Streptomyces sp. 71268: OYE22_23745
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Entry
OYE22_23745 CDS
T09829
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
strz
Streptomyces sp. 71268
Pathway
strz00790
Folate biosynthesis
strz01100
Metabolic pathways
strz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
strz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
OYE22_23745
Enzymes [BR:
strz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
OYE22_23745
6.3.2.17 tetrahydrofolate synthase
OYE22_23745
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
WEV27855
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Position
5988191..5989735
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AA seq
514 aa
AA seq
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MSERPPSDESEPDGLDAFDEIIEAETERDPDLAVIEAGSRTLRAQAGPPQDDGVPSRPQD
PELDRALREVETELASRWGETKLDPSVQRIKAVLDILGEPQRAYPAIHITGTNGKTSTAR
MIEALLGAFELRTGRYTSPHVQSITERISLDGAPISAERFIETYRDIQPYVEMTDAQQEF
RLSFFEVLTAMAYAAFADAPVDVAVVEVGMGGTWDATNVIDAAVAVVTPISLDHTDRLGG
THEAIATEKAGIIKALDGADGAAGATVVLAQQPVEAASVLLKRAVEVDATVAREGMEFGV
LSREVAVGGQLLTLRGLGGEYPDLFLPLHGAHMAHNAAVALAAVEAFFGIGSQHARTLDL
DTVRAALAGVSSPGRLEVVRRSPTVVLDAAHNPGGARAAAEAVSEAFAFSRLIGVVACST
GKDVRGLLEAFEPLFTEIVVTRYAHDRALDVDELAAVAVEVFGPDRVQVEPRLDEAIDVA
VTLAEEEGEFSSAGVLITGSVITVGEARLLLGRE
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagcgccccccgagtgacgaatccgagcccgacgggctcgacgccttcgacgag
atcattgaggccgagaccgagcgcgaccccgaccttgccgtgatcgaggcgggaagtcgc
accctgcgcgcccaggccggcccgccccaggacgacggcgtgccgtcccgtccccaggac
cccgagctggaccgcgcgctgcgcgaggtcgagacggagctggccagccgctggggggag
accaagctcgacccgtcggtgcagcgcatcaaggcggtcctggacatcctcggcgagccg
cagcgcgcgtacccggcgatccacatcaccggcaccaacggcaagaccagcacggcccgg
atgatcgaggccctgctcggcgccttcgagctgcgcaccgggcggtacaccagcccccac
gtgcagtcgatcaccgagcggatcagcctggacggcgccccgatctcagccgagcggttc
atcgagacctaccgcgacatccagccgtacgtggagatgaccgacgcccagcaggagttc
cggctctccttcttcgaggtgctgacggcgatggcgtacgcggcgttcgccgacgcgccg
gtggacgtcgcggtggtcgaggtcggcatgggcggcacctgggacgcgaccaacgtcatc
gacgcggcggtcgccgtggtcaccccgatctcgctggaccatacggaccggctgggcggc
acgcacgaggcgatcgccaccgagaaggcggggatcatcaaggccctggacggggccgac
ggcgccgccggagccacggtggtcctcgcccaacagccggtggaggccgcgtcggtgctg
ctcaagcgggccgtcgaggtggatgccacggtggccagggagggcatggagttcggcgtg
ctgagccgggaggtcgcggtcgggggccagctcctgacgctgcgcggcctcggcggcgag
tacccggacctcttcctcccgctgcacggcgcgcacatggcgcacaacgcggccgtggcg
ctcgccgccgtcgaggcgttcttcggcatcggctcgcagcacgccaggacgctcgacctg
gacacggtccgggcggcgctcgcgggcgtcagctcgccgggccggctcgaggtggtgcgc
cgcagcccgaccgtggtgctggacgcggcgcacaacccggggggcgcgcgggccgcggcc
gaggcggtcagcgaggcgttcgccttcagccggctgatcggcgtggtcgcgtgcagcacg
ggcaaggacgtgcgcggcctgctggaggcgttcgagccgctgttcaccgagatcgtggtg
acgcggtacgcgcacgaccgggcgctggacgtggacgagctggcggccgtcgccgtcgag
gtcttcgggcccgaccgggtgcaggtcgagccgaggctggacgaggcgatcgacgtcgcc
gtcacgctcgccgaggaggagggcgagttctccagcgccggcgtgctgatcaccggctcc
gtcatcaccgtgggcgaggcccggctgctcctgggaagggagtaa
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