Streptomyces sp. 71268: OYE22_20465
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Entry
OYE22_20465 CDS
T09829
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
strz
Streptomyces sp. 71268
Pathway
strz00230
Purine metabolism
strz00670
One carbon pool by folate
strz01100
Metabolic pathways
strz01110
Biosynthesis of secondary metabolites
Module
strz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
strz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
OYE22_20465 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
OYE22_20465 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
strz04147
]
OYE22_20465 (purH)
Enzymes [BR:
strz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
OYE22_20465 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
OYE22_20465 (purH)
Exosome [BR:
strz04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
OYE22_20465 (purH)
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Gene cluster
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Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
WEV27305
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Position
5179763..5181328
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AA seq
521 aa
AA seq
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MTVEGTKRPIRRALVSVYDKSGLEELALGLHAAGVQLVSTGSTAGKIAAAGVPVTRVEEL
TGFPECLDGRVKTLHPRVHAGILADQRLEAHREQLAELGVEPFELVIVNLYPFEETVASG
ADPDACVEQIDIGGPSMVRAAAKNHPSVAVVVNPDRYPQVLTAVADGGFDLDHRKRLAAE
AFHHTAAYDTAVASWFAADYVGDGEEFPGFVGATYERKNVLRYGENPHQAAALYTAGDGG
LAEAEQLHGKEMSYNNYVDTDAARRAAYDHGADQACVAIIKHANPCGIAVGADVAEAHRK
AHACDPLSAFGGVIAVNQPVSRAMAEQVADIFTEVIIAPDYEEGAVEALAKKKNIRVLRC
PQAPAARVEFRPIDGGGLAQAKDAFQAEGDDPANWTLATGEALDAAGLAELAFAWRACRA
VKSNAILLAKDGATVGVGMGQVNRVDSARLAVQRAGEERARGAYAASDAFFPFPDGLEVL
TEAGVRAVVQPGGSVRDEQVVEAAKAAGVTMYFTGTRHFFH
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtcgaaggtacgaagcggcccatccgccgcgcgctggtcagcgtctacgacaag
agtgggctcgaggagctggcgctcggcctgcacgccgcgggcgtccagctcgtctcgacc
ggctcgacggccgggaagatcgccgcggccggggtgccggtgaccagggtcgaggagctg
accgggttcccggagtgcctggacggccgggtcaagaccctgcacccgcgcgtgcacgcg
ggcatcctcgccgaccagcgtcttgaggcgcaccgcgagcagctcgccgagctgggcgtg
gagccgttcgagctggtgatcgtgaacctgtacccgttcgaggagaccgtggcctcgggc
gcggacccggacgcgtgcgtggagcagatcgacatcggcgggccctccatggtccgcgcc
gccgccaagaaccatccgtcggtggccgtggtcgtcaaccccgaccgctacccgcaggtg
ctcaccgccgtggccgacggtggtttcgacctcgaccaccgcaagcggctggccgccgag
gcgttccaccacaccgccgcgtacgacacggccgtcgcctcctggttcgccgccgactac
gtcggggacggcgaggagttccccggcttcgtcggcgccacctacgagcgcaagaacgtg
ctgcgctacggcgagaacccgcaccaggccgcggccctctacaccgcgggcgacgggggc
ctggccgaggccgagcagctgcacggcaaggagatgtcgtacaacaactacgtcgacacc
gacgccgcgcgccgcgccgcctacgaccacggcgccgaccaggcgtgcgtggccatcatc
aagcacgccaacccgtgtggcatcgcggtcggcgcggacgtcgccgaggcgcaccgcaag
gcgcacgcctgcgacccgctgtccgccttcggcggcgtgatcgcggtcaaccagccggtc
tcgcgcgccatggccgagcaggtcgccgacatcttcaccgaggtcatcatcgccccggac
tacgaggagggcgccgtcgaggcgctcgccaagaagaagaacatccgggtgctgcgctgc
ccgcaggcccccgccgcgcgggtggagttccgcccgatcgacggcggtggcctggcccag
gccaaggacgccttccaggccgagggcgacgacccggcgaactggaccctggccaccggc
gaggcgctggacgcggccgggctcgccgagctggcgttcgcctggcgcgcctgccgcgcg
gtcaagtccaacgcgatcctgctggccaaggacggcgccacggtcggcgtcggcatgggc
caggtcaaccgggtggactcggcgcgcctcgcggtgcagcgcgcgggcgaggagcgggcg
cggggcgcgtacgccgcctccgacgcgttcttccccttccctgacggcctcgaggtgctg
accgaggccggcgtcagggccgtggtgcagcccggcggttcggtccgcgacgagcaggtc
gtcgaggccgcgaaggcggccggcgtgaccatgtacttcacgggcacgcgccacttcttc
cactga
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