggc
atcggtgaggtggaggccgaccgggccttcaaggatctcggcttcgactccctgaccgcc
gtcgaactgcgcaacaggctcaacgccgagaccggcctcaacctgcccgccacactggtc
ttcgaccaccccaacgcccaagcgctcgcacgccagttgcgcaccgagatcaccggccgc
accccatcggccgtagacgaagcgaccctcgcgaccgcccccgacgacgaacccatcgcg
atcgtcggcatggcctgccgctacccgggcggggtgcgttcgcccgaggacctgtggcgg
ctggtggcctccggtggtgacgcggtcggcgagttccccggggaccgtggctgggacgtc
gacggtatatacgacccggacccgcaggcggccgggaagacgtacgcgcgccacggtgga
ttcctgtacgacgcgggggagttcgaccccgggttcttcgggatctctccgcgtgaggcg
gtggcgatggatccgcagcagcggctgctgctggagacgacgtgggagacgttcgagcgg
gccggtatcgacgcggagtcggtgcgcggcagccgtaccggagtgttcgtcggctccggt
taccaggactacgccgccacggccttccacgcgatcgacgactccgagggcttcttcggc
acgggcaactcggccagcatcatgtccggccgtatcgcctacaccctcggcctggaaggg
ccggccgtcaccgtcgacacggcctgctcctcctcgctggtcgccctgcactgggcggtc
caggcgctgcgcggcggcgagtgctccatggcactggccggcggtgtgatggtcatgtcc
accccgcgcgccttcgtggagttcagccggcagcgcgggctgtcacccgacggccgctgc
aaggcgttcggggccggggcggacggcaccggctgggccgagggcgtcgggatgctgctg
gtggagcggctgtccgacgcccgccgcaacgggcaccaggtgctggccgtcgtccggggg
agcgcggtcaaccaggacggcgcctccaacggcctgaccgcgcccaacggccccgcgcag
cagcgtgtcatccgccaggcgctcacctccgccgggctcacctccgccgacatcgacgcg
gtcgaggcgcacggtacgggcaccacgctcggcgacccgatcgaggcgcaggcgctcctc
gccacctacggccgcgagcgcccggagggccggccgctgtggctgggctcgctgaagtcc
aacatcggccacgcgcaggccgccgcgggtgtcggcggcatcatcaagatggtcatggcg
atgcgccacggtgtcctgccccggaccctgcacgccgacgagccgacgccgcatgtggac
tggtcggcgggtgcggtacggctgttgacggagcccgtggactggccggaggcggaccgc
ccgcgccgggccgcgatctcgtccttcggcgtcagcggcaccaacgcccacaccatcatc
gaacaggccccgcccgccgaggccgaggagtcgatttccgcctcgggcctcctgccctgg
gtgctctccgccaagagcgccgccgcgctgcgcgaccaggcgcgacggctgctggcccag
gtacgggacgacacctcaccggccgacgtcggcttctccctggccaccacccgcaccgcc
ctgcgccaccgggcggccgtcatcggcgagaccggcgccgaactccgccacgaactgggc
cttttggccgccggtacgccgtccccgggagtcgtccagggccggccgggaggcaaggtc
ggcttcctgttctcgggccagggctcgcaacgcctcggtatggggcgcgagttgtacgag
gcgttccccgtgttcgccgatgcgtacgacgcggtgtgcgcgcgtctggagacgccgttc
gacatcgacgccgagtccctgcaccagacgggatgcacacaaccggcattgttcgcggtc
gaggtggcgttgttccgcctgctggagtcgtggggtgtgcgcccggactacgtcgccggt
cactcggtcggcgagatcgctgccgcgcatgtggccggggtgctgtcgctggacgacgcg
gtgaagctggtgtcggcgcgtgccgcgctgatgcaggcgttgccgggtggcggcgcgatg
gtcgccgtacaggccaccgaggacgaggtgctgccgcatctgaccgatggcgtcggcatc
gcggcgatcaacggacctcggtcggtcgtggtttccggtaccgaggacgcggtcctcacg
gtcgccgaggcgttcgccgctcagggccgtaagacctcccggctgaaggtcagccacgcg
ttccactcgccactgatggagccgatgctggacgagttcgcgcaggccgtccacggcctg
accttcaacgagccgcgcgtcccggtggtttcgaacctgaccggacgactggccgagccc
tacaccgcggagtactgggtacgacacgtccgtgaggcggtgcgcttcgccgacggtgtc
cggacactccacgacctgggtgtcaccacgttcgtggaggtcggtccgggcggtgtcctg
agcggtatggcgcagggctgcctggacgaggccgtgaccgtgccggtgctgcgcggcgag
cgttccgagcggcgggcgctcgtgaccgcgctggcccaactgcacacgtacggcgtggcg
gtggactggagtgtgttcttcgcgggtgcgcggaagattgatctgccgacgtacgcgttc
cagcacgagcggtactgggtcgaagcaccggaagccgtggccgatgcggtggtggacccg
gtggacgccgagttctgggacacggtggaacgcgaggatctgcgagccctcgccgacacc
ctggacatcgacgcggccgacaccttcggggacgtactgccgaggctgtcgtcatggcgg
cggcagcgcaaggaacagtccgccgtggacagttggcgctacggcatcacctggaaggcg
ataccggaccccgccccgcaaagccctgcccacaacggcggtgtatggctggttccggtg
agcgccgcgcacctcggcgacgactgggtcaccgcctgcctgcgcgggctggccgaacgg
ggcctgaccacgctgccggtcccggtcgagccggccacggaccgggcggccctgaccgct
caactcgctgcggtcgtcggcgaggagaccgtggcgggcgtcctgtcgctgctcgccgtc
gacggcgaggccgccccggtggccgccgccctgaccgtcggtgtcgcgctgtccgtcctg
ctcgtccaggccctgggcgacgccgggatcggtgccccgctgtggtgcgtgacccgcaac
gcggtgggcgtgagccccgccgagacggtggcggacccccaccagtcccagatctggggg
ctcggccgggtggcggcgctggagcacgcggagcgctggggcggtctcgtggaccttccc
ggcacggtcgacgaccggatcgcgggccgactcgtcgcggtcctcggacagtcggccgag
gaccaggtcgcgatccgtgagcgtggggtgttcgcacggcgcctgtcgcggctgcccgcg
gcgcggagcgagcgttcgtggtcgccgcgcggcacggtgctgatcacgggcggtacgggt
gcgctgggcgggcatgtggcccggtggctcgccggtgcgggtgcggaacacctggtgctg
accagccgtcgtggtctcgacgcgcccggtgccgccgccctgcaagcggagttggcggag
tcgggcgtacgggtgacggtcgccgcgtgtgacgtcgccgaccgcgaggcgctggccgcg
ctgctcgccgagcaccccgtcgacgccgtggtccacgcggccggcaccgccgaggcgggc
atgctcgccgagacgagcctcgacgacttcgcggcgacggtcgccgcgaaggccctcggc
gccctgcacctccacgagctgctcggcgaacgggagctggacgccttcgtgctcttctcc
tccatctccggcgtgtggggaggcggcggccaggccgcgtactcggccgccaacgccttc
ctcgacggcctggcgcagcaccggcggtccctgggccgcaccgcgaccgccatcgcctgg
ggcccctgggccgagggcggcatggtcgccgacgccggggacgaggaacggctgcgccgg
cgcggcctgaccaccctgcggccggaccgggcgatcgccgcgctgcacggcgcgctgagc
ggcacggacggcacggtcaccgtggccgacgtggactgggcgcggttcgtcgtcccgttc
accgtcagcaggcccagcgcgctcctgggcgacctgcccgaggtccgaaacgccctcgcg
gagcggcgtccgcccaccgggcagggcgcggagccgtccgcgctgcgggagaagctggcc
actctgtccgaggacgagcggcgacgcctgctcgtggacacggtgtgcgcgcacgcggcg
gccgtactcggccacagcggcgccacggcggtggaaccggacctggccttccgggacctc
ggcttcgactccctgaccgcggtggagctgcgcaacctgctcaccgccgacaccggtctc
accctccccgcgaccctggtcttcgaccacccgacccccgaggcgatcgcccgccacctg
gatggcgaactcaccggcgggacaagcccggacgaggtctcggtcttcggcgaactcgac
cggctggagtcggtgatcggaacggccgccaccgcggaggagacggtccgctcgggggtg
cgcaggcggctccaggagctgctggccctggtgaactccgccggcgaacagcacaccgga
tcggccgacgcacagcggcagctccaggacgcgacggtcgacgacatcttcgatctgatc
gatcaagatctagaaaattcctag
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