Streptomyces sp. WP-1: QHG49_10850
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Entry
QHG49_10850 CDS
T10379
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
strw Streptomyces sp. WP-1
Pathway
strw00290
Valine, leucine and isoleucine biosynthesis
strw00660
C5-Branched dibasic acid metabolism
strw01100
Metabolic pathways
strw01110
Biosynthesis of secondary metabolites
strw01210
2-Oxocarboxylic acid metabolism
strw01230
Biosynthesis of amino acids
Module
strw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
strw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
QHG49_10850 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
QHG49_10850 (leuC)
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Motif
Pfam:
Aconitase
YopE_N
Motif
Other DBs
NCBI-ProteinID:
WKE69503
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Position
complement(2576850..2578274)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAQGEPDLLYIDLHLLHEVTSPQAFDGLRQNGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMVRPRTMAITVDGELPEGVSA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
EYLKGRPHAPEGAEWDAAVAYWRTLRTDDDAEFDAEVVIDAAALSPFVTWGTNPGQGAPL
SAQVPDPASYEDASERLAAEKALEYMGLEAGAPLRSIKVDTVFVGSCTNGRIEDLRNVAA
ILKDRKVADGVRMLVVPGSARVGLQAAAEGLDVVFKDAGAEWRYAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLAAPADLTDDRTPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggaaaaggtctgggacgaccacgtcgtccggcgcgcccagggc
gagcccgacctcctctacatcgatctgcacctgctccacgaggtgaccagcccgcaggcc
ttcgacgggctgcgccagaacggccgccaggtgcgccgcctcgacctcaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagccgatcgccgacccggtctcgcgc
gcccagctggagacgctgcgcaagaactgcgccgagttcggggtgcggctgcacccgctg
ggcgacgtcgaacagggcgtcgtgcacgtggtcggcccccagctgggcctgacccagccc
ggtacgaccgtggtgtgcggcgactcccacacctccacgcacggcgcgttcggcgcgctg
gcgttcggcatcggcacctcccaggtcgagcatgtgctggccacccagacgctgccgatg
gtccgccccaggaccatggcgatcaccgtggacggcgaactgcccgagggcgtcagcgcc
aaggacctgatcctggcgatcatcgcgcggatcggcaccggcggcggccagggctatgtc
ctggagtaccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gagtacctcaagggccgcccgcacgcccccgagggcgccgagtgggacgcggccgtcgcg
tactggaggacgctgcgcacggacgacgacgcggaattcgacgccgaggtcgtcatcgac
gccgccgcgctgtccccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcacaggtccccgatccggcttcgtacgaagacgcatcggagcgcctggccgccgaa
aaggccctggaatacatggggttggaggccggagcgccgctgcgctccatcaaggtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcaatgtcgccgcg
atcctgaaggaccgcaaagtcgccgacggtgtacggatgctggtcgtgccgggctccgcg
cgggtcggtctccaggcggccgccgagggcctggacgtggtcttcaaggacgccggcgcc
gagtggcggtacgcgggctgctcgatgtgcctgggcatgaacccggaccagctggccccg
ggcgagcgctccgcctccacctccaaccgcaacttcgagggccggcagggcaagggcggt
cgtacccacctggtgtcgccgcaggtcgcggcggccaccgccgtcctgggccacctggcc
gccccggccgacctgaccgacgaccgtacgcccgctggagtctga
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