Streptomyces sp. WP-1: QHG49_05035
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Entry
QHG49_05035 CDS
T10379
Name
(GenBank) NADP-dependent isocitrate dehydrogenase
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
strw Streptomyces sp. WP-1
Pathway
strw00020
Citrate cycle (TCA cycle)
strw00480
Glutathione metabolism
strw00720
Other carbon fixation pathways
strw01100
Metabolic pathways
strw01110
Biosynthesis of secondary metabolites
strw01120
Microbial metabolism in diverse environments
strw01200
Carbon metabolism
strw01210
2-Oxocarboxylic acid metabolism
strw01230
Biosynthesis of amino acids
strw04146
Peroxisome
Module
strw_M00009
Citrate cycle (TCA cycle, Krebs cycle)
strw_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
Enzymes [BR:
strw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
QHG49_05035
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NCBI-ProteinID:
WKE68435
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Position
1213755..1215974
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AA seq
739 aa
AA seq
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MTDSTIIYTYTDEAPALATHSFLPVVRAYASQAGVPVQTRDISLAGRIIAVFPEYLNEDQ
RIADALTELGELAKTPSANIIKLPNISASIPQLKAAIAELQGKGYALPDYPDDPKSDEER
EIRARYDKIKGSAVNPVLREGNSDRRAPASVKNYAKTHPHRMGAWTAESRTNVATMSDND
FASTEKSTVIAEDTTLRFELVGADGTTTELRAPLKVIAGEVVDAAVLRAAALNEFLAAQV
ARAKQEGVLFSVHLKATMMKVSDPIIFGHVVRTFFPKTFAKYGETLKAAGLSPNDGLGGI
YKGLENLPEGAEIKASFDAELADGPALAMVDSDKGITNLHVPSDVIVDASMPAMIRTSGH
MWGADGQEHDTLAVLPDHSYSGVYQAVIEDCRANGAFDPSTMGSVPNVGLMAQKAEEYGS
HDKTFEIPADGTVRLVDAAGNVVLEQAVAQGDIFRACQTKDDPIRDWVKLAVTRARATGD
PAVFWLDENRAHDAQLIAKVKEYLPEHDTEGLDIRILSPIEATKLSVERIRRGENTISVT
GNVLRDYLTDLFPILELGTSAKMLSVVPLMAGGGLFETGAGGSAPKHVQQLVKENYLRWD
SLGEFFALVPSLEQYAAATGNTRAKVLADALDRATATFLNEDKSPTRRLGGIDNRGSHFY
LSLYWAQELAKQTDDADLAKAFAPLAESLAADEQQIVSELNSVQGRPVDLGGYYRVDQEK
ADAVMRPSATWNAALASLS
NT seq
2220 nt
NT seq
+upstream
nt +downstream
nt
gtgactgactcgaccatcatctacacgtatacagacgaggccccggccctggcgacgcat
tcgttcctgccggtggtccgggcgtacgcctcgcaggccggtgtgcccgtgcagacccgc
gacatctcgctggccgggcgcatcatcgccgtattcccggagtacctgaacgaggaccag
cgcatcgcggacgcgctgaccgagctgggcgagcttgccaagaccccctcggccaacatc
atcaagctgccgaacatctcggcgtccatcccgcagctcaaggccgccatcgccgagctg
cagggcaagggctacgcgctgccggactacccggacgacccgaagtcggacgaggagcgc
gagatccgcgcccgctacgacaagatcaagggctccgcggtcaacccggtcctgcgtgag
ggcaactccgaccgccgcgccccggcctcggtgaagaactacgccaagacccacccgcac
cgcatgggcgcctggaccgccgagtccaggaccaatgtggcgaccatgagcgacaacgac
ttcgccagcacggagaagtccaccgtgatcgccgaggacaccaccctgcgcttcgagctg
gtcggcgccgacggcaccaccaccgagctgcgcgcgccgctcaaggtcatcgcgggtgag
gtcgtggacgccgccgtgctgcgcgccgccgccctcaacgagttcctcgccgcgcaggtc
gcccgcgccaagcaggagggcgtgctgttctccgtgcacctgaaggccacgatgatgaag
gtctccgacccgatcatcttcggtcacgtggtgcgcaccttcttcccgaagacgttcgcg
aagtacggcgagactctcaaggcggccggtctctccccgaacgacggcctcggcggcatc
tacaagggcctggagaacctgcccgagggtgccgagatcaaggcgtccttcgacgccgag
ctggccgacggcccggcgctggccatggtcgactccgacaagggcatcaccaacctgcac
gtcccctcggacgtcatcgtggacgcctccatgcccgcgatgatccgtacctccggccac
atgtggggcgcggacggccaggagcacgacaccctcgcggtgctgccggaccacagctac
tccggcgtctaccaggccgtgatcgaggactgccgcgccaacggcgccttcgacccgtcc
accatgggctcggtgccgaacgtcggcctcatggcgcagaaggccgaggagtacggctcc
cacgacaagaccttcgagatcccggccgacggcacggtccgcctggtcgacgcggccggc
aacgtggtcctggagcaggccgtggcccagggcgacatcttccgcgcctgccagaccaag
gacgacccgatccgcgactgggtcaagctggccgtcacccgcgcccgcgccaccggcgac
ccggccgtgttctggctggacgagaaccgcgcccacgacgcgcagctgatcgccaaggtc
aaggagtacctgccggagcacgacaccgagggcctggacatccggatcctgtccccgatc
gaggccaccaagctgtcggtggagcgcatccgccgcggcgagaacaccatctcggtcacc
ggcaacgtgctgcgcgactacctgaccgacctgttcccgatcctggagctgggcaccagc
gccaagatgctgtcggtcgtcccgctgatggcgggcggcggcctgttcgagaccggtgcc
ggcggctccgcgcccaagcacgtccagcagctggtcaaggagaactacctgcgctgggac
tcgctcggcgagttcttcgcgctcgtcccctccctggagcagtacgcggcggccaccggc
aacacccgcgccaaggtcctggccgacgccctggaccgcgccacggcgaccttcctcaac
gaggacaagtccccgacccgtcgcctcggcggcatcgacaaccgcggcagccacttctac
ctgtccctgtactgggcgcaggagctggccaagcagaccgacgacgccgacctggccaag
gcgttcgcgccgctcgccgagtccctcgcggccgacgagcagcagatcgtgtccgagctg
aacagcgtccagggccggccggtcgacctcggcggctactaccgcgtcgaccaggagaag
gcggacgcggtgatgcgtccgtcggccacctggaacgcggcgctcgcctcgctgagctga
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