Streptomyces sp. WP-1: QHG49_18440
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Entry
QHG49_18440 CDS
T10379
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit PurL
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
strw Streptomyces sp. WP-1
Pathway
strw00230
Purine metabolism
strw01100
Metabolic pathways
strw01110
Biosynthesis of secondary metabolites
Module
strw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
strw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
QHG49_18440 (purL)
Enzymes [BR:
strw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
QHG49_18440 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
WKE70868
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Position
4231765..4234023
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AA seq
752 aa
AA seq
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MSRTPLDTVEHAAATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCS
YKSSKVHLRQFGEKAPESDALLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAA
TGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGE
VVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNQVILYGARTGGDGIGGASILASET
FDDAKPSKRPAVQVGDPFQEKLLIECTLEAFREKLVVGIQDLGAAGLSCATSELASNGSG
GMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPSKVERFLEICEKWDVIATVIGEVT
DGDRLEIFWHGGKIVDVDPRTVAHDGPVYERPYARPSWQDALQADDANKLPRPATAEELK
DQVLKLVGSPNQASKKWITQQYDHFVQGNTVLAQPEDSGMIRVDEESGLGVAIATDGNGR
YAKLDPYTGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAVRGLADGC
QQLGTPVTGGNVSLYNQTGEAAIHPTPVVAVLGVIDDVARRTPVAFQEEGQLLYLLGDTR
EEFGGSAWSQVIHDHLGGMPPVVDLERERLLAEILISASRDGMIDSAHDLSDGGLAQAVV
ESALLGGKGARLVVPDGLDAFTFLLSESAGRALVAVPRSEELRFTDMCGARGLPATRIGV
VDGDALDVQGEFTLPLSDLREAHESTIPALLA
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atgagccgcacgcctctggacacggtcgagcacgcggccgcgactcccgacgtcgagctg
ccctgggccgaactcggtctgaagaaggacgagtacgagcgggtggtggagatcctcggc
cgccgcccgaccggcgcggagctcgccatgtactcggtcatgtggtccgagcactgctcg
tacaagtcctccaaggtccatctgcgccagttcggcgagaaggcgcccgagtcggacgcg
ctgctcgtcggcatcggcgagaacgccggtgtggtggacgtcggccagggttacgcggtc
accttcaaggtcgagtcgcacaaccacccctcgtacgtggagccctaccagggcgcggcc
acgggcgtcggcggcatcgtccgcgacatcatcgcgatgggcgcccgcccggtcgcggtg
gtcgacccgctgcgcttcggcgcggccgaccaccccgacaccaagcgcgtcctgccgggc
gtggtcgcgggcatcggcggctacggcaactgcctgggcctgcccaacatcggcggcgag
gtcgtcttcgacgcctgctaccagggcaacccgctggtcaacgccggtgccatcggtgtg
atgcggcacgaggacatccacctcgccaaggcctccggcgcgggcaaccaggtcatcctg
tacggcgcccggaccggcggcgacggcatcggcggcgcctcgatcctcgcgtccgagacc
ttcgacgacgccaagccctcgaagcggcccgcggtgcaggtcggcgaccccttccaggag
aagctcctcatcgagtgcaccctggaggcgttccgggagaagctggtcgtcggcatccag
gacctgggcgcggccggactctcctgcgcgaccagcgagctggcgtccaacggctccggc
ggcatgcgcgtcaccctggacgacgtcccgctgcgcgactcgacgctctcgcccgaggag
atcctcatgagcgagtcgcaggaacgcatgtgcgcggtcgtggagccctcgaaggtcgag
cggttcctggagatctgcgagaagtgggacgtcatcgccaccgtcatcggtgaggtgacc
gacggcgaccggctggagatcttctggcacggcggcaagatcgtggacgtcgacccgcgc
acggtcgcgcacgacggcccggtctacgagcgcccgtacgcgcgcccctcctggcaggac
gcgctccaggccgacgacgcgaacaagctgccgcgcccggcgaccgccgaggagctgaag
gaccaggtcctcaagctcgtcgggtccccgaaccaggcgtccaagaagtggatcacccag
cagtacgaccacttcgtgcagggcaacacggtgctggcgcagcccgaggactccggcatg
atccgcgtggacgaggagtccgggctcggcgtcgccatcgcgacggacggcaacggccgc
tacgccaagctggacccgtacacgggcgcgcagctggcgctggcggaggcgtaccggaac
gtggcgacgacgggtgcgaagccgctcgcggtctcggactgcctgaacttcggctcgccc
gaggacccggcggtgatgtggcagttcgcggaggcggtacgtggtctcgcggacggctgc
cagcagctcggcaccccggtgaccggcggcaatgtctcgctctacaaccagacgggcgag
gcggcgatccacccgacgccggtcgtcgcggtcctcggtgtgatcgacgacgtcgcccgc
cgcaccccggtcgccttccaggaggaggggcagctgctctatctcctcggcgacacccgc
gaggagttcggcggctcggcctggtcccaggtgatccacgaccacctgggcggcatgcct
ccggtggtcgacctggagcgggagcggctgctggccgagatcctgatctccgcctcccgc
gacggcatgatcgactccgcgcacgacctgtccgacggcggtctcgcgcaggccgtggtc
gagtcggcgctgctgggcgggaagggcgcgcgcctggtcgtccccgacggcctggacgcc
ttcaccttcctcctctccgagtcggctggccgcgccctcgtggccgtcccccgctcggag
gagctccgcttcaccgacatgtgcggcgcgcgcggcctgccggccacccgcatcggtgtc
gtggacggcgacgcgctggacgtccagggcgagttcaccctccccctgtccgacctgcgc
gaggcccacgagagcacgatccccgcgctgctggcgtga
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