Streptomyces sp. 71268: OYE22_07930
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Entry
OYE22_07930 CDS
T09829
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
strz
Streptomyces sp. 71268
Pathway
strz00290
Valine, leucine and isoleucine biosynthesis
strz00660
C5-Branched dibasic acid metabolism
strz01100
Metabolic pathways
strz01110
Biosynthesis of secondary metabolites
strz01210
2-Oxocarboxylic acid metabolism
strz01230
Biosynthesis of amino acids
Module
strz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
strz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
OYE22_07930 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OYE22_07930 (leuC)
Enzymes [BR:
strz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
OYE22_07930 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
OYE22_07930 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
WEV25130
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Position
complement(2167876..2169300)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRRVRRTDLTIAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLAPFRTMAITVEGELPADVTA
KDLILAVIAKIGTGGGQGYVIEYRGEAIEKLSMEARMTVCNMSIEAGARAGMIAPDETTF
AYLKGRDHAPRGEQWDEAVAYWRTLRTDEDATFDREVVIDAATLAPFVTWGTNPGQGAPL
SASVPDPASYADASERQAAEKALEYMGLTAGQALRDISVDTVFVGSCTNGRIEDLRAAAA
VLEGRQVAEGVRMLVVPGSVRVALQAVQEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVRGSLASPADLAPSTAPVGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggacggacactggcggagaaggtctgggacgatcacgtcgtccggcgcgccgagggc
gagcccgacttgctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcg
ttcgacgggctccgcaaggcggggcggcgggtgcggcgtaccgacctcaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgcggaccccgtatcccgc
acccaactggagacgctgcgcaagaactgcgcggagttcggcgtccgcctgcacccgctg
ggcgacgtcgagcagggcgtggtgcacgtcgtggggccgcagttggggctgacccagccg
ggcaccacggtggtgtgcggggacagccacacctccacgcacggggcgttcggcgccctc
gcgttcgggatcggcacctcgcaggtggagcacgtgctggccacccagacgctgccgctg
gccccgttcaggacgatggccatcaccgtcgagggcgaactgcccgcggacgtcaccgcg
aaggacctgatcctcgcggtcatcgcgaagatcggcaccggtggcggccaggggtacgtc
atcgagtaccgcggcgaggccatcgagaagctgtcgatggaagcgcggatgaccgtgtgc
aacatgtccatcgaggccggcgcgcgggccgggatgatcgcccccgacgagaccaccttc
gcctatctcaagggtcgcgaccacgcgccccgtggcgagcagtgggacgaggcggtggcc
tactggcgcaccctgcgcaccgacgaggacgccaccttcgaccgcgaggtggtcatcgac
gcggcgacgctggccccgttcgtcacctggggcaccaatccggggcagggtgccccgttg
tcggcgtccgtgcccgaccccgcctcgtacgcggacgccagcgagcgccaggcggccgaa
aaggccctggagtacatggggttgacggccggtcaggcgctgcgcgacatcagcgtggac
accgtgttcgtcgggtcgtgcaccaacggccggatcgaggacctgcgcgcggccgccgcc
gtgctggaggggcgccaggttgccgagggcgtccggatgctggtggttccgggttcggta
cgggtggccctgcaggcggtgcaggagggactggacaaggtcttcaccgcggccggggcc
gaatggcggcacgccgggtgctcgatgtgcctgggcatgaaccccgaccagctcgctccc
ggcgagcgttccgcctccacctccaaccgcaacttcgagggacgtcaggggaagggcggg
cgtacgcacctggtctcgccccaggtcgccgccgccacggccgtgcgcggcagcctcgcc
tcgcccgccgacctcgctccgtcaaccgctcccgtgggggtctga
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