Streptomyces sp. WP-1: QHG49_14125
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Entry
QHG49_14125 CDS
T10379
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
strw Streptomyces sp. WP-1
Pathway
strw00230
Purine metabolism
strw00670
One carbon pool by folate
strw01100
Metabolic pathways
strw01110
Biosynthesis of secondary metabolites
Module
strw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
strw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
QHG49_14125 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
QHG49_14125 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
strw04147
]
QHG49_14125 (purH)
Enzymes [BR:
strw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
QHG49_14125 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
QHG49_14125 (purH)
Exosome [BR:
strw04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
QHG49_14125 (purH)
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Gene cluster
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Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
WKE70099
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Position
complement(3299383..3300945)
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AA seq
520 aa
AA seq
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MTAESNKRPLRRALVSVYDKTGLEELARGLHEAGVELVSTGSTASRIAAAGVPVTKVEEL
TGFPECLDGRVKTLHPKVHAGILADLRLDSHRAQLDELGVAPFDLVVVNLYPFRETVASG
ASADECVEQIDIGGPSMVRAAAKNHPSVAVVTSPARYADVLAAVKDGGFDLAARKRLAAE
AFKHTAAYDVAVASWFAADYAPVDDSAFPDFTGATYERKNTLRYGENPHQGAALYVDGTG
GLAEAEQLQGKEMSYNNYTDTDAARRAAYDHAEPCVAIIKHANPCGIAVGADVAEAHRKA
HACDPLSAFGGVIAVNRPVSKEMAEQVAEIFTEVIVAPDYEEGALEALTKKKNIRVLKAE
GGPANAVEAKPVDGGLLLQAADRLQAEGDDPAHWTLATGEALSAEELKDLAFAWKACRAV
KSNAILLAKDGASVGVGMGQVNRVDSCKLAVERAGEERARGSYAASDAFFPFPDGPQILI
DAGVRAIVQPGGSVRDELAVEAAQKAGVTMYFTGTRHFFH
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgccgagagcaacaagcggccccttcgcagggcgctcgtcagcgtctacgacaag
accggcctggaagagctggcgcgcgggctgcacgaggccggggtcgagctggtgtcgacc
ggttccaccgcctcccgcatcgccgccgccggcgtcccggtcacgaaggtcgaggagctg
accggcttccccgagtgcctggacggccgggtcaagaccctgcacccgaaggtgcacgcg
ggcatcctcgccgacctgcgcctggacagccaccgcgcgcagctcgacgagctgggcgtg
gcgccgttcgacctggtcgtcgtgaacctctacccgttccgcgagaccgtcgcctccggt
gcctcggccgacgagtgcgtggagcagatcgacatcggcggcccctcgatggtccgcgcc
gccgccaagaaccacccctcggtcgccgtggtcaccagccccgcccggtacgcggacgtc
ctcgcggccgtcaaggacggcggcttcgacctggccgcccgcaagcggctggccgccgag
gcgttcaagcacaccgccgcctacgacgtggccgtcgcctcctggttcgccgccgactac
gcccccgtggacgactcggccttcccggacttcaccggcgccacctacgagcgcaagaac
accctgcgctacggcgagaacccgcaccagggcgccgcgctgtacgtcgacggcacgggc
ggcctggccgaggcggagcagctgcaaggcaaggagatgtcgtacaacaactacacggac
acggacgccgcgcgccgtgccgcgtacgaccacgccgagccctgcgtcgcgatcatcaag
cacgcgaacccctgcggcatcgcggtcggcgcggacgtcgccgaggcgcaccgcaaggcg
cacgcctgcgacccgctgtccgcgttcggcggcgtcatcgccgtgaaccggccggtcagc
aaggagatggccgagcaggtcgcggagatcttcaccgaggtcatcgtcgccccggactac
gaggagggggccctggaggccctcaccaagaagaagaacatccgggtgctgaaggccgag
ggcggccccgccaacgcggtcgaggccaagccggtcgacggcggtctgctgctccaggcc
gccgaccggctccaggccgagggcgacgaccccgcgcactggacgctggccaccggtgag
gcgctgtccgccgaggagctgaaggacctcgcgttcgcctggaaggcgtgccgcgcggtg
aagtccaacgcgatcctgctcgccaaggacggcgcctcggtcggcgtcggcatgggccag
gtcaaccgcgtcgactcctgcaagctcgcggtcgagcgggccggcgaggagcgcgcccgg
ggttcctacgcggcctccgacgccttcttcccgttccccgacggcccgcagatcctgatc
gacgcgggtgtccgcgcgatcgtccagcccggcggttccgtccgggacgagctggccgtc
gaggcggcccagaaggcgggcgtgaccatgtacttcacgggcacgcgccacttcttccac
tga
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