Streptomyces sp. WP-1: QHG49_04295
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Entry
QHG49_04295 CDS
T10379
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
strw Streptomyces sp. WP-1
Pathway
strw00270
Cysteine and methionine metabolism
strw00480
Glutathione metabolism
strw01100
Metabolic pathways
strw01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
strw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
QHG49_04295 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
QHG49_04295 (egtA)
Enzymes [BR:
strw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
QHG49_04295 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
WKE68300
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Position
1040661..1041995
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AA seq
444 aa
AA seq
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MSDATDEGGDCTGHRTAVTEAEVDALVQGICFKNGPPRTLGVELEWLIHERDLPQRPVPP
ERLRAAHAAVRALPLGSAFTVEPGGQLELSSPPAASLMECVGTVSADLAAVRAVLDAQGL
ALVGLGHDPFHVPDRFLREPRYDAMETCLDRTGPAGRHMMRASASVQVCVDAGHEEPGPL
GHGRRWWLAHQLGAVLVAAFANSPLIGRLPTGWLSTRQLMWARIGADRAGAPPLHEEPRS
AWARHVLDAPVMCVRRDGGPWEVPEGLTFREWTRGQGPRPPTRADLDYHLTTLFPPVRPR
GHLELRMIDAQPGEDGWIVPLAVTAALFDDPQAAETAYRCVKPLAERALNLPAPHNPLWS
DAARLGLADPELREAAAACFAAALDALPRLGAGAEVTDAVAGYLERYVARGRCPADDLLD
ALPGIRTGPAGSGPAAQGRKDIPS
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
atgtccgatgcgacggacgagggtggcgactgtacggggcaccgtacggccgtcaccgag
gccgaggtggacgccctggtccagggcatctgcttcaagaacggcccgccccgcaccctc
ggtgtggagctggagtggctcatccatgagcgggacctgccgcagcgtcccgtgccaccc
gaacgactgcgcgcggcccacgccgccgtgcgtgccctgcccctcggttcggcgttcacc
gtcgaacccggcggccagctggagctgagttcgccgcccgccgcctccctgatggagtgc
gtcggcaccgtctccgccgacctcgcggccgtccgcgccgtcctcgacgcgcagggcctc
gccctcgtcggtctcggccatgatcccttccacgtcccggaccggttcctgcgcgagccg
cgctacgacgcgatggagacctgcctggaccgcaccggaccggccggccggcacatgatg
cgcgcctccgcctccgtgcaggtctgcgtggacgcgggccacgaggagccgggcccgctg
gggcacgggcggcgctggtggctggcgcaccagctgggcgcggtcctggtggccgcgttc
gccaactccccgctgatcggccggctgccgaccggctggctgtccacccgacagctgatg
tgggcgcggatcggtgccgaccgggcgggcgcgccgccgctgcacgaggagccgcggtcc
gcgtgggcccggcatgtgctggacgccccggtgatgtgcgtgcgccgggacggcgggccc
tgggaggtgcccgaggggctgaccttccgggagtggacgcgcgggcaggggccccggccg
cccacccgggcggacctcgactaccacctgacgaccctgttcccgccggtcagaccgcgt
ggccatctggagcttcggatgatcgacgcgcagccgggcgaggacggctggatcgtgccg
ctcgcggtgacggcggcgctcttcgacgatccgcaggccgccgagaccgcctaccggtgt
gtgaagcccctggccgagcgggctctgaacctgccggccccgcacaatccgctgtggagc
gacgcggcccggctcgggctcgccgatccggagctgcgggaggcggccgccgcctgtttc
gcggcggcgctggacgcgctgccccggctcggtgccggcgccgaggtgacggacgccgtt
gcggggtacctggagcgctatgtcgcccggggccgctgtccggccgacgatctgctggac
gcgctgcccggcatccgtaccggcccggccgggagcggccccgccgcccagggcaggaag
gacatcccctcatga
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