Streptomyces sp. S6: EQG64_07210
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Entry
EQG64_07210 CDS
T07981
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stry
Streptomyces sp. S6
Pathway
stry00300
Lysine biosynthesis
stry00550
Peptidoglycan biosynthesis
stry01100
Metabolic pathways
stry01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stry00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EQG64_07210 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EQG64_07210 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EQG64_07210 (murF)
Enzymes [BR:
stry01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EQG64_07210 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
APH
DUF561
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
QCW77348
LinkDB
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Position
complement(1658041..1659462)
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AA seq
473 aa
AA seq
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MITLSLAEIAEIVGGQPHDIPDPAVTVTGPVVIDSREVAPGSLFAAFAGERVDGHDYAQR
AVEAGAAAVLAARPVGVPAIVVDDVVGALGALARTVVERLGTTVVALTGSAGKTSTKDLI
AQLLQRKAPTVWTPGSLNNEIGLPLTALSATSETQHLVLEMGARGIGHIHYLAQLTPPRI
GLVLNVGSAHLGEFGSREAIARAKGELVEALPGDGCAVLNADDPLVRAMASRTEARVLLF
GEAPEADVRGENVRMTPDGRAAFQLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHELGMS
VTEIAEALSEAGTLSRWRMEVTERGDGVTVVNDAYNANPESMRAALRALAAMGQARAADG
GRTWAVLGQMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEKVAQALLENATEGEVAGR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaccctttccctcgccgagatcgccgaaatcgtcggcgggcagccgcacgacata
ccggacccggcagtcaccgtcaccggccccgtcgtcatcgactcccgcgaggtcgcgccc
ggcagcctgttcgccgcgttcgccggcgaacgggtggacggccacgactacgcgcagcgc
gccgtcgaggcgggcgcggcagccgtcctggccgcccgccccgtcggcgttccggcgatc
gtcgtggacgacgtcgtcggcgcgctcggcgccctcgcccgtaccgtcgtcgaacgcctc
ggcaccaccgtcgtcgcgctcaccggctccgcgggcaagacctccaccaaggacctcatc
gcgcagctcctgcagcgcaaggcccccacggtctggacgccgggctccctcaacaacgag
atcggcctgccgctcaccgccctgagcgccacctcagagacccagcacctggtcctggag
atgggcgcccgcggcatcgggcacatccactacctggcccagctgaccccgccccgcatc
ggtctggtcctcaacgtcggctccgcccacctcggggagttcggcagccgcgaggcgatc
gcccgggccaagggcgagctggtcgaggcgctccccggggacggctgcgccgtgctcaac
gccgacgacccgctcgtacgcgcgatggcttcgcgcaccgaggcccgcgtcctgctcttc
ggagaagccccggaagcggacgtacggggcgagaacgtccggatgacccccgacgggcgg
gccgctttccagctccacacacccaccgggtgcagcgacgtgaccttgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttgggcatgtcc
gtgaccgagatcgccgaggcgctctcggaggcgggcaccctctcccgctggcgcatggag
gtcaccgagcgcggggacggtgtgacggtcgtcaacgacgcctacaacgcgaaccccgaa
tccatgagagccgcactgcgtgcgctggctgccatgggccaggcccgagcggccgacggg
gggcgcacctgggcggtgctcggtcagatggccgagctgggtgacgcgtcgctcgccgag
cacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgctgtcggg
ggcagagaagcctcctggctgcaactgggcgcatataacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcgcaggcggccgtcgacctgttgcgcagtgaactgcgcccg
ggagacgtcgtgctggtgaaggcgtcccggtcggtcggcctggagaaggtcgcccaggca
ctgctggagaacgcgaccgagggcgaggtcgccggccgatga
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