Streptomyces sp. 71268: OYE22_26370
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Entry
OYE22_26370 CDS
T09829
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
strz
Streptomyces sp. 71268
Pathway
strz00300
Lysine biosynthesis
strz00550
Peptidoglycan biosynthesis
strz01100
Metabolic pathways
strz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
OYE22_26370
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
OYE22_26370
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
OYE22_26370
Enzymes [BR:
strz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
OYE22_26370
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
GntR
DUF2126
Motif
Other DBs
NCBI-ProteinID:
WEV28310
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Position
6610580..6612016
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AA seq
478 aa
AA seq
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MISLSLAEVTAIVGGQPYDIPDLDQRVSGPVVIDSREVRPGGLFAAFAGERVDGHDYAER
AVAAGAVAVVATRPVGVPAIVVDDVVAALGALARAVVERLGARVVGLTGSAGKTSTKDLI
AQLLERLGPTVWTPGSFNNEIGMPLTALRADDETRHLVLEMGARGIGHIRYLAELTPPHI
GLVLNVGTAHIGEFGGREQIAQAKGELVEGLPTAEAGGVAVLNADDPLVRAMSARTQAEV
LLFGEAAEAHVRAENVRLTDLGQPSFTLHTPTGCGDVTMRLYGEHHVSNALAAAAVAHVL
GMSAPEIAEALSEAGQLSRWRMEVTERADGVTIVNDAYNANPESMRAALRALVAMGTAHR
AQGGRTWAVLGQMAELGEESLVEHDAIGRLAVRLNVSKLVAVGGQEAAWIDMGAKNEGSW
GEESVHVSDARAAVELLRRELRPGDIALVKASRSVGLEQVAAELLGEPGTAEGEGAGR
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
gtgatctcgctgtccctcgccgaggtcaccgccatcgtcggcgggcagccgtacgacata
ccggacctcgaccagcgggtctccgggcccgtggtgatcgactcccgtgaggtgcgcccc
ggcggcctgttcgccgcgttcgccggcgagcgggtcgacgggcacgactacgccgaacgc
gccgtcgccgccggcgcggtggcggtggtggccacgcgccccgtcggcgtgcccgccatc
gtcgtggacgacgtggtggccgcgctcggcgcgctcgcccgcgccgtcgtcgagcggctc
ggcgcccgcgtcgtcggcctcaccggctcggccggcaagaccagcaccaaggacctgatc
gcccaactcctggagcggctcgggccgaccgtgtggacgccgggctcgttcaacaacgag
atcggcatgccgctgacggcgctgcgcgccgacgacgagacccgccacctcgtcctggag
atgggcgcccgcggcatcggccacatccgctacctggccgaactgacgcccccgcacatc
ggcctggtgctcaacgtcggcaccgcgcacatcggggagttcggcggccgcgagcagatc
gcccaggccaagggcgaactcgtggaggggctgccgacggccgaggcgggcggcgtggcc
gtgctcaacgccgacgacccgctggtgcgcgccatgagcgcgcgtacccaggcggaggtc
ctgttgttcggtgaggccgccgaggcccacgtacgcgccgagaatgtccggcttaccgac
ctcggacagcccagcttcacgcttcacacacccaccgggtgcggcgacgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgctgccgccgtcgcccatgtgttg
ggcatgtccgccccagagatcgccgaggcgctctccgaggcgggacagctctcccgctgg
cggatggaggtcaccgagcgcgcggacggcgtgacgatcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgcgctgcgcgcgctcgtggcgatgggcacggcccaccgg
gcgcaggggggacgcacgtgggcggtgctcggtcagatggccgaactcggcgaggagtca
ctcgtcgagcacgacgcgatcggacggctggccgttcgactcaacgtcagcaagctcgtg
gcggtcggcggccaggaggccgcctggatcgacatgggcgccaagaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcggtcgaactgttgcgcagagag
ttgcgcccgggagacatcgcgctggtgaaggcgtccaggtcggtcggcctggagcaggtc
gcggcggagctgttgggggaaccgggcacggccgagggcgagggtgccgggcgatga
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